Mechanistic aspects of DNA polymerases: Escherichia coli DNA polymerase I (Klenow fragment) as a paradigm

Steven S. Carroll; Stephen J. Benkovic

doi:10.1021/cr00105a011

Mechanistic aspects of DNA polymerases: Escherichia coli DNA polymerase I (Klenow fragment) as a paradigm

Chemical Reviews ◽

10.1021/cr00105a011 ◽

1990 ◽

Vol 90 (7) ◽

pp. 1291-1307 ◽

Cited By ~ 30

Author(s):

Steven S. Carroll ◽

Stephen J. Benkovic

Keyword(s):

Escherichia Coli ◽

Dna Polymerase ◽

Dna Polymerases ◽

Klenow Fragment ◽

Dna Polymerase I ◽

Polymerase I

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Two DNA Polymerases: HIV Reverse Transcriptase and the Klenow Fragment of Escherichia coli DNA Polymerase I

Cold Spring Harbor Symposia on Quantitative Biology ◽

10.1101/sqb.1993.058.01.056 ◽

1993 ◽

Vol 58 (0) ◽

pp. 495-504 ◽

Cited By ~ 16

Author(s):

T.A. Steitz ◽

S. Smerdon ◽

J. Jager ◽

J. Wang ◽

L.A. Kohlstaedt ◽

...

Keyword(s):

Escherichia Coli ◽

Reverse Transcriptase ◽

Dna Polymerase ◽

Dna Polymerases ◽

Klenow Fragment ◽

Hiv Reverse Transcriptase ◽

Dna Polymerase I ◽

Polymerase I

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Fluorescent oligonucleotides and deoxynucleotide triphosphates: preparation and their interaction with the large (Klenow) fragment of Escherichia coli DNA polymerase I

Biochemistry ◽

10.1021/bi00437a014 ◽

1989 ◽

Vol 28 (11) ◽

pp. 4601-4607 ◽

Cited By ~ 44

Author(s):

Dwayne J. Allen ◽

Paul L. Darke ◽

Stephen J. Benkovic

Keyword(s):

Escherichia Coli ◽

Dna Polymerase ◽

Klenow Fragment ◽

Dna Polymerase I ◽

Polymerase I

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Restoration of the DNA damage resistance of Deinococcus radiodurans DNA polymerase mutants by Escherichia coli DNA polymerase I and Klenow fragment

Mutation Research/DNA Repair ◽

10.1016/0921-8777(94)90064-7 ◽

1994 ◽

Vol 314 (1) ◽

pp. 87-97 ◽

Cited By ~ 24

Author(s):

Pabol D. Gutman ◽

Pinhas Fuchs ◽

Kenneth W. Minton

Keyword(s):

Escherichia Coli ◽

Dna Damage ◽

Dna Polymerase ◽

Deinococcus Radiodurans ◽

Klenow Fragment ◽

Dna Polymerase I ◽

Damage Resistance ◽

Polymerase I ◽

Polymerase Mutants

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The excision of AP sites by the 3'-5' exonuclease activity of the Klenow fragment of Escherichia coli DNA polymerase I

FEBS Letters ◽

10.1016/0014-5793(84)80605-5 ◽

1984 ◽

Vol 178 (2) ◽

pp. 223-227 ◽

Cited By ~ 12

Author(s):

Véronique Bailly ◽

Walter G. Verly

Keyword(s):

Escherichia Coli ◽

Dna Polymerase ◽

Exonuclease Activity ◽

Klenow Fragment ◽

Dna Polymerase I ◽

Ap Sites ◽

Polymerase I

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A single residue in DNA polymerases of the Escherichia coli DNA polymerase I family is critical for distinguishing between deoxy- and dideoxyribonucleotides.

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.92.14.6339 ◽

1995 ◽

Vol 92 (14) ◽

pp. 6339-6343 ◽

Cited By ~ 225

Author(s):

S. Tabor ◽

C. C. Richardson

Keyword(s):

Escherichia Coli ◽

Dna Polymerase ◽

Dna Polymerases ◽

Dna Polymerase I ◽

Polymerase I

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Continuous microspectrophotometric measurement of DNA polymerase activity: application to the Klenow fragment of Escherichia coli DNA polymerase I and human immunodeficiency virus type 1 reverse transcriptase.

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.88.3.1014 ◽

1991 ◽

Vol 88 (3) ◽

pp. 1014-1018 ◽

Cited By ~ 6

Author(s):

J. G. Baillon ◽

N. T. Nashed ◽

J. M. Sayer ◽

D. M. Jerina

Keyword(s):

Escherichia Coli ◽

Human Immunodeficiency Virus ◽

Reverse Transcriptase ◽

Dna Polymerase ◽

Polymerase Activity ◽

Klenow Fragment ◽

Dna Polymerase I ◽

Immunodeficiency Virus ◽

Polymerase I

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A molecular model of the complete three-dimensional structure of the Klenow fragment of Escherichia coli DNA polymerase I: binding of the dNTP substrate and template-primer

Biochemistry ◽

10.1021/bi00126a006 ◽

1992 ◽

Vol 31 (11) ◽

pp. 2879-2886 ◽

Cited By ~ 15

Author(s):

Prem N. S. Yadav ◽

Janardan S. Yadav ◽

Mukund J. Modak

Keyword(s):

Escherichia Coli ◽

Dna Polymerase ◽

Molecular Model ◽

Three Dimensional ◽

Dimensional Structure ◽

Klenow Fragment ◽

Dna Polymerase I ◽

Three Dimensional Structure ◽

Polymerase I

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Utilization of 2′-Deoxy-6-thioguanosine 5′-Triphosphate In DNA Synthesis Catalyzed by DNA Polymerase I Klenow Fragment of Escherichia Coli

Nucleosides and Nucleotides ◽

10.1080/07328319208021150 ◽

1992 ◽

Vol 11 (1) ◽

pp. 23-35 ◽

Cited By ~ 5

Author(s):

Yi-He Ling ◽

J. Arly Nelson ◽

David Farquhar ◽

Kenneth L. Beattie

Keyword(s):

Escherichia Coli ◽

Dna Synthesis ◽

Dna Polymerase ◽

Klenow Fragment ◽

Dna Polymerase I ◽

Polymerase I

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Mechanism of the idling-turnover reaction of the large (Klenow) fragment of Escherichia coli DNA polymerase I.

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.83.2.231 ◽

1986 ◽

Vol 83 (2) ◽

pp. 231-235 ◽

Cited By ~ 13

Author(s):

V. Mizrahi ◽

P. A. Benkovic ◽

S. J. Benkovic

Keyword(s):

Escherichia Coli ◽

Dna Polymerase ◽

Klenow Fragment ◽

Dna Polymerase I ◽

Polymerase I

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Role of the 5´ → 3´ exonuclease and Klenow fragment of Escherichia coli DNA polymerase I in base mismatch repair

Molecular Genetics and Genomics ◽

10.1007/s00438-007-0239-8 ◽

2007 ◽

Vol 278 (2) ◽

pp. 211-220 ◽

Cited By ~ 5

Author(s):

Masaru Imai ◽

Yu-ichiro Tago ◽

Makoto Ihara ◽

Masakado Kawata ◽

Kazuo Yamamoto

Keyword(s):

Escherichia Coli ◽

Mismatch Repair ◽

Dna Polymerase ◽

Klenow Fragment ◽

Dna Polymerase I ◽

Base Mismatch ◽

Polymerase I

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