Determination of G*G.cntdot.C triple-helix structure by molecular modeling and vibrational spectroscopy

1993 ◽  
Vol 115 (10) ◽  
pp. 4264-4270 ◽  
Author(s):  
Mohammed Ouali ◽  
Richard Letellier ◽  
Jian Sheng Sun ◽  
Alain Akhebat ◽  
Frederic Adnet ◽  
...  
Keyword(s):  
Molecular Modeling ◽  
Vibrational Spectroscopy ◽  
Triple Helix ◽  
Helix Structure

scholarly journals Changes in collagen stability and folding in lethal perinatal osteogenesis imperfecta. The effect of α1(I)-chain glycine-to-arginine substitutions

1989 ◽  
Vol 261 (1) ◽  
pp. 253-257 ◽  
Author(s):  
A T Baker ◽  
J A M Ramshaw ◽  
D Chan ◽  
W G Cole ◽  
J F Bateman
Keyword(s):  
Osteogenesis Imperfecta ◽  
Molecular Modelling ◽  
Triple Helix ◽  
Structural Abnormality ◽  
Denaturation Temperature ◽  
Collagen Triple Helix ◽  
Helix Formation ◽  
Helix Structure ◽  
Collagen Stability

The effect of glycine-to-arginine mutations in the alpha 1 (I)-chain on collagen triple-helix structure in lethal perinatal osteogenesis imperfecta was studied by determination of the helix denaturation temperature and by computerized molecular modelling. Arginine substitutions at glycine residues 391 and 667 resulted in similar small decreases in helix stability. Molecular modelling suggested that the glycine-to-arginine-391 mutant resulted in only a relatively small localized disruption to the helix structure. Thus the glycine-to-arginine substitutions may lead to only a small structural abnormality of the collagen helix, and it is most likely that the over-modification of lysine, poor secretion, increased degradation and other functional sequelae result from a kinetic defect in collagen helix formation resulting from the mutation.

Triple helix formation by .alpha.-oligodeoxynucleotides: A vibrational spectroscopy and molecular modeling study

Biochemistry ◽  
1993 ◽  
Vol 32 (40) ◽  
pp. 10591-10598 ◽  
Author(s):  
Jean Liquier ◽  
Richard Letellier ◽  
Cecile Dagneaux ◽  
Mohammed Ouali ◽  
Francois Morvan ◽  
...  
Keyword(s):  
Molecular Modeling ◽  
Vibrational Spectroscopy ◽  
Triple Helix ◽  
Helix Formation ◽  
Molecular Modeling Study ◽  
Triple Helix Formation ◽  
Modeling Study

scholarly journals A neutral polysaccharide with a triple helix structure from ginger: Characterization and immunomodulatory activity

2021 ◽  
Vol 350 ◽  
pp. 129261
Author(s):  
Xiaolong Yang ◽  
Siqing Wei ◽  
Xiaoming Lu ◽  
Xuguang Qiao ◽  
Jesus Simal-Gandara ◽  
...  
Keyword(s):  
Triple Helix ◽  
Immunomodulatory Activity ◽  
Helix Structure

Bis(β-diketonate) ligands for the synthesis of bimetallic complexes of TiIII, VIII, MnIII and FeIII with a triple-helix structure

1997 ◽  
pp. 1561-1562 ◽  
Author(s):  
Vincent A. Grillo ◽  
Elisa J. Seddon ◽  
Craig M. Grant ◽  
Guillem Aromí ◽  
John C. Bollinger ◽  
...  
Keyword(s):  
Triple Helix ◽  
Bimetallic Complexes ◽  
Helix Structure

scholarly journals Synthesis and Spectroscopic Determination of the Coordination Differences of Cadmium and Zinc Complexes of Dehydroacetic Acid with Pyridine and g-Picoline

2018 ◽  
pp. 81-89
Author(s):  
Erika Martins de Carvalho ◽  
Roselene Ribeiro Riente ◽  
José Daniel Figueroa Villar
Keyword(s):  
Experimental Data ◽  
Molecular Modeling ◽  
Pulse Sequence ◽  
Semiempirical Method ◽  
Octahedral Geometry ◽  
Intermolecular Distance ◽  
Distance Measurements ◽  
Dehydroacetic Acid ◽  
Nmr Techniques

Various complexes of DHA with transition-metal cations are known for their antifungal properties. Here, four novel Zn and Cd complexes were prepared via the substitution of water by pyridine andg-picoline using Zn(DHA)2(H2O)2 (2) and Cd(DHA)2(H2O)2 (3) as starting materials. The products were characterized by IR, UV, elemental analysis, TGA and NMR techniques, including correlation times and intermolecular distance measurements using the NULL pulse sequence. The experimental data were compared to the molecular modeling results using DFT and the semiempirical method PM3, confirming that the pentacoordinated Zn complexes have bipyramidal geometry while the Cd complexes have the expected octahedral geometry. These results show that substitution of Zn by Cd leads to an important modification of the coordination structure, especially when strong ligands are involved.

Triple Helix, Quadruple Helix and Quintuple Helix and How Do Knowledge, Innovation and the Environment Relate To Each Other?

2012 ◽  
pp. 535-565
Author(s):  
Elias Carayannis ◽  
David F.J. Campbell
Keyword(s):  
Sustainable Development ◽  
Triple Helix ◽  
Social Ecology ◽  
Quadruple Helix ◽  
Natural Environments ◽  
Structure Model ◽  
Triple Helix Model ◽  
Knowledge Innovation ◽  
Quintuple Helix ◽  
Helix Structure

This article develops an inter-disciplinary and trans-disciplinary framework of analysis that relates knowledge, innovation and the environment (natural environments) to each other. For that purpose the five-helix structure model of the Quintuple Helix is being introduced. The Triple Helix model, designed by Etzkowitz and Leydesdorff (2000), focuses on the relations of universities, industry and governments. The Quadruple Helix (Carayannis & Campbell, 2009) blends in the perspective of a media-based and culture-based public. The Quintuple Helix finally frames knowledge and innovation in the context of the environment (natural environments). Therefore, the Quintuple Helix can be interpreted as an approach in line with sustainable development and social ecology. “Eco-innovation” and “eco-entrepreneurship” should be processed in such a broader understanding of knowledge and innovation.

Sign in / Sign up

Export Citation Format

Share Document