Nuclear magnetic resonance spectroscopy studies of nematic liquid crystals. 2. trans-4-Alkyl(4-cyanophenyl)cyclohexanes

1982 ◽  
Vol 86 (13) ◽  
pp. 2349-2351 ◽  
Author(s):  
M. M. M. Abdoh ◽  
N. C. Shivaprakash ◽  
J. Shashidhara Prasad
Keyword(s):  
Nuclear Magnetic Resonance ◽  
Liquid Crystals ◽  
Magnetic Resonance ◽  
Magnetic Resonance Spectroscopy ◽  
Nuclear Magnetic Resonance Spectroscopy ◽  
Nematic Liquid Crystals ◽  
Resonance Spectroscopy ◽  
Spectroscopy Studies ◽  
Nuclear Magnetic

scholarly journals Forearm P-31 Nuclear Magnetic Resonance Spectroscopy Studies in Oculopharyngeal Muscular Dystrophy

1992 ◽  
Vol 19 (2) ◽  
pp. 174-179 ◽  
Author(s):  
Douglas W. Zochodne ◽  
Wilma J. Koopman ◽  
Norbert J. Witt ◽  
Terry Thompson ◽  
Albert A. Driedger ◽  
...  
Keyword(s):  
Nuclear Magnetic Resonance ◽  
Magnetic Resonance ◽  
Muscular Dystrophy ◽  
Magnetic Resonance Spectroscopy ◽  
Nuclear Magnetic Resonance Spectroscopy ◽  
Resonance Spectroscopy ◽  
Oculopharyngeal Muscular Dystrophy ◽  
Mean Values ◽  
Spectroscopy Studies ◽  
Nuclear Magnetic

ABSTRACT:Five siblings with autosomal dominant oculopharyngeal muscular dystrophy (OPMD) underwent P-31 Nuclear Magnetic Resonance Spectroscopy studies of forearm flexor muscles. Mean values of PCr/(PCr + Pi) in the patients were reduced (p = 0.01) and pH elevated (p = 0.02) in resting muscle when compared to controls. During exercise PCr/(PCr + Pi) fell quickly to values less than controls (p < 0.0001) despite submaximal exercise output and developed exercise-induced acidosis which exceeded that of controls (p = 0.05). Acidosis recovered slowly despite relatively normal recovery of PCr/(PCr + Pi) following exercise. Within the patient group, however, one member had normal resting, exercise and recovery values. The studies suggest that OPMD is a more widespread disorder of striated muscle than clinically appreciated. The pattern of findings observed in OPMD differs from those identified in denervation, disuse and mitochondrial myopathy.

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