Joint Use of Bonding Evolution Theory and QM/MM Hybrid Method for Understanding the Hydrogen Abstraction Mechanism via Cytochrome P450 Aromatase

Ignacio Viciano; Patricio González-Navarrete; Juan Andrés; Sergio Martí

doi:10.1021/ct501030q

Joint Use of Bonding Evolution Theory and QM/MM Hybrid Method for Understanding the Hydrogen Abstraction Mechanism via Cytochrome P450 Aromatase

Journal of Chemical Theory and Computation ◽

10.1021/ct501030q ◽

2015 ◽

Vol 11 (4) ◽

pp. 1470-1480 ◽

Cited By ~ 9

Author(s):

Ignacio Viciano ◽

Patricio González-Navarrete ◽

Juan Andrés ◽

Sergio Martí

Keyword(s):

Cytochrome P450 ◽

Hybrid Method ◽

Hydrogen Abstraction ◽

Evolution Theory ◽

P450 Aromatase ◽

Cytochrome P450 Aromatase

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Closely Related Genes Encode Developmental and Tissue Isoforms of Porcine Cytochrome P450 Aromatase

DNA and Cell Biology ◽

10.1089/dna.1997.16.769 ◽

1997 ◽

Vol 16 (6) ◽

pp. 769-777 ◽

Cited By ~ 41

Author(s):

INHO CHOI ◽

DERYL L. TROYER ◽

DEAN L. CORNWELL ◽

KATHY R. KIRBY-DOBBELS ◽

WERNER R. COLLANTE ◽

...

Keyword(s):

Cytochrome P450 ◽

P450 Aromatase ◽

Cytochrome P450 Aromatase

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Apoptosis in atretic ovarian follicles is associated with selective decreases in messenger ribonucleic acid transcripts for gonadotropin receptors and cytochrome P450 aromatase.

Endocrinology ◽

10.1210/endo.131.4.1396312 ◽

1992 ◽

Vol 131 (4) ◽

pp. 1670-1676 ◽

Cited By ~ 86

Author(s):

J L Tilly ◽

K I Kowalski ◽

D W Schomberg ◽

A J Hsueh

Keyword(s):

Cytochrome P450 ◽

Ribonucleic Acid ◽

Ovarian Follicles ◽

Gonadotropin Receptors ◽

Messenger Ribonucleic Acid ◽

P450 Aromatase ◽

Cytochrome P450 Aromatase

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Characterization of Two Types of Cytochrome P450 Aromatase in the Serial-sex Changing Gobiid Fish, Trimma okinawae

ZOOLOGICAL SCIENCE ◽

10.2108/zsj.21.417 ◽

2004 ◽

Vol 21 (4) ◽

pp. 417-425 ◽

Cited By ~ 46

Author(s):

Yasuhisa Kobayashi ◽

Tohru Kobayashi ◽

Masaru Nakamura ◽

Tomoki Sunobe ◽

Craig E. Morrey ◽

...

Keyword(s):

Cytochrome P450 ◽

Gobiid Fish ◽

P450 Aromatase ◽

Cytochrome P450 Aromatase

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Effect of low dose exposure to the herbicide atrazine and its metabolite on cytochrome P450 aromatase and steroidogenic factor-1 mRNA levels in the brain of premetamorphic bullfrog tadpoles (Rana catesbeiana)

Aquatic Toxicology ◽

10.1016/j.aquatox.2010.12.019 ◽

2011 ◽

Vol 102 (1-2) ◽

pp. 31-38 ◽

Cited By ~ 20

Author(s):

Mark P. Gunderson ◽

Nik Veldhoen ◽

Rachel C. Skirrow ◽

Magnus K. Macnab ◽

Wei Ding ◽

...

Keyword(s):

Cytochrome P450 ◽

Low Dose ◽

Rana Catesbeiana ◽

Mrna Levels ◽

Steroidogenic Factor 1 ◽

P450 Aromatase ◽

Cytochrome P450 Aromatase ◽

Herbicide Atrazine ◽

The Brain

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Molecular cloning of cytochrome P450 aromatase complementary deoxyribonucleic acid from periimplantation porcine and equine blastocysts identifies multiple novel 5'-untranslated exons expressed in embryos, endometrium, and placenta.

