Solubilization of Homopolymers by Block Copolymer Micelles in Dilute Solutions: Laser Light Scattering and Viscosity Studies on Micellar Solutions

1995 ◽  
Vol 99 (11) ◽  
pp. 3723-3731 ◽  
Author(s):  
Jose R. Quintana ◽  
Ramiro A. Salazar ◽  
Issa Katime
Keyword(s):  
Light Scattering ◽  
Block Copolymer ◽  
Laser Light ◽  
Laser Light Scattering ◽  
Micellar Solutions ◽  
Dilute Solutions ◽  
Block Copolymer Micelles ◽  
Copolymer Micelles

Light scattering evidence of selective protein fouling on biocompatible block copolymer micelles

Nanoscale ◽  
2012 ◽  
Vol 4 (15) ◽  
pp. 4504 ◽  
Author(s):  
Fernando C. Giacomelli ◽  
Petr Stepánek ◽  
Vanessa Schmidt ◽  
Eliézer Jäger ◽  
Alessandro Jäger ◽  
...  
Keyword(s):  
Light Scattering ◽  
Block Copolymer ◽  
Protein Fouling ◽  
Block Copolymer Micelles ◽  
Copolymer Micelles

scholarly journals Structure of PEP–PEO block copolymer micelles: exploiting the complementarity of small-angle X-ray scattering and static light scattering

2011 ◽  
Vol 44 (3) ◽  
pp. 473-482 ◽  
Author(s):  
Grethe Vestergaard Jensen ◽  
Qing Shi ◽  
María J. Hernansanz ◽  
Cristiano L. P. Oliveira ◽  
G. Roshan Deen ◽  
...  
Keyword(s):  
Light Scattering ◽  
Block Copolymer ◽  
Small Angle ◽  
Static Light Scattering ◽  
Length Scales ◽  
X Ray ◽  
X Ray Scattering ◽  
Block Copolymer Micelles ◽  
Copolymer Micelles ◽  
Poly Ethylene

The structure of large block copolymer micelles is traditionally determined by small-angle neutron scattering (SANS), covering a large range of scattering vectors and employing contrast variation to determine the overall micelle morphology as well as the internal structure on shorter length scales. The present work shows that the same information can be obtained by combining static light scattering (SLS) and small-angle X-ray scattering (SAXS), which provide information on, respectively, large and short length scales. Micelles of a series of block copolymers of poly(ethylene propylene)-b-poly(ethylene oxide) (PEP–PEO) in a 70% ethanol solution are investigated. The polymers have identical PEP blocks of 5.0 kDa and varying PEO blocks of 2.8–49 kDa. The SLS contrasts of PEP and PEO are similar, providing a homogeneous contrast, making SLS ideal for determining the overall micelle morphology. The SAXS contrasts of the two components are very different, allowing for resolution of the internal micelle structure. A core–shell model with a PEP core and PEO corona is fitted simultaneously to the SAXS and SLS data using the different contrasts of the two blocks for each technique. With increasing PEO molecular weight, a transition from cylindrical to spherical micelles is observed. This transition cannot be identified from the SAXS data alone, but only from the SLS data.

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