Express It in Numbers: Efforts to Quantify Engineered Nanoparticles in Environmental Matrices Advance

2012 ◽  
Vol 46 (22) ◽  
pp. 12243-12245 ◽  
Author(s):  
Desiree L. Plata ◽  
P. Lee Ferguson ◽  
Paul Westerhoff
Keyword(s):  
Engineered Nanoparticles ◽  
Environmental Matrices

Imaging of engineered nanoparticles and their aggregates under fully liquid conditions in environmental matrices

2009 ◽  
Vol 43 (13) ◽  
pp. 3335-3343 ◽  
Author(s):  
Karen Tiede ◽  
Steven P. Tear ◽  
Helen David ◽  
Alistair B.A. Boxall
Keyword(s):  
Engineered Nanoparticles ◽  
Environmental Matrices

Where is the nano? Analytical approaches for the detection and quantification of TiO2 engineered nanoparticles in surface waters

2018 ◽  
Vol 5 (2) ◽  
pp. 313-326 ◽  
Author(s):  
Andreas Gondikas ◽  
Frank von der Kammer ◽  
Ralf Kaegi ◽  
Olga Borovinskaya ◽  
Elisabeth Neubauer ◽  
...  
Keyword(s):  
Surface Waters ◽  
Engineered Nanoparticles ◽  
Environmental Matrices ◽  
Natural Nanoparticles ◽  
Analytical Approaches ◽  
Detection And Quantification

Detecting and quantifying engineered nanoparticles (ENPs) in complex environmental matrices requires the distinction between natural nanoparticles (NNPs) and ENPs.

scholarly journals Current status and future direction for examining engineered nanoparticles in natural systems

2014 ◽  
Vol 11 (4) ◽  
pp. 351 ◽  
Author(s):  
Manuel D. Montaño ◽  
Gregory V. Lowry ◽  
Frank von der Kammer ◽  
Julie Blue ◽  
James F. Ranville
Keyword(s):  
Environmental Samples ◽  
Accurate Determination ◽  
Engineered Nanoparticles ◽  
Engineered Nanomaterials ◽  
Current Status ◽  
Environmental Matrices ◽  
New Techniques ◽  
Unique Challenge ◽  
High Background ◽  
Naturally Occurring

Environmental context The detection and characterisation of engineered nanomaterials in the environment is essential for exposure and risk assessment for this emerging class of materials. However, the ubiquitous presence of naturally occurring nanomaterials presents a unique challenge for the accurate determination of engineered nanomaterials in environmental matrices. New techniques and methodologies are being developed to overcome some of these issues by taking advantage of subtle differences in the elemental and isotopic ratios within these nanomaterials. Abstract The increasing manufacture and implementation of engineered nanomaterials (ENMs) will continue to lead to the release of these materials into the environment. Reliably assessing the environmental exposure risk of ENMs will depend highly on the ability to quantify and characterise these materials in environmental samples. However, performing these measurements is obstructed by the complexity of environmental sample matrices, physiochemical processes altering the state of the ENM and the high background of naturally occurring nanoparticles (NNPs), which may be similar in size, shape and composition to their engineered analogues. Current analytical techniques can be implemented to overcome some of these obstacles, but the ubiquity of NNPs presents a unique challenge requiring the exploitation of properties that discriminate engineered and natural nanomaterials. To this end, new techniques are being developed that take advantage of the nature of ENMs to discern them from naturally occurring analogues. This paper reviews the current techniques utilised in the detection and characterisation of ENMs in environmental samples as well as discusses promising new approaches to overcome the high backgrounds of NNPs. Despite their occurrence in the atmosphere and soil, this review will be limited to a discussion of aqueous-based samples containing ENMs, as this environment will serve as a principal medium for the environmental dispersion of ENMs.

Partitioning and stability of engineered ZnO nanoparticles in soil suspensions using flow field-flow fractionation

2007 ◽  
Vol 4 (1) ◽  
pp. 8 ◽  
Author(s):  
Laura J. Gimbert ◽  
Rebecca E. Hamon ◽  
Phil S. Casey ◽  
Paul J. Worsfold
Keyword(s):  
Particle Size ◽  
Flow Field ◽  
Zno Nanoparticles ◽  
Environmental Fate ◽  
Engineered Nanoparticles ◽  
Field Flow Fractionation ◽  
Pore Waters ◽  
Environmental Matrices ◽  
Flow Fractionation

Environmental context. Nanoparticulate materials are increasingly being used as catalysts and lubricants, for pollution control and drug delivery, and in electronics, fabrics, cosmetics and sunscreens. In spite of this growth, information about the fate and toxicity of nanoparticles in the environment is limited, partly due to the lack of techniques capable of measuring nanoparticles in complex environmental matrices. One emerging tool, flow field-flow fractionation, can be used to determine the presence and particle size distribution of engineered nanoparticles, for example in soil pore waters, thereby enhancing our understanding of their environmental fate and impacts. Abstract. This paper reports preliminary results for the determination of engineered ZnO nanoparticles using flow field-flow fractionation (FlFFF). This separation technique was used to determine the particle size distributions (PSDs) of ZnO nanoparticles spiked in soil suspensions. Before FlFFF analysis, the soil was prepared in suspension form, shaken overnight and gravitationally settled to extract the <1-µm fraction. The effect of aging was also investigated using soil samples incubated with known concentrations of ZnO nanoparticles for 7 and 14 days. The results show that FlFFF can be used to determine the PSD of engineered nanoparticles and monitor their partitioning and stability in soil suspensions.

