Resonance Raman Investigation of the Specific Sensing Mechanism of a Target Molecule by Gas Sensory Proteins

2005 ◽  
Vol 44 (4) ◽  
pp. 758-769 ◽  
Author(s):  
Takehiro Ohta ◽  
Teizo Kitagawa
Keyword(s):  
Resonance Raman ◽  
Target Molecule ◽  
Sensing Mechanism

A new chromo-fluorogenic probe based on BODIPY for NO2 detection in air

2015 ◽  
Vol 51 (9) ◽  
pp. 1725-1727 ◽  
Author(s):  
L. Alberto Juárez ◽  
Ana M. Costero ◽  
Margarita Parra ◽  
Salvador Gil ◽  
Félix Sancenón ◽  
...  
Keyword(s):  
Carbonyl Group ◽  
Target Molecule ◽  
Sensing Mechanism ◽  
Fluorogenic Probe ◽  
Fluorescent Chemodosimeter ◽  
No2 Detection

A new fluorescent chemodosimeter for detecting NO2 has been synthesized. The sensing mechanism is based on the regeneration of the carbonyl group induced by the target molecule. This reaction gives rise to both colorimetric and fluorescent changes. A LOD of 0.1 ppm has been determined.

Oxygen-Sensing Mechanism of HemAT fromBacillussubtilis:  A Resonance Raman Spectroscopic Study

2004 ◽  
Vol 126 (46) ◽  
pp. 15000-15001 ◽  
Author(s):  
Takehiro Ohta ◽  
Hideaki Yoshimura ◽  
Shiro Yoshioka ◽  
Shigetoshi Aono ◽  
Teizo Kitagawa
Keyword(s):  
Spectroscopic Study ◽  
Oxygen Sensing ◽  
Resonance Raman ◽  
Raman Spectroscopic ◽  
Sensing Mechanism ◽  
Raman Spectroscopic Study

Characterization of mutant ß-Catenin as a target molecule for antigen-specific immunotherapy in Wilms tumors

2004 ◽  
Vol 216 (03) ◽  
Author(s):  
D Ehrlich ◽  
M Thome ◽  
M von Knebel Doeberitz ◽  
R Koesters
Keyword(s):  
Specific Immunotherapy ◽  
Target Molecule

A Short Synthesis of (+)-Brefeldin C via Enantioselective Radical Hydroalkynylation

2019 ◽  
Author(s):  
Lars Gnägi ◽  
Severin Vital Martz ◽  
Daniel Meyer ◽  
Robin Marc Schärer ◽  
Philippe Renaud
Keyword(s):  
Total Synthesis ◽  
Natural Product ◽  
Oxidation State ◽  
Single Step ◽  
Radical Process ◽  
Target Molecule ◽  
Short Synthesis ◽  
The One

<div><div><div><div><p>A very concise total synthesis of (+)-brefeldin C starting from 2-furanylcyclopentene is described. This approach is based on an unprecedented enantioselective radical hydroalkynylation process to introduce the two cyclopentane stereocenters in a single step. The use of a furan substituent allows to achieve a high trans diastereoselectivity during the radical process and it contains the four carbon atoms C1–C4 of the natural product in an oxidation state closely related to the one of the target molecule. The eight-step synthesis require six product purifications and it provides (+)-brefeldin C in 18% overall yield.</p></div></div></div></div>

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