Thin Walled Imprinted Polymer Beads Featuring Both Uniform and Accessible Binding Sites

2012 ◽  
Vol 24 (15) ◽  
pp. 2909-2919 ◽  
Author(s):  
Mahadeo R. Halhalli ◽  
Eric Schillinger ◽  
Carla S. A. Aureliano ◽  
Börje Sellergren
Keyword(s):  
Binding Sites ◽  
Imprinted Polymer ◽  
Polymer Beads ◽  
Thin Walled

A micro-reactor for preparing uniform molecularly imprinted polymer beads

Lab on a Chip ◽  
2006 ◽  
Vol 6 (2) ◽  
pp. 296 ◽  
Author(s):  
Mohammed Zourob ◽  
Stephan Mohr ◽  
Andrew G. Mayes ◽  
Alexandra Macaskill ◽  
Natalia Pérez-Moral ◽  
...  
Keyword(s):  
Molecularly Imprinted Polymer ◽  
Imprinted Polymer ◽  
Polymer Beads ◽  
Molecularly Imprinted ◽  
Micro Reactor

scholarly journals Imprinted Polymer Beads Loaded with Silver Nanoparticles for Antibacterial Applications

2021 ◽  
Vol 4 (3) ◽  
pp. 2829-2838
Author(s):  
Haiyue Gong ◽  
Solmaz Hajizadeh ◽  
Weifeng Liu ◽  
Lei Ye
Keyword(s):  
Silver Nanoparticles ◽  
Imprinted Polymer ◽  
Polymer Beads

Application of Response Surface Methodology to Synthesize Appropriate Molecularly Imprinted Polymer for Diazinon

2014 ◽  
Vol 605 ◽  
pp. 67-70 ◽  
Author(s):  
Mohsen Rahiminezhad ◽  
Seyed Jamaleddin Shahtaheri ◽  
Mohammad Reza Ganjali ◽  
Abbas Rahimi Rahimi Forushani
Keyword(s):  
Molecular Imprinting ◽  
Molecularly Imprinted Polymer ◽  
Binding Sites ◽  
Capillary Electrochromatography ◽  
Template Molecule ◽  
Imprinted Polymer ◽  
Molecularly Imprinted ◽  
Functional Monomers ◽  
Molecular Imprinting Technology ◽  
Cross Linker

Molecular imprinting technology has become an interesting research area to the preparation of specific sorbent material for environmental and occupational sample preparation techniques (1). In the molecular imprinting technology, specific binding sites have been formed in polymeric matrix, which often have an affinity and selectivity similar to antibody-antigen systems (2). In molecular imprinted technology, functional monomers are arranged in a complementary configuration around a template molecule, then, cross-linker and solvent are also added and the mixture is treated to give a porous material containing nono-sized binding sites. After extraction of the template molecule by washing, vacant imprinted sites will be left in polymer, which are available for rebinding of the template or its structural analogue (3). The stability, convention of preparation and low cost of these materials make them particularly attractive (4). These synthetic materials have been used for capillary electrochromatography (5), chromatography columns (6), sensors (7), and catalyze system (8). Depending on the molecular imprinting approach, different experimental variables such as the type and amounts of functional monomers, porogenic solvent, initiator, monomer to cross-linker ratio, temperature, and etc may alter the properties of the final polymeric materials. In this work, chemometric approach based on Central Composite Design (CCD) was used to design the experiments as well as to find the optimum conditions for preparing appropriate diazinon molecularly imprinted polymer.

scholarly journals Molecularly imprinted polymer beads for nicotine recognition prepared by RAFT precipitation polymerization: a step forward towards multi-functionalities

RSC Advances ◽  
2014 ◽  
Vol 4 (57) ◽  
pp. 30292-30299 ◽  
Author(s):  
Tongchang Zhou ◽  
Lars Jørgensen ◽  
Maria Ahlm Mattebjerg ◽  
Ioannis S. Chronakis ◽  
Lei Ye
Keyword(s):  
Surface Functionalization ◽  
Molecularly Imprinted Polymer ◽  
Precipitation Polymerization ◽  
Imprinted Polymer ◽  
Polymer Beads ◽  
Molecularly Imprinted ◽  
New Applications

Molecularly imprinted polymer beads synthesized by RAFT precipitation polymerization enable versatile surface functionalization and new applications.

Oligonucleotide Imprinting in Aqueous Environment

2002 ◽  
Vol 723 ◽  
Author(s):  
Dolly Batra ◽  
Kenneth J. Shea
Keyword(s):  
Binding Sites ◽  
Mobile Phase ◽  
Water Soluble ◽  
Aqueous Environment ◽  
Imprinted Polymer ◽  
Network Polymer ◽  
Separation Science ◽  
Molecularly Imprinted ◽  
Synthetic Receptor ◽  
Complementary Binding

AbstractThe development of synthetic receptors that recognize nucleotide bases and their derivatives is an important area of research [1-3]. Applications are envisioned in separation science, biosensors, drug therapy and genetic engineering. Previously in this laboratory, we have developed a molecularly imprinted synthetic receptor for 9-ethyladenine (9-EA). The network polymer has an affinity for adenine and its derivatives with an average association constant (Ka) of 75,000 M–1 in CHCl3 [4]. When a 9-EA imprinted polymer was used as the chromatographic support, adenine eluted at 27 minutes using 92.5/5/0/2.5 CH3CN/H2O/CH3CO2H as the mobile phase, while cytosine, guanine and thymine derivatives all eluted close to the void volume (2.0 min). In addition, imprinted polymers have been made with complementary binding sites for cytosine and guanine [5], as well as other nucleotide base analogues [6].The extension of these results to construct robust receptors for oligonucleotides requires fundamental changes in imprinting strategies. Most importantly, since oligonucleotides are water soluble, strategies that employ EGDMA/MAA formulations in organic solvents will need to be replaced with those that do not compromise the interactions between template (the oligo) and functional monomer.Initially, the imprinting of a 2'-deoxyadenosine dimer (1) was attempted. Due to the hydrophilicity of a DNA oligomer, it was difficult to find a suitable organic solvent that would solubilize the oligomers without disrupting the template's interaction with the polymer matrix [7]. To combat the solubility problems and to insure the homogeniety of the polymerization solution, we examined various polymer formulations with organic and/or aqueous-based solvents that would dissolve the template without disrupting these key interactions.

Probing the recognition of molecularly imprinted polymer beads

2011 ◽  
Vol 47 (5) ◽  
pp. 2218-2227 ◽  
Author(s):  
Qendresa Osmani ◽  
Helen Hughes ◽  
Peter McLoughlin
Keyword(s):  
Molecularly Imprinted Polymer ◽  
Imprinted Polymer ◽  
Polymer Beads ◽  
Molecularly Imprinted

Preparation of bovine hemoglobin-imprinted polymer beads via the photografting surface-modified method

2008 ◽  
Vol 3 (4) ◽  
pp. 370-377 ◽  
Author(s):  
Qingqing Gai ◽  
Qiuye Liu ◽  
Wenyou Li ◽  
Xiwen He ◽  
Langxing Chen ◽  
...  
Keyword(s):  
Bovine Hemoglobin ◽  
Imprinted Polymer ◽  
Polymer Beads ◽  
Modified Method ◽  
Surface Modified
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