Complexation of AlIIIby Aromatic Amino Acids in the Gas Phase

2007 ◽  
Vol 46 (16) ◽  
pp. 6413-6419 ◽  
Author(s):  
E. Rezabal ◽  
T. Marino ◽  
J. M. Mercero ◽  
N. Russo ◽  
J. M. Ugalde
2006 ◽  
Vol 257 (1-3) ◽  
pp. 60-69 ◽  
Author(s):  
A. Rimola ◽  
M. Sodupe ◽  
J. Tortajada ◽  
L. Rodríguez-Santiago

Molecules ◽  
2018 ◽  
Vol 23 (1) ◽  
pp. 162 ◽  
Author(s):  
Akimasa Fujihara ◽  
Hikaru Inoue ◽  
Masanobu Sogi ◽  
Michiko Tajiri ◽  
Yoshinao Wada

1995 ◽  
Vol 30 (11) ◽  
pp. 1605-1616 ◽  
Author(s):  
Christine L. Gatlin ◽  
František Tureček ◽  
Tomáš Vaisar

2001 ◽  
Vol 3 (10) ◽  
pp. 1819-1826 ◽  
Author(s):  
L. C. Snoek ◽  
R. T. Kroemer ◽  
M. R. Hockridge ◽  
J. P. Simons

2019 ◽  
Author(s):  
A Craig ◽  
N Kolks ◽  
E Urusova ◽  
BD Zlatopolskiy ◽  
B Neumaier

2018 ◽  
Author(s):  
Golaleh Asghari ◽  
Emad Yuzbashian ◽  
Maryam Zarkesh ◽  
Parvin Mirmiran ◽  
Mehdi Hedayati ◽  
...  

2018 ◽  
Author(s):  
Nidhi Gour ◽  
Bharti Koshti ◽  
Chandra Kanth P. ◽  
Dhruvi Shah ◽  
Vivek Shinh Kshatriya ◽  
...  

We report for the very first time self-assembly of Cysteine and Methionine to discrenible strucutres under neutral condition. To get insights into the structure formation, thioflavin T and Congo red binding assays were done which revealed that aggregates may not have amyloid like characteristics. The nature of interactions which lead to such self-assemblies was purported by coincubating assemblies in urea and mercaptoethanol. Further interaction of aggregates with short amyloidogenic dipeptide diphenylalanine (FF) was assessed. While cysteine aggregates completely disrupted FF fibres, methionine albeit triggered fibrillation. The cytotoxicity assays of cysteine and methionine structures were performed on Human Neuroblastoma IMR-32 cells which suggested that aggregates are not cytotoxic in nature and thus, may not have amyloid like etiology. The results presented in the manuscript are striking, since to the best of our knowledge,this is the first report which demonstrates that even non-aromatic amino acids (cysteine and methionine) can undergo spontaneous self-assembly to form ordered aggregates.


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