Response To Comment on “Lessons from Endocrine Disruption and Their Application to Other Issues Concerning Trace Organics in the Aquatic Environment”

2006 ◽  
Vol 40 (3) ◽  
pp. 1086-1087 ◽  
Author(s):  
John P. Sumpter ◽  
Andrew C. Johnson
Keyword(s):  
Endocrine Disruption ◽  
Aquatic Environment ◽  
Trace Organics

Antimicrobials and Other Trace Organics in Biosolids: Effects on soil Microbial Processes and Potential for Endocrine Disruption

2011 ◽  
Vol 2011 (4) ◽  
pp. 478-494
Author(s):  
Thomas M. Young ◽  
Temitope Ogunyoku ◽  
Ben Giudice ◽  
Kate Scow ◽  
Inmyoung Park ◽  
...  
Keyword(s):  
Endocrine Disruption ◽  
Microbial Processes ◽  
Soil Microbial ◽  
Trace Organics

scholarly journals Search for the evidence of endocrine disruption in the aquatic environment; Lessons to be learned from joint biological and chemical monitoring in the European project COMPREHEND

2003 ◽  
Vol 75 (11-12) ◽  
pp. 2445-2450 ◽  
Author(s):  
R. I. L. Eggen ◽  
B.-E. Bengtsson ◽  
C. T. Bowmer ◽  
A. A. M. Gerritsen ◽  
Michel Gibert ◽  
...  
Keyword(s):  
Endocrine Disruption ◽  
Aquatic Environment ◽  
Estrogenic Activity ◽  
Natural Populations ◽  
Domestic Wastewater ◽  
Industrial Effluents ◽  
Population Level ◽  
Fish Population ◽  
Genetic Changes ◽  
Chemical Monitoring

Between January 1999 and December 2001, the European Community project COMPREHEND was performed. The overall aim of COMPREHEND was to assess endocrine disruption in the aquatic environment in Europe, consequent to effluent discharge, with emphasis on estrogenic activity. COMPREHEND demonstrated the widespread occurrence of estrogenic effluents across Europe and presented evidence of impacts on a range of wild fish species. Using a variety of bioassays in combination with chemical analytical methods, estrogenic steroids of human origin from domestic wastewater effluents were identified as the most pervasive problem, although alkylphenols may be important estrogenic components of some industrial effluents. New tools have been developed for the identification of estrogenic effluents, and recommendations are made for the improvement of existing techniques. We have shown that individual fish within natural populations may be feminized to varying degrees, but it has not been possible to show, using traditional fish population parameters, that the survival of fish populations is threatened. However, laboratory-based fish life-cycle studies demonstrate the sensitivity of fish to estrogen (and androgen) exposure and how this might lead to complex (and potentially damaging) genetic changes at the population level. New approaches to this problem, utilizing recent advances made in the field of molecular and population genetics, are recommended. Finally, a study of estrogenic and androgenic activity of waste waters during the treatment process has shown that some of the existing wastewater treatment technologies have the potential to eliminate or minimize the hormonal activity of the final effluent.

Alkylphenol ethoxylates and alkylphenols – update information on occurrence, fate and toxicity in aquatic environment

2013 ◽  
Vol 16 (4) ◽  
pp. 762-771 ◽  
Author(s):  
J. Kovarova ◽  
J. Blahova ◽  
L. Divisova ◽  
Z. Svobodova
Keyword(s):  
Human Health ◽  
Endocrine Disruption ◽  
Human Blood ◽  
Mode Of Action ◽  
Aquatic Environment ◽  
Industrial Applications ◽  
Alkylphenol Ethoxylates ◽  
Negative Effects ◽  
Natural Conditions ◽  
Human Blood And Urine

AbstractAlkylphenols and their precursors, alkylphenol etoxylates, are a group of manmade chemicals used mainly as surfactants in domestic and industrial applications worldwide. It has been well established that they have endocrine disruption activity, hepatotoxic, genotoxic and other negative effects on animal and human health. In spite of the effort to reduce their use, they persist in the environment not only in industrial but also in remote regions, and were detected in the variety of natural matrices including air, water, soil as well as food products, and human blood and urine worldwide. This article summarizes their occurrence, fate in natural conditions, and toxicity including mode of action. A subject of our concern was the aquatic environment as the most important reservoir and target of their deleterious impact.

scholarly journals Partitioning, bioavailability and effects of oestrogens and xeno-oestrogens in the aquatic environment

2005 ◽  
Vol 85 (1) ◽  
pp. 1-31 ◽  
Author(s):  
W.J. Langston ◽  
G.R. Burt ◽  
B.S. Chesman ◽  
C.H. Vane
Keyword(s):  
Endocrine Disruption ◽  
Aquatic Environment ◽  
Endocrine Disrupting Chemicals ◽  
Estuarine Sediments ◽  
Food Chains ◽  
Benthic Organisms ◽  
Nonyl Phenol ◽  
Model Compounds ◽  
Endocrine Disrupting

This review provides insights into the distribution and impact of oestrogens and xeno-oestrogens in the aquatic environment and highlights some significant knowledge gaps in our understanding of endocrine disrupting chemicals. Key areas of uncertainty in the assessment of risk include the role of estuarine sediments in mediating the fate and bioavailability of environmental (xeno)oestrogens (notably their transfer to benthic organisms and estuarine food chains), together with evidence for endocrine disruption in invertebrate populations.Emphasis is placed on using published information to interpret the behaviour and effects of a small number of ‘model compounds’ thought to contribute to oestrogenic effects in nature; namely, the natural steroid 17β-oestradiol (E2) and the synthetic hormone 17α-ethinyloestradiol (EE2), together with the alkylphenols octyl- and nonyl-phenol (OP, NP) as oestrogen mimics. Individual sections of the review are devoted to sources and concentrations of (xeno)oestrogens in waterways, sediment partitioning and persistence, bioaccumulation rates and routes, assays and biomarkers of oestrogenicity, and, finally, a synopsis of reproductive and ecological effects in aquatic species.

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