Spin distributions and molecular conformations in cation radicals of .alpha.,.omega.-bis(9-anthryl)alkanes

1986 ◽  
Vol 90 (21) ◽  
pp. 4958-4961 ◽  
Author(s):  
Atsushi Terahara ◽  
Hiroaki Ohya-Nishiguchi ◽  
Noboru Hirota ◽  
Hiroyuki Higuchi ◽  
Soichi Misumi
Keyword(s):  
Molecular Conformations ◽  
Cation Radicals ◽  
Alpha Omega ◽  
Spin Distributions

ChemInform Abstract: Spin Distributions and Molecular Conformations in Cation Radicals of α,ω-Bis(9-anthryl)alkanes

ChemInform ◽  
1987 ◽  
Vol 18 (7) ◽  
Author(s):  
A. TERAHARA ◽  
H. OHYA-NISHIGUCHI ◽  
N. HIROTA ◽  
H. HIGUCHI ◽  
S. MISUMI
Keyword(s):  
Molecular Conformations ◽  
Cation Radicals ◽  
Spin Distributions

An ENDOR study of spin distributions in octaethylmetalloporphyrin .pi. cation radicals

1989 ◽  
Vol 111 (16) ◽  
pp. 6437-6439 ◽  
Author(s):  
P. O. Sandusky ◽  
A. Salehi ◽  
C. K. Chang ◽  
G. T. Babcock
Keyword(s):  
Cation Radicals ◽  
Spin Distributions

Conformational and substituent effects on spin distributions in porphyrin cation radicals

1990 ◽  
Vol 94 (23) ◽  
pp. 8508-8511 ◽  
Author(s):  
M. W. Renner ◽  
R. J. Cheng ◽  
C. K. Chang ◽  
Jack. Fajer
Keyword(s):  
Substituent Effects ◽  
Cation Radicals ◽  
Spin Distributions ◽  
Porphyrin Cation

ChemInform Abstract: Conformational and Substituent Effects on Spin Distributions in Porphyrin Cation Radicals

ChemInform ◽  
2010 ◽  
Vol 22 (8) ◽  
pp. no-no
Author(s):  
M. W. RENNER ◽  
R.-J. CHENG ◽  
C. K. CHANG ◽  
J. FAJER
Keyword(s):  
Substituent Effects ◽  
Cation Radicals ◽  
Spin Distributions ◽  
Porphyrin Cation

Alpha & Omega of Thinking

1964 ◽  
Vol 9 (5) ◽  
pp. 210-211
Author(s):  
WARD C. HALSTEAD
Keyword(s):  
Alpha Omega

scholarly journals A comparison of orthopaedic surgery and internal medicine perceptions of USMLE Step 1 pass/fail scoring

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Frederick Mun ◽  
Alyssa R. Scott ◽  
David Cui ◽  
Erik B. Lehman ◽  
Seong Ho Jeong ◽  
...  
Keyword(s):  
Internal Medicine ◽  
Extracurricular Activities ◽  
Residency Program ◽  
Medical Schools ◽  
Program Directors ◽  
Program Director ◽  
Personal Knowledge ◽  
Clinical Knowledge ◽  
Alpha Omega ◽  
Residency Program Directors

Abstract Background United States Medical Licensing Examination Step 1 will transition from numeric grading to pass/fail, sometime after January 2022. The aim of this study was to compare how program directors in orthopaedics and internal medicine perceive a pass/fail Step 1 will impact the residency application process. Methods A 27-item survey was distributed through REDCap to 161 U.S. orthopaedic residency program directors and 548 U.S. internal medicine residency program directors. Program director emails were obtained from the American Medical Association’s Fellowship and Residency Electronic Interactive Database. Results We received 58 (36.0%) orthopaedic and 125 (22.8%) internal medicine program director responses. The majority of both groups disagree with the change to pass/fail, and felt that the decision was not transparent. Both groups believe that the Step 2 Clinical Knowledge exam and clerkship grades will take on more importance. Compared to internal medicine PDs, orthopaedic PDs were significantly more likely to emphasize research, letters of recommendation from known faculty, Alpha Omega Alpha membership, leadership/extracurricular activities, audition elective rotations, and personal knowledge of the applicant. Both groups believe that allopathic students from less prestigious medical schools, osteopathic students, and international medical graduates will be disadvantaged. Orthopaedic and internal medicine program directors agree that medical schools should adopt a graded pre-clinical curriculum, and that there should be a cap on the number of residency applications a student can submit. Conclusion Orthopaedic and internal medicine program directors disagree with the change of Step 1 to pass/fail. They also believe that this transition will make the match process more difficult, and disadvantage students from less highly-regarded medical schools. Both groups will rely more heavily on the Step 2 clinical knowledge exam score, but orthopaedics will place more importance on research, letters of recommendation, Alpha Omega Alpha membership, leadership/extracurricular activities, personal knowledge of the applicant, and audition electives.

Regio- and stereoselective dehydrogenation of .alpha.,.omega.-diols catalyzed by a rhodium hydride complex

1986 ◽  
Vol 51 (14) ◽  
pp. 2822-2824 ◽  
Author(s):  
Youichi Ishii ◽  
Katsumi Suzuki ◽  
Takao Ikariya ◽  
Masahiko Saburi ◽  
Sadao Yoshikawa
Keyword(s):  
Hydride Complex ◽  
Alpha Omega

scholarly journals The Effect of Vicinal Difluorination on the Conformation and Potency of Histone Deacetylase Inhibitors

Molecules ◽  
2021 ◽  
Vol 26 (13) ◽  
pp. 3974
Author(s):  
A. Daryl Ariawan ◽  
Flora Mansour ◽  
Nicole Richardson ◽  
Mohan Bhadbhade ◽  
Junming Ho ◽  
...  
Keyword(s):  
Histone Deacetylase ◽  
Histone Deacetylase Inhibitors ◽  
Hdac Inhibitors ◽  
Molecular Conformations ◽  
Fluorinated Analogs ◽  
Selective Agents ◽  
Isoform Selectivity

Histone deacetylase enzymes (HDACs) are potential targets for the treatment of cancer and other diseases, but it is challenging to design isoform-selective agents. In this work, we created new analogs of two established but non-selective HDAC inhibitors. We decorated the central linker chains of the molecules with specifically positioned fluorine atoms in order to control the molecular conformations. The fluorinated analogs were screened against a panel of 11 HDAC isoforms, and minor differences in isoform selectivity patterns were observed.

Sign in / Sign up

Export Citation Format

Share Document