Transmetalation of tetranuclear copper complexes. 9. Stoichiometry and kinetics of transmetalation of (.mu.4-O)[NCu]4X6 complexes by M(NS)2 reagents in aprotic solvents

1986 ◽  
Vol 25 (22) ◽  
pp. 3899-3903 ◽  
Author(s):  
Geoffrey Davies ◽  
Mohamed A. El-Sayed ◽  
Ahmed El-Toukhy
Keyword(s):  
Copper Complexes ◽  
Aprotic Solvents ◽  
Kinetics Of

Kinetics of ligand exchange reactions of lead and copper complexes of ethylenedinitrilotetraacetate and propylenedinitrilotetraacetate

1967 ◽  
Vol 39 (12) ◽  
pp. 1358-1366 ◽  
Author(s):  
James D. Carr ◽  
Kenneth. Torrance ◽  
Calvin J. Cruz ◽  
Charles N. Reilley
Keyword(s):  
Ligand Exchange ◽  
Copper Complexes ◽  
Exchange Reactions ◽  
Kinetics Of

Cytotoxic Activity of Cu/TiO2 Nanoparticles on Uterine-Cervical Cancer Cells

2020 ◽  
Vol 20 (12) ◽  
pp. 7289-7298
Author(s):  
Samuel González-García ◽  
Aída Hamdan-Partida ◽  
Emma Elisa Ortiz Islas ◽  
Miguel Ángel Zavala Sánchez ◽  
Julia Pêrez Ramos ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Hela Cells ◽  
Copper Complexes ◽  
Sol Gel ◽  
Uterine Cervical Cancer ◽  
Degraded Dna ◽  
Scanning Calorimetry ◽  
Biological Interest ◽  
Cervical Cancer Cells ◽  
Kinetics Of

Nanoparticles based on metal oxides serve as carrier matrices for molecules of biological interest. In this work, we used different copper complexes that were coupled to TiO2 nanoparticles. Nanoparticles were prepared with the sol–gel method. The Cu/TiO2 nanoparticles were characterized through ultraviolet-visible and Fourier transform infrared spectroscopy, differential scanning calorimetry, thermogravimetric analysis, nitrogen physisorption analysis, and scanning electron microscopy. Their biological activity was determined through DNA degradation and their cytotoxic effect on HeLa cells. The Cu/TiO2 nanoparticles presented a pore size between 2 and 6 nm, the size of nanoparticles agglomerates was between 100 and 500 nm. The nanoparticles of Cu/TiO2 degraded DNA starting at 15 min. The half maximal inhibitory concentration in HeLa cells depends on the used cooper complexes, the kinetics of cell death is of first order. Results revealed that these nanoparticles could be applied in uterine-cervical cancer treatment.

Sign in / Sign up

Export Citation Format

Share Document