Understanding Solid-Phase Microextraction: Key Factors Influencing the Extraction Process and Trends in Improving the Technique

2012 ◽  
Vol 113 (3) ◽  
pp. 1667-1685 ◽  
Author(s):  
Agata Spietelun ◽  
Adam Kloskowski ◽  
Wojciech Chrzanowski ◽  
Jacek Namieśnik
Keyword(s):  
Solid Phase Microextraction ◽  
Solid Phase ◽  
Extraction Process ◽  
Key Factors ◽  
Factors Influencing

scholarly journals Microfluidic Flow-through SPME Chip for Online Separation and MS Detection of Multiple Analyses in Complex Matrix

Micromachines ◽  
2020 ◽  
Vol 11 (2) ◽  
pp. 120
Author(s):  
Yujun Chen ◽  
Tao Gong ◽  
Cilong Yu ◽  
Xiang Qian ◽  
Xiaohao Wang
Keyword(s):  
Microfluidic Chip ◽  
Solid Phase Microextraction ◽  
Solid Phase ◽  
Sample Pretreatment ◽  
Annular Channel ◽  
Calibration Method ◽  
Extraction Process ◽  
Single Chip ◽  
Calibration Methods ◽  
On Chip

Simplifying tedious sample preparation procedures to improve analysis efficiency is a major challenge in contemporary analytical chemistry. Solid phase microextraction (SPME), a technology developed for rapid sample pretreatment, has flexibility in design, geometry, and calibration strategies, which makes it a useful tool in a variety of fields, especially environmental and life sciences. Therefore, it is important to study the coupling between the microfluidic electrospray ionization (ESI) chip integrated with the solid phase microextraction (SPME) module and the electrospray mass spectrometer (MS). In our previous work, we designed a solid phase microextraction (SPME) module on a microfluidic chip through geometric design. However, automation and calibration methods for the extraction process remain unresolved in the SPME on-chip domain, which will lead to faster and more accurate results. This paper discusses the necessity to design a micromixer structure that can produce different elution conditions on the microfluidic chip. By calculating the channel resistances, the microfluidic chip’s integrated module with the micromixer, SPME, and ESI emitters optimize the geometry structure. We propose the annular channel for SPME to perform the resistances balance of the entire chip. Finally, for SPME on a single chip, this work provides a quantitation calibration method to describe the distribution of the analytes between the sample and the extraction phase before reaching the adsorption equilibrium.

scholarly journals Headspace Solid Phase Microextraction Application for Pesticide Residues in Fruits and Vegetables

2016 ◽  
Vol 2 (2) ◽  
Author(s):  
Abookleesh L Frage , Almrhag M. Omar , Zatout M. Massoud
Keyword(s):  
Sample Preparation ◽  
Solid Phase Microextraction ◽  
Fruits And Vegetables ◽  
High Efficiency ◽  
Solid Phase ◽  
Accurate Determination ◽  
Chemical Properties ◽  
Extraction Process ◽  
Headspace Solid Phase Microextraction

Headspace solid phase microextraction, fundamental& principle with its application on the determination of various pesticides are reviewed in this article. Pesticides extraction as a sample preparation step prior to subsequent analysis is aimed to achieve a reliable and accurate determination of this contaminants residue in food. Fast and high efficiency extraction process with free solvent consumption and overall cost is achieved through headspace solid phase micro extraction. HSPME is an equilibrium process which depends on the physio-chemical properties of the analyte to be extracted. Sample preparation and extraction condition such as fiber coating, temperature, time etc, have a direct impact on the extraction efficiency and sensitivity of headspace technique.

Multivariate optimization of the factors influencing the solid-phase microextraction of pyrethroid pesticides in water

2006 ◽  
Vol 1124 (1-2) ◽  
pp. 148-156 ◽  
Author(s):  
Vanessa Casas ◽  
Maria Llompart ◽  
Carmen García-Jares ◽  
Rafael Cela ◽  
Thierry Dagnac
Keyword(s):  
Solid Phase Microextraction ◽  
Solid Phase ◽  
Multivariate Optimization ◽  
Factors Influencing ◽  
Pyrethroid Pesticides ◽  
Pesticides In Water

scholarly journals Design of the Extraction Process for Characterization of Volatile Profile of Stem Wood by Solid-Phase Microextraction

2019 ◽  
Vol 14 (5) ◽  
pp. 1934578X1984272 ◽  
Author(s):  
Tomáš Bajer ◽  
Jakub Šulc ◽  
Karel Ventura ◽  
Petra Bajerová
Keyword(s):  
Extraction Method ◽  
Solid Phase Microextraction ◽  
Solid Phase ◽  
Extraction Process ◽  
Volatile Components ◽  
Extraction Temperature ◽  
Stem Wood ◽  
Wide Range ◽  
Volatile Profiles

A method for isolation of volatile compounds from samples of stem wood by solid-phase microextraction was developed. The extraction method was optimized using a central composite design approach. Extraction temperature and extraction time were optimized in the ranges of 40°C to 120°C and 10 to 90 minutes, respectively. Final extraction method was combined with GC-MS for separation and identification of volatile components of wood samples of seven tree species, commonly occurring in Central Europe. All of them were deciduous (acacia, alder, beech, elm, larch, maple, and oak). In total 185 organic compounds were identified in volatile profiles of all the samples by the developed method. To facilitate the evaluation of the suitability of the proposed method for extraction of different compound types, all identified compounds were categorized into 16 groups. Percentage of compound groups in volatile profiles of individual wood samples shows that the developed method is suitable for evaluation of a wide range of volatile components from stem wood.

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