Rohypnol: Profile of the "Date-Rape Drug"

1998 ◽  
Vol 75 (6) ◽  
pp. 719 ◽  
Author(s):  
Dominick A. Labianca
Keyword(s):  
Date Rape ◽  
Date Rape Drug

Azo Dye-based Optical Probe for the Detection toward Mimic Molecule of Date Rape Drug

2021 ◽  
pp. 106237
Author(s):  
Jiwon Ryu ◽  
Ramalingam Manivannan ◽  
Young-A Son
Keyword(s):  
Azo Dye ◽  
Date Rape ◽  
Optical Probe ◽  
Date Rape Drug

Comparison of N-methyl-2-pyrrolidone (NMP) and the “date rape” drug GHB: behavioral toxicology in the mouse model

2021 ◽  
Author(s):  
Raffaella Arfè ◽  
Sabrine Bilel ◽  
Micaela Tirri ◽  
Paolo Frisoni ◽  
Giovanni Serpelloni ◽  
...  
Keyword(s):  
Mouse Model ◽  
Date Rape ◽  
Behavioral Toxicology ◽  
Date Rape Drug

scholarly journals Rohypnol: More than a Date Rape Drug • 16

1998 ◽  
Vol 43 ◽  
pp. 5-5
Author(s):  
Vaughn I Rickert ◽  
Constance M Wiemann ◽  
Abbey B Berenson
Keyword(s):  
Date Rape ◽  
Date Rape Drug

scholarly journals Development of a fluorescent sensor for an illicit date rape drug – GBL

2013 ◽  
Vol 49 (55) ◽  
pp. 6170 ◽  
Author(s):  
Duanting Zhai ◽  
Bikram Keshari Agrawalla ◽  
Pei Sze Fronia Eng ◽  
Sung-Chan Lee ◽  
Wang Xu ◽  
...  
Keyword(s):  
Date Rape ◽  
Fluorescent Sensor ◽  
Date Rape Drug

scholarly journals A contemporary facet on rohypnol: a date rape drug

2018 ◽  
Vol 4 (1) ◽  
Author(s):  
Navjot Kaur Kanwal
Keyword(s):  
Date Rape ◽  
Date Rape Drug

scholarly journals A contemporary facet on rohypnol: a date rape drug

2018 ◽  
Vol 4 (1) ◽  
Author(s):  
Navjot Kaur Kanwal
Keyword(s):  
Date Rape ◽  
Date Rape Drug

Metabolism of γ-hydroxybutyrate in perfused rat livers

2012 ◽  
Vol 444 (2) ◽  
pp. 333-341 ◽  
Author(s):  
Guo-Fang Zhang ◽  
Sushabhan Sadhukhan ◽  
Rafael A. Ibarra ◽  
Stephanie M. Lauden ◽  
Chia-Ying Chuang ◽  
...  
Keyword(s):  
Date Rape ◽  
Succinic Semialdehyde ◽  
Acetyl Coa ◽  
Parallel Processes ◽  
Multiple Processes ◽  
Isotopomer Analysis ◽  
Pathway Discovery ◽  
Date Rape Drug ◽  
Rat Livers ◽  
Mass Isotopomer

GHB (γ-hydroxybutyrate) is both a neurotransmitter and a drug of abuse (date-rape drug). We investigated the catabolism of this compound in perfused rat livers. Using a combination of metabolomics and mass isotopomer analysis, we showed that GHB is metabolized by multiple processes, in addition to its previously reported metabolism in the citric acid cycle via oxidation to succinate. A substrate cycle operates between GHB and γ-aminobutyrate via succinic semialdehyde. Also, GHB undergoes (i) β-oxidation to glycolyl-CoA+acetyl-CoA, (ii) two parallel processes which remove C-1 or C-4 of GHB and form 3-hydroxypropionate from C-2+C-3+C-4 or from C-1+C-2+C-3 of GHB, and (iii) degradation to acetyl-CoA via 4-phosphobutyryl-CoA. The present study illustrates the potential of the combination of metabolomics and mass isotopomer analysis for pathway discovery.

Development of a fluorescent sensor for illicit date rape drug GHB

2014 ◽  
Vol 50 (22) ◽  
pp. 2904 ◽  
Author(s):  
Duanting Zhai ◽  
Yong Qiao Elton Tan ◽  
Wang Xu ◽  
Young-Tae Chang
Keyword(s):  
Date Rape ◽  
Fluorescent Sensor ◽  
Date Rape Drug
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