Separation, detection and characterisation of engineered nanoparticles in natural waters using hydrodynamic chromatography and multi-method detection (light scattering, analytical ultracentrifugation and single particle ICP-MS)

2014 ◽  
Vol 11 (4) ◽  
pp. 392 ◽  
Author(s):  
Kim Proulx ◽  
Kevin J. Wilkinson
Keyword(s):  
Light Scattering ◽  
River Water ◽  
Single Particle ◽  
Natural Waters ◽  
Analytical Ultracentrifugation ◽  
Complex Mixture ◽  
Engineered Nanoparticles ◽  
Environmental Matrices ◽  
Hydrodynamic Chromatography ◽  
Icp Ms

Environmental context The effects of engineered nanoparticles on the environment and on human health are difficult to evaluate largely because nanoparticles are so difficult to measure. The main problems are that concentrations are low and the engineered nanoparticles are often difficult to distinguish from the environmental matrices in which they are found. We report a separation technique that facilitates the detection of engineered nanoparticles in natural waters. Abstract Few analytical techniques are presently able to detect and quantify engineered nanoparticles (ENPs) in the environment. The major challenges result from the complex matrices of environmental samples and the low concentrations at which the ENPs are expected to be found. Separation techniques such as asymmetric flow field flow fractionation (AF4) and more recently, hydrodynamic chromatography (HDC) have been used to partly resolve ENPs from their complex environmental matrices. In this paper, HDC was first coupled to light scattering detectors in order to develop a method that would allow the separation and detection of ENPs spiked into a natural water. Size fractionated samples were characterised using off-line detectors including analytical ultracentrifugation (AUC), dynamic light scattering (DLS) and single particle inductively coupled plasma mass spectrometry (SP-ICP-MS). HDC was able to separate a complex mixture of polystyrene, silver and gold nanoparticles (radii of 60, 40, 20 and 10nm) contained within a river water matrix. Furthermore, the feasibility of using HDC coupled to SP-ICP-MS was demonstrated by detecting 4µgL–1 of a 20-nm (radius) nAg in a river water sample.

REVIEW ON RECENT ADVANCES IN ENVIRONMENTAL REMEDIATION AND RELATED TOXICITY OF ENGINEERED NANOPARTICLES

2016 ◽  
Vol 15 (4) ◽  
pp. 923-934 ◽  
Author(s):  
Mohammadreza Kamali ◽  
Ana Paula Duarte Gomes ◽  
Zahra Khodaparast ◽  
Tahereh Seifi
Keyword(s):  
Environmental Remediation ◽  
Engineered Nanoparticles ◽  
Recent Advances

Toxicity and efficacy evaluation of multiple targeted polymalic acid conjugates for triple-negative breast cancer treatment

2020 ◽  
Author(s):  
Lungwani Muungo
Keyword(s):  
Triple Negative ◽  
Growth Factor Receptor ◽  
Engineered Nanoparticles ◽  
Efficacy Evaluation ◽  
Dual Action ◽  
Epidermal Growth ◽  
Laminin 411 ◽  
Immunologic Analysis

Engineered nanoparticles are widely used for delivery of drugs but frequently lack proof of safetyfor cancer patient's treatment. All-in-one covalent nanodrugs of the third generation have beensynthesized based on a poly(β-L-malic acid) (PMLA) platform, targeting human triple-negativebreast cancer (TNBC). They significantly inhibited tumor growth in nude mice by blockingsynthesis of epidermal growth factor receptor, and α4 and β1 chains of laminin-411, the tumorvascular wall protein and angiogenesis marker. PMLA and nanodrug biocompatibility and toxicityat low and high dosages were evaluated in vitro and in vivo. The dual-action nanodrug and singleactionprecursor nanoconjugates were assessed under in vitro conditions and in vivo with multipletreatment regimens (6 and 12 treatments). The monitoring of TNBC treatment in vivo withdifferent drugs included blood hematologic and immunologic analysis after multiple intravenousadministrations. The present study demonstrates that the dual-action nanoconju-gate is highlyeffective in preclinical TNBC treatment without side effects, supported by hematologic andimmunologic assays data. PMLA-based nanodrugs of the Polycefin™ family passed multipletoxicity and efficacy tests in vitro and in vivo on preclinical level and may prove to be optimizedand efficacious for the treatment of cancer patients in the future.

Engineered Nanoparticles with Antimicrobial Property

2018 ◽  
Vol 18 (11) ◽  
pp. 1040-1054 ◽  
Author(s):  
Veliyath Gopi Reshma ◽  
Santhakumar Syama ◽  
Sudhakaran Sruthi ◽  
Sebastain Cherian Reshma ◽  
Nirmal Suma Remya ◽  
...  
Keyword(s):  
Antimicrobial Property ◽  
Engineered Nanoparticles

Coating ligands mediated dynamic formation of natural organic matter (NOM) corona on engineered nanoparticles in environments

2021 ◽  
Author(s):  
Chuan-Wang Yang ◽  
Li Yuan ◽  
Hong-Zhi Zhou ◽  
Xin Zhang ◽  
Guo-Ping Sheng
Keyword(s):  
Organic Matter ◽  
Natural Organic Matter ◽  
Engineered Nanoparticles ◽  
Aquatic Systems ◽  
Solution Interface ◽  
Dynamic Formation

Natural organic matter (NOM) can adsorb onto engineered nanoparticles (ENPs) and form NOM-corona on ENPs-solution interface, thus affecting the performance and ecotoxicity of ENPs in aquatic systems. Nevertheless, the formation...

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