Introduction to a Novel Approach for Modeling Wax Deposition in Fluid Flows. 1. Taylor−Couette System

2008 ◽  
Vol 47 (3) ◽  
pp. 953-963 ◽  
Author(s):  
Kamran Akbarzadeh ◽  
Mohammed Zougari
2008 ◽  
Author(s):  
Benallal Amine ◽  
Philippe Maurel ◽  
Jean Francois Agassant ◽  
Myriam Darbouret ◽  
Guillaume Avril ◽  
...  

The dynamic sedimentation of large particles including thermal convection gained the significant attentions in various applications using the Direct Numeral Solution (DNS) methods. The current solutions are mainly focused on isothermal suspended particles without the thermal convection separating dissolved particles and enveloping fluids. The systems beside thermal convection having the lack of sufficient investigations like missing the hot and cold elliptic particle in infinity long channels. In this work, we work on two challenges efficient DSN method designing and simulation of elliptic particle in infinity long channel using proposed DNS. The novel approach presented to study and simulates dynamic behaviour of elliptic particle sedimentation using the different settling modes using the Swarm Intelligent (SI) construct Finite Element Fictitious Boundary Method (FEM-FBM) and validates outcomes effectively. The Particle Swarm Optimization (PSO) used as SI to improve the accuracy and efficiency of FEM-FBM model in this work. The PSO based multi-grid FEM-FBM called PFEM-FBM proposed as Direct Numerical Solution (DNS) to simulate and validate fluid flows with thermal convection. The PFEM-FBM method used to understand the progression, energy, and warmth conditions effectively. The re-enactments utilizing PFEM-FBM led to utilizing the three diverse experiments. In the principal case, the relative investigation of cold, hot, and isothermal elliptic particles with thermal convection introduced. In the resulting situation, the estimation of cold elliptic particle improving in an incomprehensibly long channel with its endorsement presented. In the third case, the examination of hot elliptic particle resolve in an incessantly large channel with its support presented. The completion of the study is validated using the simulation outcomes with recent technique at the end.


2015 ◽  
Vol 2015 ◽  
pp. 1-9 ◽  
Author(s):  
William J. McKiver

We review the development of the ellipsoidal vortex model within the field of geophysical fluid dynamics. This vortex model is built on the classical potential theory of ellipsoids and applies to large-scale fluid flows, such as those found in the atmosphere and oceans, where the dynamics are strongly affected by the Earth's rotation. In this large-scale limit the governing equations reduce to the quasi-geostrophic system, where all the dynamics depends on a single scalar field, the potential vorticity, which is a dynamical marker for vortices. The solution of this system is achieved by the inversion of a Poisson equation, that in the case of an ellipsoidal vortex can be solved exactly. From this ellipsoidal solution equilibria have been determined and their stability properties have been studied. Many studies have shown that this ellipsoidal vortex model, while being conceptually simple, is an extremely powerful tool in eliciting some of the fundamental characteristics of turbulent geophysical flows.


1996 ◽  
Vol 324 ◽  
pp. 181-198 ◽  
Author(s):  
S. Ghosh Moulic ◽  
L. S. Yao

The nonlinear evolution of a continuous spectrum of travelling waves resulting from the growth of unstable disturbances in circular Couette flow has been investigated. Numerical solution of the governing integro-differential equations for different initial conditions shows that the equilibrium states of Taylor-vortex, wavy-vortex or spiralvortex flows are not unique, but depend on the initial disturbance. The presence of multiple solutions at a fixed Reynolds number for a given Taylor–Couette geometry has been known since Coles’ seminal contribution in 1965. The current study indicates that the equilibrium state of flows on a stable bifurcation branch is a natural consequence of nonlinear wave resonance and is dependent on the initial conditions. The resulting wavenumber can take any value within an accessible finite band. Since such multiple solutions have also been found numerically for mixed-convection flows and experimentally for several other flows, there is evidence to support the conclusion that a non-uniqueness in the sense of Coles is a generic property for all fluid flows.


