Ligand Recognition by E-Selectin: Synthesis, Inhibitory Activity and Conformational Analysis of Bivalent Sialyl Lewis x Analogs

Shawn A. DeFrees; Winfried Kosch; William Way; James C. Paulson; Subramanian Sabesan; Randall L. Halcomb; Dee-Hua Huang; Yoshitaka Ichikawa; Chi-Huey Wong

doi:10.1021/ja00106a008

Ligand Recognition by E-Selectin: Synthesis, Inhibitory Activity and Conformational Analysis of Bivalent Sialyl Lewis x Analogs

Journal of the American Chemical Society ◽

10.1021/ja00106a008 ◽

1995 ◽

Vol 117 (1) ◽

pp. 66-79 ◽

Cited By ~ 85

Author(s):

Shawn A. DeFrees ◽

Winfried Kosch ◽

William Way ◽

James C. Paulson ◽

Subramanian Sabesan ◽

...

Keyword(s):

Conformational Analysis ◽

Inhibitory Activity ◽

Sialyl Lewis X ◽

Ligand Recognition ◽

Lewis X ◽

Sialyl Lewis

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Ligand Recognition by E- and P-Selectin: Chemoenzymatic Synthesis and Inhibitory Activity of Bivalent Sialyl Lewis x Derivatives and Sialyl Lewis x Carboxylic Acids

The Journal of Organic Chemistry ◽

10.1021/jo980350s ◽

1998 ◽

Vol 63 (15) ◽

pp. 5137-5143 ◽

Cited By ~ 30

Author(s):

Valentin Wittmann ◽

Shuichi Takayama ◽

Ke Wei Gong ◽

Gabriele Weitz-Schmidt ◽

Chi-Huey Wong

Keyword(s):

Carboxylic Acids ◽

Inhibitory Activity ◽

Chemoenzymatic Synthesis ◽

Sialyl Lewis X ◽

Ligand Recognition ◽

Lewis X ◽

Sialyl Lewis

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Chemical-enzymic synthesis and conformational analysis of sialyl Lewis X and derivatives

Journal of the American Chemical Society ◽

10.1021/ja00050a007 ◽

1992 ◽

Vol 114 (24) ◽

pp. 9283-9298 ◽

Cited By ~ 270

Author(s):

Yoshitaka Ichikawa ◽

Ying Chih Lin ◽

David P. Dumas ◽

Gwo Jenn Shen ◽

Eduardo Garcia-Junceda ◽

...

Keyword(s):

Conformational Analysis ◽

Sialyl Lewis X ◽

Lewis X ◽

Enzymic Synthesis ◽

Sialyl Lewis

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Synthetic Studies on Sialoglycoconjugates 81: Synthesis of Positional Isomers of Sialyl Lewis X Epitope Containing 1-Deoxy-dGlucose in Place ofN-Acetylglucosamine, and Their Inhibitory Activity to Selectin-Mediated Adhesion

Journal of Carbohydrate Chemistry ◽

10.1080/07328309608005435 ◽

1996 ◽

Vol 15 (2) ◽

pp. 147-162 ◽

Cited By ~ 2

Author(s):

Masahiro Yoshida ◽

Takako Suzuki ◽

Hideharu Ishida ◽

Makoto Kiso ◽

Akira Hasegawa

Keyword(s):

Inhibitory Activity ◽

Sialyl Lewis X ◽

Positional Isomers ◽

Lewis X ◽

Sialyl Lewis ◽

Synthetic Studies

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ChemInform Abstract: Chemical-Enzymatic Synthesis and Conformational Analysis of Sialyl Lewis x and Derivatives.

ChemInform ◽

10.1002/chin.199311273 ◽

2010 ◽

Vol 24 (11) ◽

pp. no-no

Author(s):

Y. ICHIKAWA ◽

Y.-C. LIN ◽

D. P. DUMAS ◽

G.-J. SHEN ◽

E. GARCIA-JUNCEDA ◽

...

