Intramolecular carbon-carbon bond formation by the anodic oxidation of unsaturated .alpha.-stannyl heteroatom compounds. Synthesis of fluorine containing heterocyclic compounds

1992 ◽  
Vol 114 (19) ◽  
pp. 7594-7595 ◽  
Author(s):  
Junichi Yoshida ◽  
Yuji Ishichi ◽  
Sachihiko Isoe
Keyword(s):  
Anodic Oxidation ◽  
Heterocyclic Compounds ◽  
Bond Formation ◽  
Carbon Bond ◽  
Carbon Carbon Bond ◽  
Heteroatom Compounds

Benzylic Intermolecular Carbon−Carbon Bond Formation by Selective Anodic Oxidation of Dithioacetals

2001 ◽  
Vol 3 (8) ◽  
pp. 1245-1248 ◽  
Author(s):  
Kazuhiro Chiba ◽  
Rikiya Uchiyama ◽  
Shokaku Kim ◽  
Yoshikazu Kitano ◽  
Masahiro Tada
Keyword(s):  
Anodic Oxidation ◽  
Bond Formation ◽  
Carbon Bond ◽  
Carbon Carbon Bond

ChemInform Abstract: Benzylic Intermolecular Carbon-Carbon Bond Formation by Selective Anodic Oxidation of Dithioacetals.

ChemInform ◽  
2010 ◽  
Vol 32 (33) ◽  
pp. no-no
Author(s):  
Kazuhiro Chiba ◽  
Rikiya Uchiyama ◽  
Shokaku Kim ◽  
Yoshikazu Kitano ◽  
Masahiro Tada
Keyword(s):  
Anodic Oxidation ◽  
Bond Formation ◽  
Carbon Bond ◽  
Carbon Carbon Bond

Preparation of heterocyclic compounds via carbon-carbon bond formation catalyzed by an antibody

1996 ◽  
Vol 2 (1) ◽  
pp. 27-31 ◽  
Author(s):  
Tomoya Kitazume ◽  
Takashi Tsukamoto ◽  
Kouichi Murata ◽  
Koutaro Yoshimura
Keyword(s):  
Heterocyclic Compounds ◽  
Bond Formation ◽  
Carbon Bond ◽  
Carbon Carbon Bond

Electrooxidative Cyclization of Hydroquinolyl Alcohols, Hydroquinolylamines, and Dimethyl Aminomalonates

2007 ◽  
Vol 60 (4) ◽  
pp. 236 ◽  
Author(s):  
Mitsuhiro Okimoto ◽  
Takashi Yoshida ◽  
Masayuki Hoshi ◽  
Kazuyuki Hattori ◽  
Masashi Komata ◽  
...  
Keyword(s):  
Intramolecular Cyclization ◽  
Potassium Iodide ◽  
Sodium Methoxide ◽  
Heterocyclic Compounds ◽  
Bond Formation ◽  
Sodium Cyanide ◽  
Carbon Bond ◽  
Carbon Carbon Bond

Several hydroquinolyl alcohols and amines were electrochemically oxidized in methanol in the presence of sodium methoxide and potassium iodide to afford the corresponding intramolecular cyclization products. Furthermore, several amino malonates were electrochemically oxidized to yield the corresponding heterocyclic compounds through an intramolecular carbon–carbon bond formation in the presence of sodium cyanide in methanol.

Carbon Dioxide-Mediated C(sp2)–H Arylation of Primary and Secondary Benzylamines

2018 ◽  
Author(s):  
Mohit Kapoor ◽  
Pratibha Chand-Thakuri ◽  
Michael Young
Keyword(s):  
Carbon Dioxide ◽  
Transition Metal ◽  
Bond Activation ◽  
Bond Formation ◽  
Carbon Bond ◽  
Chelate Effect ◽  
Free Amine ◽  
Carbon Carbon Bond ◽  
New Strategy ◽  
Metal Catalyzed

Carbon-carbon bond formation by transition metal-catalyzed C–H activation has become an important strategy to fabricate new bonds in a rapid fashion. Despite the pharmacological importance of <i>ortho</i>-arylbenzylamines, however, effective <i>ortho</i>-C–C bond formation from C–H bond activation of free primary and secondary benzylamines using Pd<sup>II</sup> remains an outstanding challenge. Presented herein is a new strategy for constructing <i>ortho</i>-arylated primary and secondary benzylamines mediated by carbon dioxide (CO<sub>2</sub>). The use of CO<sub>2</sub> is critical to allowing this transformation to proceed under milder conditions than previously reported, and that are necessary to furnish free amine products that can be directly used or elaborated without the need for deprotection. In cases where diarylation is possible, a chelate effect is demonstrated to facilitate selective monoarylation.

Modern Organic Synthesis in the Laboratory

2008 ◽  
Author(s):  
Jie Jack Li ◽  
Chris Limberakis ◽  
Derek A. Pflum
Keyword(s):  
Organic Chemistry ◽  
Graduate Students ◽  
Organic Synthesis ◽  
Functional Group ◽  
Bond Formation ◽  
Reaction Conditions ◽  
Carbon Bond ◽  
Oxidation Reduction ◽  
Carbon Carbon Bond ◽  
Daunting Task

Searching for reaction in organic synthesis has been made much easier in the current age of computer databases. However, the dilemma now is which procedure one selects among the ocean of choices. Especially for novices in the laboratory, it becomes a daunting task to decide what reaction conditions to experiment with first in order to have the best chance of success. This collection intends to serve as an "older and wiser lab-mate" one could have by compiling many of the most commonly used experimental procedures in organic synthesis. With chapters that cover such topics as functional group manipulations, oxidation, reduction, and carbon-carbon bond formation, Modern Organic Synthesis in the Laboratory will be useful for both graduate students and professors in organic chemistry and medicinal chemists in the pharmaceutical and agrochemical industries.

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