Ring-Opening Polymerization of Lactide To Form a Biodegradable Polymer

2008 ◽  
Vol 85 (2) ◽  
pp. 258 ◽  
Author(s):  
Jennifer L. Robert ◽  
Katherine B. Aubrecht
Keyword(s):  
Biodegradable Polymer ◽  
Ring Opening ◽  
Ring Opening Polymerization

Controlling polymer stereochemistry in ring-opening polymerization: a decade of advances shaping the future of biodegradable polyesters

2021 ◽  
Author(s):  
Mathieu J.-L. Tschan ◽  
Régis M. Gauvin ◽  
Christophe M. Thomas
Keyword(s):  
Biodegradable Polymer ◽  
Ring Opening ◽  
Polymer Synthesis ◽  
Ring Opening Polymerization ◽  
Cyclic Esters ◽  
Biodegradable Polyesters ◽  
The Future ◽  
Recent Developments

In this review, we describe recent developments in biodegradable polymer synthesis with a focus on the use of discrete complexes and organocatalysts as active initiators for the stereocontrolled ring-opening polymerization of cyclic esters.

scholarly journals Enzyme-Mediated Ring-Opening Polymerization of Pentadecalactone to Obtain Biodegradable Polymer for Fabrication of Scaffolds for Bone Tissue Engineering

2013 ◽  
Vol 2013 ◽  
pp. 1-10 ◽  
Author(s):  
V. A. Korzhikov ◽  
K. V. Gusevskaya ◽  
E. N. Litvinchuk ◽  
E. G. Vlakh ◽  
T. B. Tennikova
Keyword(s):  
Tissue Engineering ◽  
Molecular Weight ◽  
Phase Separation ◽  
Bone Tissue Engineering ◽  
Bone Tissue ◽  
Biodegradable Polymer ◽  
Ring Opening ◽  
Monomer Concentration ◽  
Ring Opening Polymerization ◽  
Enzyme Ratio

The optimization of enzyme-mediated polymerization of pentadecalactone (PDL) was performed to obtain macromolecular products suitable for generation of 3D cell supports (scaffolds) for bone tissue engineering. Such parameters as temperature, monomer/enzyme ratio, and monomer concentration were studied. The maximum molecular weight of synthesized polymers was about 90,000. Methods allowing the introduction of reactive double bonds into polypentadecalactone (polyPDL) structure were developed. The macroporous matrices were obtained by modification of thermoinduced phase separation method.

A Recommender System for Inverse Design of Polycarbonates and Polyesters

2020 ◽  
Author(s):  
Nathaniel Park ◽  
Dmitry Yu. Zubarev ◽  
James L. Hedrick ◽  
Vivien Kiyek ◽  
Christiaan Corbet ◽  
...  
Keyword(s):  
Ring Opening ◽  
High Performance ◽  
Recommendation System ◽  
Polymeric Materials ◽  
Monomer Conversion ◽  
Design Strategy ◽  
Ring Opening Polymerization ◽  
Inverse Design ◽  
False Negatives ◽  
Accelerate Development

The convergence of artificial intelligence and machine learning with material science holds significant promise to rapidly accelerate development timelines of new high-performance polymeric materials. Within this context, we report an inverse design strategy for polycarbonate and polyester discovery based on a recommendation system that proposes polymerization experiments that are likely to produce materials with targeted properties. Following recommendations of the system driven by the historical ring-opening polymerization results, we carried out experiments targeting specific ranges of monomer conversion and dispersity of the polymers obtained from cyclic lactones and carbonates. The results of the experiments were in close agreement with the recommendation targets with few false negatives or positives obtained for each class.<br>

Bisurea and Bisthiourea H-Bonding Organocatalysts for Ring-Opening Polymerization: Cues for the Catalyst Design

2019 ◽  
Vol 52 (23) ◽  
pp. 9232-9237 ◽  
Author(s):  
Rukshika S. Hewawasam ◽  
U. L. D. Inush Kalana ◽  
Nayanthara U. Dharmaratne ◽  
Thomas J. Wright ◽  
Timothy J. Bannin ◽  
...  
Keyword(s):  
Ring Opening ◽  
Ring Opening Polymerization ◽  
Catalyst Design
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