Keyword(s):

Conformational Analysis ◽

Enzymatic Synthesis ◽

Sialyl Lewis X ◽

Lewis X ◽

Sialyl Lewis

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Ligand recognition by E-selectin: analysis of conformation and activity of synthetic monomeric and bivalent sialyl Lewis X analogs

Journal of the American Chemical Society ◽

10.1021/ja00069a083 ◽

1993 ◽

Vol 115 (16) ◽

pp. 7549-7550 ◽

Cited By ~ 59

Author(s):

Shawn A. DeFrees ◽

Federico C. A. Gaeta ◽

Ying Chih Lin ◽

Yoshitaka Ichikawa ◽

Chi Huey Wong

Keyword(s):

Sialyl Lewis X ◽

Ligand Recognition ◽

Lewis X ◽

Sialyl Lewis

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1005: Positive Correlation between the Expression Level of Sialyl Lewis X Antigen and Histopathological Findings in Patients with Renal Cell Carcinoma

The Journal of Urology ◽

10.1016/s0022-5347(18)38242-9 ◽

2004 ◽

Vol 171 (4S) ◽

pp. 266-266

Author(s):

Keiichi Tozawa ◽

Kenjiro Kohri ◽

Daisuke Nagata ◽

Katsuhiro Fukuta ◽

...

Keyword(s):

Renal Cell Carcinoma ◽

Cell Carcinoma ◽

Renal Cell ◽

Expression Level ◽

Sialyl Lewis X ◽

Lewis X ◽

Histopathological Findings ◽

Positive Correlation ◽

Sialyl Lewis ◽

Sialyl Lewis X Antigen

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Die Expression von Sialyl Lewis A, Sialyl Lewis X, Lewis Y und Thomsen-Friedenreich Antigen in zervikalen Dysplasien und invasiven Zervixkarzinomen

Geburtshilfe und Frauenheilkunde ◽

10.1055/s-0031-1278577 ◽

2011 ◽

Vol 71 (05) ◽

Author(s):

V Engelstaedter ◽

B Fluegel ◽

S Kunze ◽

F Bergauer ◽

D Mayr ◽

...

Keyword(s):

Sialyl Lewis X ◽

Lewis X ◽

Sialyl Lewis ◽

Sialyl Lewis A ◽

Lewis Y ◽

Lewis A

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Faculty Opinions recommendation of Human sperm binding is mediated by the sialyl-Lewis(x) oligosaccharide on the zona pellucida.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.13396969.14765074 ◽

2011 ◽

Author(s):

Dolores Lamb ◽

Alexander W Pastuszak

Keyword(s):

Zona Pellucida ◽

Human Sperm ◽

Sialyl Lewis X ◽

Lewis X ◽

Sperm Binding ◽

Sialyl Lewis

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Persistent HIV Transcription Induces Sialyl-Lewis-X Glyco-Antigen Cell-Surface Expression

SSRN Electronic Journal ◽

10.2139/ssrn.3565035 ◽

2020 ◽

Author(s):

Florent Colomb ◽

Leila B. Giron ◽

Leticia Kuri Cervantes ◽

Tongcui Ma ◽

Samson Adeniji ◽

...

Keyword(s):

Cell Surface ◽

Surface Expression ◽

Sialyl Lewis X ◽

Cell Surface Expression ◽

Lewis X ◽

Hiv Transcription ◽

Sialyl Lewis

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Sialyl Lewis X mimics derived from a pharmacophore search are selectin inhibitors with anti-inflammatory activity.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(17)32068-9 ◽

1994 ◽

Vol 269 (31) ◽

pp. 19663-19666

Author(s):

B.N. Rao ◽

M.B. Anderson ◽

J.H. Musser ◽

J.H. Gilbert ◽

M.E. Schaefer ◽

...

Keyword(s):

Inflammatory Activity ◽

Sialyl Lewis X ◽

Lewis X ◽

Sialyl Lewis ◽

Anti Inflammatory

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