Additions and Corrections - Synthesis and Antibody-Labeling Studies with the p-Isothiocyanatobenzene Derivatives of 1,2-Dicarba-closo-dodecaborane(12) and the Dodecahydro-7,8-dicarba-nido-undecaborate(1-) Ion for Neutron-Capture Therapy of Human Cancer. Crystal and Molecular Structure of Cs+[nido-7-(p-C6H4NCS)-9-I-7-8-C2B9H11]-

1986 ◽  
Vol 25 (9) ◽  
pp. 1512-1512
Author(s):  
Eugene Mizusawa ◽  
Michael Thompson ◽  
M. Hawthorne
Keyword(s):  
Molecular Structure ◽  
Neutron Capture ◽  
Crystal And Molecular Structure ◽  
Human Cancer ◽  
Neutron Capture Therapy ◽  
Antibody Labeling ◽  
Derivatives Of

The Meisenheimer Rearrangement in Heterocyclic Synthesis. IV. Derivatives of the 2H,6H-1,5,4-Benzodioxazocine and 7H-1,6,5-Benzodioxazonine Ring Systems: X-Ray Crystal Structure of 10-Methoxy-5-methyl-7-phenyl-2,3,4,5-tetrahydro-7H-1,6,5-benzodioxazonine

1988 ◽  
Vol 41 (3) ◽  
pp. 293 ◽  
Author(s):  
JB Bremner ◽  
EJ Browne ◽  
LM Engelhardt ◽  
IWK Gunawardana ◽  
AH White
Keyword(s):  
Molecular Structure ◽  
Crystal Structure ◽  
Crystal And Molecular Structure ◽  
Ring System ◽  
Heterocyclic Synthesis ◽  
Rearrangement Product ◽  
Ring Systems ◽  
X Ray ◽  
Derivatives Of ◽  
Moderate Yield

Meisenheimer rearrangement of the N-oxides (4) derived from a series of 5-aryl-4-methyl-2,3,4,5-tetrahydro-1,4-benzoxazepines (3) gave rise to eight derivatives (5) of the new 2H,6H-1,5,4-benzodioxazocine ring system. Reaction of 9-methoxy-5-methyl-6-phenyl-3,4,5,6- tetrahydro-2H-1,5-benzoxazocine (6) with 3-chloroperoxybenzoic acid gave an unstable N-oxide (7). A Meisenheimer rearrangement product from (7), 10-methoxy-5-methyl-7-phenyl-2,3,4,5-tetrahydro-7 H-1,6,5- benzodioxazonine (8), the first example of this ring system, was isolated directly in moderate yield on oxidation of (6) with cooling. The crystal and molecular structure of (8) has been determined by X-ray crystallographic methods.

Sign in / Sign up

Export Citation Format

Share Document