Time Trends and the Influence of Age and Gender on Serum Concentrations of Perfluorinated Compounds in Archived Human Samples

2009 ◽  
Vol 43 (6) ◽  
pp. 2131-2136 ◽  
Author(s):  
Line S. Haug ◽  
Cathrine Thomsen ◽  
Georg Becher
1983 ◽  
Vol 65 (6) ◽  
pp. 665-667 ◽  
Author(s):  
A. M. De Bruijn ◽  
F. C. A. Geers ◽  
R. S. A. J. Hylkema ◽  
R. Vermeeren ◽  
A. Hofman

1. Serum concentrations of IgG and IgM were measured in 87 hypertensive and 87 normotensive subjects, matched for age and gender, and selected from the same general population. 2. No significant differences between these two groups were found, in contrast to some previous reports. 3. The reasons for this discrepancy are discussed.


1997 ◽  
Vol 27 (2) ◽  
pp. 467-472 ◽  
Author(s):  
JAN NEELEMAN ◽  
SIMON WESSELY

Background. The legal definition of suicide in England and Wales (E & W) gives rise to a high proportion of open verdicts and an underestimated suicide rate. We examined whether the ratio between open and suicide verdicts in E & W has changed between 1974 and 1991 and whether it varies according to coroners' qualifications.Methods. Temporal changes of the ratio of open and suicide verdicts were examined using logistic regression adjusting for confounders such as changing age and gender distributions of suicide victims and the methods they use.Results. Adjusted for age at death and suicide method, the ratio between open and suicide verdicts had, over successive 3-year time periods, increased with a factor 1·21 (95% CI 1·20–1·23) for male and 1·15 (95% CI 1·14–1·17) for female deaths. Medical coroners were 1·25 (1·08–1·44) times more likely than non-medical coroners to return open rather than suicide verdicts.Conclusions. As a likely result of factors in the death registration system, the ratio between open and suicide verdicts has increased substantially in E & W since the early 70s. In 1990 it was higher than in any other comparable country. This has important implications for comparisons of time trends in suicide between E & W and other countries.


2018 ◽  
Vol 100 (4) ◽  
pp. 295-300 ◽  
Author(s):  
JH Shulin ◽  
J Aizhen ◽  
SM Kuo ◽  
WB Tan ◽  
KY Ngiam ◽  
...  

Introduction The annual incidence of thyroid cancer is known to vary with geographic area, age and gender. The increasing incidence of thyroid cancer has been attributed to increase in detection of micropapillary subtype, among other factors. The aim of the study was to investigate time trends in the incidence of thyroid cancer in Singapore, an iodine-sufficient area. Materials and methods Data retrieved from the Singapore National Cancer Registry on all thyroid cancers that were diagnosed from 1974 to 2013 were reviewed. We studied the time trends of thyroid cancer based on gender, race, pathology and treatment modalities where available. Results The age-standardised incidence rate of thyroid cancer increased to 5.6/100,000 in 2013 from 2.5/100,000 in 1974. Thyroid cancer appeared to be more common in women, with a higher incidence in Chinese and Malays compared with Indians. Papillary carcinoma is the most common subtype. The percentage of papillary microcarcinoma has remained relatively stable at around 38% of all papillary cancers between 2007 and 2013. Although the incidence of thyroid cancer has increased since 1974, the mortality rate has remained stable. Conclusion This trend of increase in incidence of thyroid cancer in Singapore compares with other published series; however, the rise seen was not solely due to micropapillary type. Thyroid cancer was also more common in Chinese and Malays compared with Indians for reasons that needs to be studied further.


2019 ◽  
Vol 08 (06) ◽  
pp. 463-469 ◽  
Author(s):  
Vasileios Lempesis ◽  
Daniel Jerrhag ◽  
Björn E. Rosengren ◽  
Lennart Landin ◽  
Carl Johan Tiderius ◽  
...  

Abstract Background The distal forearm fracture is the most common fracture in children. To allocate health care resources and evaluate if prevention strategies have been successful, it is essential to monitor changes in the epidemiology of common fractures. Methods Our hospital serves a city in which year 2006 included 276,244 inhabitants (49,664 <17 years of age). Through the hospital archives, we identified fractures sustained by individuals younger than 16 years during 2005 and 2006 and compared these with previous collected and published data from the same area and hospital for the period 1950 to 1994. We used official population data to estimate period-specific fracture rates and age and gender standardized time trends. We report rates as number of fractures per 100,000 person-years and changes between periods as rate ratios (RR) with 95% confidence intervals (CIs). Results We identified 521 distal forearm fractures, corresponding to a crude fracture incidence of 564/100,000 person-years (boys 719; girls 401). Age-adjusted fracture incidence was 70% higher in boys than in girls (RR 1.7; 95% CI 1.3–2.3). The age- and gender-adjusted hand fracture incidence was 40% higher in 2005–2006 than in 1950/1955 (RR 1.4; 95% CI 1.2 to 1.8) but no higher than 1993–1994 (RR 1.1; 95% CI 0.9–1.3). Fracture etiology of 2005 to 2006 included sports injuries in 41% and traffic accidents in 11% of the cases, while sports injuries explained 37% and traffic accidents 18% in 1950 to 1955. Conclusion In 2005 to 2006, we found higher rates in boys and higher overall rates compared with the 1950s but no significant differences compared with the rates in 1993 to 1994. Future studies should include patient-specific data to unravel causal factors. Level of evidence This is a Level III b study.


2000 ◽  
Author(s):  
Erika Felix ◽  
Anjali T. Naik-Polan ◽  
Christine Sloss ◽  
Lashaunda Poindexter ◽  
Karen S. Budd

1999 ◽  
Author(s):  
Kirby Gilliland ◽  
Robert E. Schlegel ◽  
Thomas E. Nesthus

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