Author(s):  
Xiaoping Ouyang ◽  
Boqian Fan ◽  
Huayong Yang ◽  
Rong Qing

The air content in hydraulic transmission fluids significantly reduces bulk modulus of the fluid and causes a drop in the stiffness and response of the hydraulic system. It is consequently very important to monitor the air content in hydraulic fluid for ensuring the hydraulic works in good condition. In this paper, a novel method is presented in which the sampled fluid flows slowly into a vacuum chamber and the pressure of separated air is measured. A model of pressure-time characteristics is established, with moisture content taken into account as well, since moisture is volatile in vacuum and its content in tributyl phosphate (TBP) based fluid is usually too high to be neglected. The model can be simplified, which turned out to be a nonlinear least square problem. Comparison between the measured and calculated value shows that the model matches well with the experimental data.


2019 ◽  
Vol 476 (24) ◽  
pp. 3705-3719 ◽  
Author(s):  
Avani Vyas ◽  
Umamaheswar Duvvuri ◽  
Kirill Kiselyov

Platinum-containing drugs such as cisplatin and carboplatin are routinely used for the treatment of many solid tumors including squamous cell carcinoma of the head and neck (SCCHN). However, SCCHN resistance to platinum compounds is well documented. The resistance to platinum has been linked to the activity of divalent transporter ATP7B, which pumps platinum from the cytoplasm into lysosomes, decreasing its concentration in the cytoplasm. Several cancer models show increased expression of ATP7B; however, the reason for such an increase is not known. Here we show a strong positive correlation between mRNA levels of TMEM16A and ATP7B in human SCCHN tumors. TMEM16A overexpression and depletion in SCCHN cell lines caused parallel changes in the ATP7B mRNA levels. The ATP7B increase in TMEM16A-overexpressing cells was reversed by suppression of NADPH oxidase 2 (NOX2), by the antioxidant N-Acetyl-Cysteine (NAC) and by copper chelation using cuprizone and bathocuproine sulphonate (BCS). Pretreatment with either chelator significantly increased cisplatin's sensitivity, particularly in the context of TMEM16A overexpression. We propose that increased oxidative stress in TMEM16A-overexpressing cells liberates the chelated copper in the cytoplasm, leading to the transcriptional activation of ATP7B expression. This, in turn, decreases the efficacy of platinum compounds by promoting their vesicular sequestration. We think that such a new explanation of the mechanism of SCCHN tumors’ platinum resistance identifies novel approach to treating these tumors.


2020 ◽  
Vol 51 (3) ◽  
pp. 544-560 ◽  
Author(s):  
Kimberly A. Murphy ◽  
Emily A. Diehm

Purpose Morphological interventions promote gains in morphological knowledge and in other oral and written language skills (e.g., phonological awareness, vocabulary, reading, and spelling), yet we have a limited understanding of critical intervention features. In this clinical focus article, we describe a relatively novel approach to teaching morphology that considers its role as the key organizing principle of English orthography. We also present a clinical example of such an intervention delivered during a summer camp at a university speech and hearing clinic. Method Graduate speech-language pathology students provided a 6-week morphology-focused orthographic intervention to children in first through fourth grade ( n = 10) who demonstrated word-level reading and spelling difficulties. The intervention focused children's attention on morphological families, teaching how morphology is interrelated with phonology and etymology in English orthography. Results Comparing pre- and posttest scores, children demonstrated improvement in reading and/or spelling abilities, with the largest gains observed in spelling affixes within polymorphemic words. Children and their caregivers reacted positively to the intervention. Therefore, data from the camp offer preliminary support for teaching morphology within the context of written words, and the intervention appears to be a feasible approach for simultaneously increasing morphological knowledge, reading, and spelling. Conclusion Children with word-level reading and spelling difficulties may benefit from a morphology-focused orthographic intervention, such as the one described here. Research on the approach is warranted, and clinicians are encouraged to explore its possible effectiveness in their practice. Supplemental Material https://doi.org/10.23641/asha.12290687


2015 ◽  
Vol 21 ◽  
pp. 128
Author(s):  
Kaniksha Desai ◽  
Halis Akturk ◽  
Ana Maria Chindris ◽  
Shon Meek ◽  
Robert Smallridge ◽  
...  
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