scholarly journals The Lipophilic Bullet Hits the Targets: Medicinal Chemistry of Adamantane Derivatives

2013 ◽  
Vol 113 (5) ◽  
pp. 3516-3604 ◽  
Author(s):  
Lukas Wanka ◽  
Khalid Iqbal ◽  
Peter R. Schreiner
Keyword(s):  
Medicinal Chemistry ◽  
Adamantane Derivatives

Direct Radical Functionalization Methods to Access Substituted Adamantanes and Diamondoids

2021 ◽  
Author(s):  
William Weigel ◽  
Hoang Dang ◽  
Abigail Feceu ◽  
David Martin
Keyword(s):  
Medicinal Chemistry ◽  
Adamantane Derivatives ◽  
Catalyst Development ◽  
Stimulus Responsive ◽  
Radical Functionalization

Adamantane derivatives have diverse applications in the fields of medicinal chemistry, catalyst development and nanomaterials, owing to their unique structural, biological and stimulus-responsive properties, among others. The synthesis of substituted...

An Advance In Medicinal Chemistry

1952 ◽  
Vol 8 (5) ◽  
pp. 81-84
Author(s):  
Howard A. Sumner
Keyword(s):  
Medicinal Chemistry

SuFEx Activation with Ca(NTf2)2: A Unified Strategy to Access Sulfamides, Sulfamates and Sulfonamides from S(VI) Fluorides

2020 ◽  
Author(s):  
Subham Mahapatra ◽  
Cristian P. Woroch ◽  
Todd W. Butler ◽  
Sabrina N. Carneiro ◽  
Sabrina C. Kwan ◽  
...  
Keyword(s):  
Room Temperature ◽  
Medicinal Chemistry ◽  
Mild Conditions ◽  
Broad Array

<p><br></p> <p>A method to activate sulfamoyl fluorides, fluorosulfates, and sulfonyl fluorides with calcium triflimide, and DABCO for SuFEx with amines is described. The reaction was applied to a diverse set of sulfamides, sulfamates, and sulfonamides at room temperature under mild conditions. Additionally, we highlight the application of this transformation to parallel medicinal chemistry to generate a broad array of nitrogen-based S(VI) compounds. </p>

SuFEx Activation with Ca(NTf2)2: A Unified Strategy to Access Sulfamides, Sulfamates and Sulfonamides from S(VI) Fluorides

2020 ◽  
Author(s):  
Subham Mahapatra ◽  
Cristian P. Woroch ◽  
Todd W. Butler ◽  
Sabrina N. Carneiro ◽  
Sabrina C. Kwan ◽  
...  
Keyword(s):  
Room Temperature ◽  
Medicinal Chemistry ◽  
Mild Conditions ◽  
Broad Array

<p><br></p> <p>A method to activate sulfamoyl fluorides, fluorosulfates, and sulfonyl fluorides with calcium triflimide, and DABCO for SuFEx with amines is described. The reaction was applied to a diverse set of sulfamides, sulfamates, and sulfonamides at room temperature under mild conditions. Additionally, we highlight the application of this transformation to parallel medicinal chemistry to generate a broad array of nitrogen-based S(VI) compounds. </p>

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