The Petasis Reaction: Microscale Synthesis of a Tertiary Amine Antifungal Analog

2012 ◽  
Vol 89 (6) ◽  
pp. 796-798 ◽  
Author(s):  
Katherine J. Koroluk ◽  
Derek A. Jackson ◽  
Andrew P. Dicks
Keyword(s):  
Tertiary Amine ◽  
Petasis Reaction

scholarly journals Design of ferrocenylseleno-dopamine derivatives to optimize the Fenton-like reaction efficiency and antitumor efficacy

RSC Advances ◽  
2021 ◽  
Vol 11 (41) ◽  
pp. 25477-25483
Author(s):  
Qianya Cheng ◽  
Tong Zhou ◽  
Qing Xia ◽  
Xiulian Lu ◽  
Heng Xu ◽  
...  
Keyword(s):  
Tertiary Amine ◽  
Antitumor Efficacy ◽  
Reaction Efficiency

The tertiary amine in F4b facilitates the Fenton-like reaction to generate toxic ˙OH which induces apoptosis through CDK-2 inactivation.

scholarly journals Electrochemiluminescence Enhancement and Particle Structure Stabilization of Polymer Nanoparticle by Doping Anionic Polyelectrolyte and Cationic Polymer Containing Tertiary Amine Groups and Its Highly Sensitive Immunoanalysis

Processes ◽  
2020 ◽  
Vol 8 (9) ◽  
pp. 1054
Author(s):  
Noor Ul Ain ◽  
Tian-Yu Wang ◽  
Xiao-Ning Wu ◽  
Tong-Hong Wei ◽  
Jing-Shuo Zhang ◽  
...  
Keyword(s):  
Molecular Weight ◽  
Tertiary Amine ◽  
Hepatitis B Surface Antigen ◽  
Particle Diameter ◽  
Cationic Polymer ◽  
Suspension Stability ◽  
Good Precision ◽  
Polymer Nanoparticle ◽  
Anionic Polyelectrolyte ◽  
Amine Groups

A doped polymer nanoparticle (dPNP) of electrochemiluminescence (ECL) was prepared via doping the anionic polyelectrolyte polyacrylic acid (PAA) and the cationic polymer poly-ethyleneimine (PEI) into the polymer nanoparticle (PNP), which was self-assembled by Ru(bpy)32+ derivative-grafted PAA (PAA–Ru) with both cations and anions. The good electrical conductivity of the doped polyelectrolyte PAA enhanced the ECL intensity of PNP to 109.1%, and the involvement of a large number of tertiary amine groups of the doped PEI further enhanced that to 127.3%; meanwhile, doping low-molecular-weight PEI into PNP, while simultaneously doping high-molecular-weight PAA, avoided the precipitation of PAA and PEI, due to interaction of the two oppositely charged polymers; and these also made the self-assembly procedure more effective and the nanoparticle structure more stable than PNP and also led to the production of rich residual PAA chains on the surface of dPNP. The storage results showed that the average hydrated particle diameter kept almost constant (197.5–213.1 nm) during 15-day storage and that the nanoparticles have rich surface charge of −11.47 mV (zeta potential), well suspension stability and good dispersity without detectable aggregation in the solution during the storage. Therefore, the nanoparticle is quite suitable for the antibody labeling, immunoassay and the storage. As a result, a high-sensitive ECL immunoassay approach with good precision, accuracy and selectivity was established and an ultra-low detection limit of 0.049 pg mL−1 (S/N = 3) for magnetic bead-based detection of Hepatitis B surface antigen was observed.

scholarly journals A solvent-dependent chirality-switchable thia-Michael addition to α,β-unsaturated carboxylic acids using a chiral multifunctional thiourea catalyst

2020 ◽  
Vol 11 (21) ◽  
pp. 5572-5576 ◽  
Author(s):  
Noboru Hayama ◽  
Yusuke Kobayashi ◽  
Eriko Sekimoto ◽  
Anna Miyazaki ◽  
Kiyofumi Inamoto ◽  
...  
Keyword(s):  
Carboxylic Acids ◽  
Tertiary Amine ◽  
Michael Addition ◽  
Arylboronic Acid ◽  
Unsaturated Carboxylic Acids

An asymmetric thia-Michael addition of arylthiols to α,β-unsaturated carboxylic acids using a thiourea catalyst that bears arylboronic acid and tertiary amine moieties is reported.

ChemInform Abstract: Highly Efficient Enantioselective Three-Component Synthesis of 2-Amino-4H-chromenes Catalyzed by Chiral Tertiary Amine-Thioureas.

ChemInform ◽  
2012 ◽  
Vol 43 (41) ◽  
pp. no-no
Author(s):  
Gaosheng Yang ◽  
Chongrong Luo ◽  
Xiaolong Mu ◽  
Tingting Wang ◽  
Xin-Yuan Liu
Keyword(s):  
Tertiary Amine ◽  
Highly Efficient

Selective Quaternization of 2-(Dimethylamino)ethyl Methacrylate Residues in Tertiary Amine Methacrylate Diblock Copolymers

2001 ◽  
Vol 34 (5) ◽  
pp. 1148-1159 ◽  
Author(s):  
Vural Bütün ◽  
Steven P. Armes ◽  
Norman C. Billingham
Keyword(s):  
Tertiary Amine ◽  
Diblock Copolymers ◽  
Ethyl Methacrylate
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