Total synthesis of discorhabdin C: a general aza spiro dienone formation from O-silylated phenol derivatives using a hypervalent iodine reagent

1992 ◽  
Vol 114 (6) ◽  
pp. 2175-2180 ◽  
Author(s):  
Yasuyuki Kita ◽  
Hirofumi Tohma ◽  
Masanao Inagaki ◽  
Kenji Hatanaka ◽  
Takayuki Yakura
Keyword(s):  
Total Synthesis ◽  
Hypervalent Iodine ◽  
Phenol Derivatives

Enantioselective constructions of quaternary carbons and their application to the asymmetric total syntheses of fredericamycin A and discorhabdin A

2007 ◽  
Vol 79 (4) ◽  
pp. 701-713 ◽  
Author(s):  
Yasuyuki Kita ◽  
Hiromichi Fujioka
Keyword(s):  
Natural Products ◽  
Optically Active ◽  
Biologically Active ◽  
Hypervalent Iodine ◽  
Total Syntheses ◽  
Carbon Centers ◽  
Phenol Derivatives ◽  
Fredericamycin A ◽  
Active Natural ◽  
Quaternary Carbons

An efficient enantioselective construction of quaternary carbons including spiro carbons is an area of intense interest due to the importance of these units as components of biologically active natural products. Prominent methods are presented for the synthesis of chiral, nonracemic quaternary carbon centers by (i) stereospecific rearrangement of optically active epoxides, (ii) enzyme-catalyzed resolution, and (iii) hypervalent iodine reagent-induced ipso-substitution of para-substituted phenol derivatives. These methods were applied to the total syntheses of fredericamycin A and discorhabdin A.

ChemInform Abstract: An Intramolecular Cyclization of Phenol Derivatives Bearing Aminoquinones Using a Hypervalent Iodine Reagent.

ChemInform ◽  
2010 ◽  
Vol 27 (20) ◽  
pp. no-no
Author(s):  
Y. KITA ◽  
T. TAKADA ◽  
M. IBARAKI ◽  
M. GYOTEN ◽  
S. MIHARA ◽  
...  
Keyword(s):  
Intramolecular Cyclization ◽  
Hypervalent Iodine ◽  
Phenol Derivatives

Total synthesis of (12R)- and (12S)-12-hydroxymonocerins: stereoselective oxylactonization using a chiral hypervalent iodine(iii) species

RSC Advances ◽  
2013 ◽  
Vol 3 (39) ◽  
pp. 17717 ◽  
Author(s):  
Morifumi Fujita ◽  
Kazuhiro Mori ◽  
Mio Shimogaki ◽  
Takashi Sugimura
Keyword(s):  
Total Synthesis ◽  
Hypervalent Iodine

A synthetic approach to discorhabdin alkaloids: Hypervalent iodine oxidation of -substituted phenol derivatives to azacarbocyclic spirodienones

1989 ◽  
Vol 30 (9) ◽  
pp. 1119-1120 ◽  
Author(s):  
Yasuyuki Kita ◽  
Takayuki Yakura ◽  
Hirofumi Tohma ◽  
Kazumi Kikuchi ◽  
Yasumitsu Tamura
Keyword(s):  
Hypervalent Iodine ◽  
Synthetic Approach ◽  
Phenol Derivatives
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