Synthesis and Biological Activity of Ester- and Amide-Functionalized Imidazolium Salts and Related Water-Soluble Coinage Metal N-Heterocyclic Carbene Complexes

2012 ◽  
Vol 51 (18) ◽  
pp. 9873-9882 ◽  
Author(s):  
Maura Pellei ◽  
Valentina Gandin ◽  
Marika Marinelli ◽  
Cristina Marzano ◽  
Muhammed Yousufuddin ◽  
...  
Keyword(s):  
Biological Activity ◽  
Water Soluble ◽  
Imidazolium Salts ◽  
Coinage Metal ◽  
Carbene Complexes

The biological activity of glucagon–phospholipid complexes

1983 ◽  
Vol 61 (7) ◽  
pp. 688-691 ◽  
Author(s):  
J. J. Liepnieks ◽  
P. Stoskopf ◽  
E. A. Carrey ◽  
C. Prosser ◽  
R. M. Epand
Keyword(s):  
Biological Activity ◽  
Adenylate Cyclase ◽  
Plasma Membranes ◽  
Bovine Brain ◽  
Water Soluble ◽  
Dipalmitoyl Phosphatidylcholine ◽  
Dimyristoyl Phosphatidylcholine ◽  
Lipoprotein Complex ◽  
Stimulation Of

Glucagon can form water-soluble complexes with phospholipids. The incorporation of glucagon into these lipoprotein particles reduces the biological activity of the hormone. The effect is observed only at temperatures below the phase transition temperature of the phospholipid and results in a decreased stimulation of the adenylate cyclase of rat liver plasma membranes by the lipoprotein complex as compared with the hormone in free solution. Two- to five-fold higher concentrations of glucagon are required for half-maximal stimulation of adenylate cyclase when the hormone is complexed with dimyristoyl phosphatidylcholine, dipalmitoyl phosphatidylcholine, or bovine brain sphingomyelin. A possible role of lipoprotein-associated hormones in the development of insulin resistance is discussed.

Effect of Phenobarbitone Treatment on Vitamin D Metabolism in Mammals

1974 ◽  
Vol 46 (4) ◽  
pp. 433-448 ◽  
Author(s):  
J. Silver ◽  
G. Neale ◽  
G. R. Thompson
Keyword(s):  
Vitamin D ◽  
Biological Activity ◽  
Silicic Acid ◽  
Vitamin D3 ◽  
Water Soluble ◽  
Prolonged Treatment ◽  
Vitamin D Metabolism ◽  
Silicic Acid Chromatography ◽  
Polar Metabolites ◽  
25 Hydroxycholecalciferol

1. The metabolism of radioactive cholecalciferol was studied in control and phenobarbitone-treated rats and pigs. 2. Treatment with phenobarbitone enhanced the appearance in plasma of 25-hydroxycholecalciferol (peak IV on silicic acid chromatography), and of more-polar metabolites (peak V), but not of the most-polar metabolites (peak VI). Peak IV had the chromatographic properties of authentic 25-hydroxycholecalciferol (25-HCC) and had biological activity. 3. There was no effect on the appearance of peaks V and VI in plasma after an injection of radioactive 25-HCC. 4. Treatment with phenobarbitone enhanced the excretion of metabolites of radioactive vitamin D3 in bile. These metabolites were largely water-soluble conjugates of peaks IV, V and VI, which included glucuronides. Peak IV in bile was not identical with 25-HCC. 5. Prolonged treatment with phenobarbitone depleted the tissue radioactivity of rats given radioactive vitamin D3.

Water-Soluble Gold-N-Heterocyclic Carbene Complexes for the Catalytic Homogeneous Acid- and Silver-Free Hydration of Hydrophilic Alkynes

2015 ◽  
Vol 357 (18) ◽  
pp. 3893-3900 ◽  
Author(s):  
Houssein Ibrahim ◽  
Pierre de Frémont ◽  
Pierre Braunstein ◽  
Vincent Théry ◽  
Lionel Nauton ◽  
...  
Keyword(s):  
Water Soluble ◽  
Carbene Complexes ◽  
Homogeneous Acid

scholarly journals Properties, processes and regimes of soil solutions and surface waters

2020 ◽  
Vol 175 ◽  
pp. 12022
Author(s):  
Guriyat Podvolotskaya ◽  
Sergey Belopukhov ◽  
Vitaly Savich ◽  
Andrey Sorokin ◽  
Nikolay Tyutrin
Keyword(s):  
Biological Activity ◽  
Surface Water ◽  
Surface Waters ◽  
Pair Correlation ◽  
Rate Of Change ◽  
Water Soluble ◽  
Soil Solutions ◽  
Different Depths ◽  
Different Soils

Soil solutions and the surface waters are characterized by properties, processes and regimes. Soil solutions of different soils and their surface water have different biological activity and change the activity of dissolved stimulants and inhibitors. The object of the study are soil solutions of the main types of soils obtained in the model experiments with the ratio of soils: water equal to 1:1 and 1: 2, soil solutions and surface water in the flooding of soils with water for 1 week – 3 months. The research method consisted in the assessment of pH, Eh, activity of K, NO3, NH4, Ca, Mg by conventional methods, assessment of concentrations of water-soluble compounds extracted from soils by ionite membranes, in the assessment of biological activity of solutions using biotests. The following is suggested for additional evaluation: the using of cation and anion membranes, determination of interrelation between the properties of waters, equation of pair correlation and multiply regression. The informative value of the gradient of surface water concentrations at different distances from the floor of the reservoir, at different depths of the overwatered soils is shown. The mobility of Ca, Mg, Fe, Mn in soils and the content of their water-soluble forms depends on both pH and Eh, whose influence on the content of water-soluble forms of the considered cations shows the effects of synergy and antagonism. The rate of change in the composition of soil solutions during soil flooding depends on a combination of soil properties, temperature, and duration of flooding. Soil solutions of different soils and their surface waters have differentrates.

scholarly journals Synthesis and biological activity of new bisbenzofuran-imidazolium salts

2020 ◽  
Vol 30 (13) ◽  
pp. 127210 ◽  
Author(s):  
Xue-Quan Wang ◽  
Ping-Ting Ye ◽  
Meng-Jiao Bai ◽  
Wei-Hang Miu ◽  
Zhi-Xin Yang ◽  
...  
Keyword(s):  
Biological Activity ◽  
Imidazolium Salts

Study of a new 3D MOF and its adsorption, slow release and biological activity in water-soluble and oil-soluble pesticides

Polyhedron ◽  
2020 ◽  
Vol 190 ◽  
pp. 114752 ◽  
Author(s):  
Deng Linxin ◽  
Junjie He ◽  
Li Borui ◽  
Wang Nana ◽  
Li Song
Keyword(s):  
Biological Activity ◽  
Slow Release ◽  
Water Soluble

Gold nanoparticles stabilized by PEG-tagged imidazolium salts as recyclable catalysts for the synthesis of propargylamines and the cycloisomerization of γ-alkynoic acids

2020 ◽  
Vol 44 (16) ◽  
pp. 6130-6141 ◽  
Author(s):  
Guillem Fernández ◽  
Laura Bernardo ◽  
Ana Villanueva ◽  
Roser Pleixats
Keyword(s):  
Gold Nanoparticles ◽  
Water Soluble ◽  
Imidazolium Salts ◽  
Recyclable Catalysts

Water-soluble gold nanoparticles prepared in the presence of PEG-tagged tris-imidazolium bromide, containing Au(0) and Au(i) species, are reusable catalysts.

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