Determination of vanadium-oxygen bond distances and bond orders by Raman spectroscopy

1991 ◽  
Vol 95 (13) ◽  
pp. 5031-5041 ◽  
Author(s):  
Franklin D. Hardcastle ◽  
Israel E. Wachs
Keyword(s):  
Raman Spectroscopy ◽  
Bond Orders ◽  
Oxygen Bond

Determination of molybdenum-oxygen bond distances and bond orders by Raman spectroscopy

1990 ◽  
Vol 21 (10) ◽  
pp. 683-691 ◽  
Author(s):  
Franklin D. Hardcastle ◽  
Israel E. Wachs
Keyword(s):  
Raman Spectroscopy ◽  
Bond Orders ◽  
Oxygen Bond

Determination of Human Coronary Artery Composition by Raman Spectroscopy

Circulation ◽  
1997 ◽  
Vol 96 (1) ◽  
pp. 99-105 ◽  
Author(s):  
James F. Brennan ◽  
Tjeerd J. Römer ◽  
Robert S. Lees ◽  
Anna M. Tercyak ◽  
John R. Kramer ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Coronary Artery ◽  
Human Coronary Artery

Multivariate Analysis Aided Surface-Enhanced Raman Spectroscopy (MVA-SERS) Multiplex Quantitative Detection of Trace Fentanyl in Illicit Drug Mixtures Using a Handheld Raman Spectrometer

2021 ◽  
pp. 000370282110329
Author(s):  
Ling Wang ◽  
Mario O. Vendrell-Dones ◽  
Chiara Deriu ◽  
Sevde Doğruer ◽  
Peter de B. Harrington ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Principal Component ◽  
Surface Enhanced Raman Spectroscopy ◽  
Quantitative Detection ◽  
Least Squares Regression ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Sers Detection ◽  
Current Screening

Recently there has been upsurge in reports that illicit seizures of cocaine and heroin have been adulterated with fentanyl. Surface-enhanced Raman spectroscopy (SERS) provides a useful alternative to current screening procedures that permits detection of trace levels of fentanyl in mixtures. Samples are solubilized and allowed to interact with aggregated colloidal nanostars to produce a rapid and sensitive assay. In this study, we present the quantitative determination of fentanyl in heroin and cocaine using SERS, using a point-and-shoot handheld Raman system. Our protocol is optimized to detect pure fentanyl down to 0.20 ± 0.06 ng/mL and can also distinguish pure cocaine and heroin at ng/mL levels. Multiplex analysis of mixtures is enabled by combining SERS detection with principal component analysis and super partial least squares regression discriminate analysis (SPLS-DA), which allow for the determination of fentanyl as low as 0.05% in simulated seized heroin and 0.10% in simulated seized cocaine samples.

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