Endocrinology ◽

10.1210/endo.137.4.8625924 ◽

1996 ◽

Vol 137 (4) ◽

pp. 1457-1467 ◽

Cited By ~ 24

Author(s):

I Choi ◽

R C Simmen ◽

F A Simmen

Keyword(s):

Cytochrome P450 ◽

Molecular Cloning ◽

Deoxyribonucleic Acid ◽

P450 Aromatase ◽

Cytochrome P450 Aromatase ◽

Complementary Deoxyribonucleic Acid

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Maintenance of Atlantic salmon (Salmo salar) at elevated temperature inhibits cytochrome P450 aromatase activity in isolated ovarian follicles

General and Comparative Endocrinology ◽

10.1016/j.ygcen.2003.11.004 ◽

2004 ◽

Vol 135 (3) ◽

pp. 381-390 ◽

Cited By ~ 36

Author(s):

Marianne Watts ◽

Ned W Pankhurst ◽

Henry R King

Keyword(s):

Cytochrome P450 ◽

Elevated Temperature ◽

Atlantic Salmon ◽

Salmo Salar ◽

Ovarian Follicles ◽

Aromatase Activity ◽

P450 Aromatase ◽

Atlantic Salmon Salmo Salar ◽

Cytochrome P450 Aromatase

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Differential regulation of the expression of cytochrome P450 aromatase, estrogen and androgen receptor subtypes in the brain–pituitary–ovarian axis of the Japanese eel (Anguilla japonica) reveals steroid dependent and independent mechanisms

General and Comparative Endocrinology ◽

10.1016/j.ygcen.2011.11.005 ◽

2012 ◽

Vol 175 (1) ◽

pp. 163-172 ◽

Cited By ~ 33

Author(s):

Shan-Ru Jeng ◽

Jeremy Pasquier ◽

Wen-Shiun Yueh ◽

Guan-Ru Chen ◽

Yan-Horn Lee ◽

...

Keyword(s):

Cytochrome P450 ◽

Androgen Receptor ◽

Differential Regulation ◽

Anguilla Japonica ◽

Japanese Eel ◽

Receptor Subtypes ◽

P450 Aromatase ◽

Steroid Dependent ◽

Cytochrome P450 Aromatase ◽

The Brain

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Molecular characterization and expression of equine testicular cytochrome P450 aromatase

Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression ◽

10.1016/s0167-4781(02)00621-8 ◽

2003 ◽

Vol 1625 (3) ◽

pp. 229-238 ◽

Cited By ~ 6

Author(s):

Gilles-Eric Seralini ◽

Alexey Tomilin ◽

Pierrı̈ck Auvray ◽

Celine Nativelle-Serpentini ◽

Pascal Sourdaine ◽

...

Keyword(s):

Cytochrome P450 ◽

Molecular Characterization ◽

P450 Aromatase ◽

Cytochrome P450 Aromatase

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Maintenance of oestradiol production and expression of cytochrome P450 aromatase enzyme mRNA in long-term serum-free cultures of pig granulosa cells

Reproduction ◽

10.1530/jrf.0.1150067 ◽

1999 ◽

Vol 115 (1) ◽

pp. 67-77 ◽

Cited By ~ 38

Author(s):

H. M. Picton ◽

B. K. Campbell ◽

M. G. Hunter

Keyword(s):

Cytochrome P450 ◽

Granulosa Cells ◽

Serum Free ◽

P450 Aromatase ◽

Cytochrome P450 Aromatase ◽

Oestradiol Production

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Isolation and characterization of two cytochrome P450 aromatase forms in killifish (Fundulus heteroclitus): Differential expression in fish from polluted and unpolluted environments

Aquatic Toxicology ◽

10.1016/j.aquatox.2004.12.007 ◽

2005 ◽

Vol 71 (4) ◽

pp. 371-389 ◽

Cited By ~ 57

Author(s):

Sarah R. Greytak ◽

Denise Champlin ◽

Gloria V. Callard

Keyword(s):

Cytochrome P450 ◽

Differential Expression ◽

Fundulus Heteroclitus ◽

P450 Aromatase ◽

Isolation And Characterization ◽

Cytochrome P450 Aromatase

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