Raman spectra of hydrated phospholipid bilayers. 2. Water and head-group interactions

1992 ◽  
Vol 96 (1) ◽  
pp. 446-452 ◽  
Author(s):  
Saima Kint ◽  
Paul H. Wermer ◽  
James R. Scherer
Keyword(s):  
Raman Spectra ◽  
Phospholipid Bilayers ◽  
Head Group ◽  
Group Interactions

Interactions of the Antimicrobial Peptide Maculatin 1.1 and Analogues with Phospholipid Bilayers

2011 ◽  
Vol 64 (6) ◽  
pp. 798 ◽  
Author(s):  
David I. Fernandez ◽  
Marc-Antoine Sani ◽  
Frances Separovic
Keyword(s):  
Antimicrobial Peptide ◽  
Solid State Nmr ◽  
Acyl Chain ◽  
Head Group ◽  
Group Interactions ◽  
Bacterial Membranes ◽  
Helical Content ◽  
Lipid System ◽  
Acyl Chains ◽  
Mixed Bilayer

The interactions of the antimicrobial peptide, maculatin 1.1 (GLFGVLAKVAAHVVPAIAEHF-NH2) and two analogues, with model phospholipid membranes have been studied using solid-state NMR and circular dichroism spectroscopy. Maculatin 1.1 and the P15G and P15A analogues displayed minimal secondary structure in water, but with zwitterionic dimyristoylphosphatidylcholine (DMPC) vesicles displayed a significant increase in α-helical content. In mixed phospholipid vesicles of DMPC and anionic dimyristoylphosphatidylglycerol (DMPG), each peptide was highly structured with ~80% α-helical content. In DMPC vesicles, the native peptide displayed moderate head group interaction and significant perturbation of the lipid acyl chains. In DMPC/DMPG vesicles, maculatin 1.1 promoted formation of a DMPG-enriched phase and moderately increased disorder towards acyl chain ends of DMPC in the mixed bilayer. Both analogues showed reduced phospholipid head group interactions with DMPC but displayed significant interactions with the mixed lipid system. These effects support the preferential activity of these antimicrobial peptides for bacterial membranes.

scholarly journals Correction: Effect of lipid head group interactions on membrane properties and membrane-induced cationic β-hairpin folding

2016 ◽  
Vol 18 (38) ◽  
pp. 26998-26998
Author(s):  
Sai J. Ganesan ◽  
Hongcheng Xu ◽  
Silvina Matysiak
Keyword(s):  
Chem Phys ◽  
Membrane Properties ◽  
Head Group ◽  
Group Interactions ◽  
Correction Effect ◽  
Lipid Head Group ◽  
Phys Chem Chem Phys

Correction for ‘Effect of lipid head group interactions on membrane properties and membrane-induced cationic β-hairpin folding’ by Sai J. Ganesan et al., Phys. Chem. Chem. Phys., 2016, 18, 17836–17850.

Raman spectra of hydrated phospholipid bilayers

1990 ◽  
Vol 224 ◽  
pp. 245-257 ◽  
Author(s):  
James R. Scherer ◽  
S. Kint ◽  
B.A. Bolton ◽  
G.F. Bailey
Keyword(s):  
Raman Spectra ◽  
Phospholipid Bilayers

Tail and Head Group Interactions in Phospholipid Monolayers

1996 ◽  
Vol 178 (1) ◽  
pp. 135-143 ◽  
Author(s):  
H. Baltes ◽  
M. Schwendler ◽  
C.A. Helm ◽  
H. Möhwald
Keyword(s):  
Head Group ◽  
Group Interactions ◽  
Phospholipid Monolayers
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