Levels and Potential Sources of Decabromodiphenyl Ethane (DBDPE) and Decabromodiphenyl Ether (DecaBDE) in Lake and Marine Sediments in Sweden

2010 ◽  
Vol 44 (6) ◽  
pp. 1987-1991 ◽  
Author(s):  
Niklas Ricklund ◽  
Amelie Kierkegaard ◽  
Michael S. McLachlan
Keyword(s):  
Marine Sediments ◽  
Decabromodiphenyl Ether ◽  
Potential Sources ◽  
Decabromodiphenyl Ethane

Mass balance of decabromodiphenyl ethane and decabromodiphenyl ether in a WWTP

Chemosphere ◽  
2009 ◽  
Vol 74 (3) ◽  
pp. 389-394 ◽  
Author(s):  
Niklas Ricklund ◽  
Amelie Kierkegaard ◽  
Michael S. McLachlan ◽  
Cajsa Wahlberg
Keyword(s):  
Mass Balance ◽  
Decabromodiphenyl Ether ◽  
Decabromodiphenyl Ethane

Comparative hepatic microsomal biotransformation of selected PBDEs, including decabromodiphenyl ether, and decabromodiphenyl ethane flame retardants in Arctic marine-feeding mammals

2011 ◽  
Vol 30 (7) ◽  
pp. 1506-1514 ◽  
Author(s):  
Melissa A. McKinney ◽  
Rune Dietz ◽  
Christian Sonne ◽  
Sylvain De Guise ◽  
Karl Skirnisson ◽  
...  
Keyword(s):  
Flame Retardants ◽  
Decabromodiphenyl Ether ◽  
Decabromodiphenyl Ethane

Decabromodiphenyl ethane and decabromodiphenyl ether in Swedish background air

Chemosphere ◽  
2012 ◽  
Vol 86 (3) ◽  
pp. 264-269 ◽  
Author(s):  
Anna-Lena Egebäck ◽  
Ulla Sellström ◽  
Michael S. McLachlan
Keyword(s):  
Decabromodiphenyl Ether ◽  
Background Air ◽  
Decabromodiphenyl Ethane

Australasian Huperzia as potential sources of Huperzine A and B

Planta Medica ◽  
2009 ◽  
Vol 75 (09) ◽  
Author(s):  
WH Lim ◽  
JQG Goodger ◽  
AR Field ◽  
JAM Holtum ◽  
IE Woodrow
Keyword(s):  
Huperzine A ◽  
Potential Sources

PHENOLIC METABOLITES OF DL-NORGESTREL: A METHOD FOR THE REMOVAL OF 1-HYDROXYLATED METABOLITES, POTENTIAL SOURCES OF PHENOLIC ARTIFACTS

1974 ◽  
Vol 76 (4) ◽  
pp. 789-800 ◽  
Author(s):  
Samuel F. Sisenwine ◽  
Ann L. Liu ◽  
Hazel B. Kimmel ◽  
Hans W. Ruelius
Keyword(s):  
Urinary Metabolites ◽  
Ion Exchange Resin ◽  
Gas Chromatography Mass Spectrometry ◽  
Phenolic Metabolites ◽  
Hydroxylated Metabolites ◽  
Analytical Work ◽  
Potential Sources ◽  
Alkaline Conditions ◽  
Artifact Formation ◽  
Work Up

ABSTRACT The identification of 1β-hydroxynorgestrel among the urinary metabolites of dl-norgestrel and the facile transformation of this compound under mild alkaline conditions to a potentially oestrogenic phenol provide an experimental basis for the conclusion advanced by others that the oestrogens present in the urine of subjects treated with synthetic progestens are artifacts formed during analytical work-up. A method has been devised which eliminates 1-hydroxylated metabolites as potential sources of phenolic artifacts. This method is based on the reduction by NaBH4 of the 1-hydroxy-4-en-3-one grouping in the A ring thereby excluding the possibility of aromatization during later fractionation on a basic ion exchange resin that separates neutral from phenolic metabolites. In the urines of women treated with 14C-dl-nogestrel, only 0.17–0.27% of the dose is found to have phenolic properties when this method is used. Two of the phenolic metabolites, 18-homoethynyloestradiol and 16β-hydroxy-18-homoethynyloestradiol, are present in amounts smaller than 0.01 % of the dose. Without the reduction steps the percentages are noticeably higher, indicating artifact formation under alkaline conditions. Similar results were obtained with urines from African Green Monkeys (Cercopithecus Aethiops) that had been dosed with 14C-dl-norgestrel. Radiolabelled 18-homoethynyloestradiol and 16β-hydroxy-18-homoethynyloestradiol were isolated from monkey urine and their identity confirmed by gas chromatography-mass spectrometry.

The Improvement of Paclitaxel Cytotoxicity using Nanocellulose based Nature Resources

2019 ◽  
Vol 1 (1) ◽  
pp. 7
Author(s):  
R Nahrowi ◽  
A Setiawan ◽  
Noviany Noviany ◽  
I Sukmana ◽  
S D Yuwono
Keyword(s):  
Drug Delivery ◽  
Drug Release ◽  
Natural Resources ◽  
Cell Viability ◽  
Cancer Cells ◽  
Drug Delivery System ◽  
Target Cell ◽  
Mitotic Cycle ◽  
Potential Sources ◽  
Local Accumulation

Paclitaxel is one of the cancer drugs that often used. These drug kills cancer cells byinhibiting mitotic cycle. The efficiency of paclitaxel is increased by the use ofnanomaterials as a carrier of paclitaxel. Nanomaterials can enhance encapsulationefficiency, improve the drug release to the target cell following nanomaterialdegradation, and improve local accumulation of drug in the cell through endocytosisreceptor. Nanomaterial that often used forencapsulation of paclitaxel is a polymerderived from natural resources such as cellulose. The advantages of cellulose as acarrier of paclitaxel are nontoxic, biodegradable, and very abundant from varioussources. One of the potential sources of cellulose for drug delivery system is cassavabaggase.Keywords: Paclitaxel, encapsulation, cell viability, nanocellulose

The large superpredators’ teeth from Middle Triassic of Poland

2013 ◽  
Vol 2 (1) ◽  
pp. 91-94 ◽  
Author(s):  
Dawid Surmik ◽  
Tomasz Brachaniec
Keyword(s):  
Marine Sediments ◽  
Middle Triassic ◽  
Morphological Features ◽  
Marine Reptiles

ABSTRACT An unusual large teeth, finding from time to time in marine sediments of Muschelkalk, Silesia, Poland indicate the superpredators occurrence. According to size and morphological features the teeth are similar to archosaurs or giant marine reptiles.

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