Downstream Process Synthesis for Biochemical Production of Butanol, Ethanol, and Acetone from Grains: Generation of Optimal and Near-Optimal Flowsheets with Conventional Operating Units

2004 ◽  
Vol 20 (5) ◽  
pp. 1518-1527 ◽  
Author(s):  
J. Liu ◽  
L.T. Fan ◽  
P. Seib ◽  
F. Friedler ◽  
B. Bertok
Keyword(s):  
Process Synthesis ◽  
Downstream Process ◽  
Biochemical Production ◽  
Operating Units

Holistic Approach to Process Retrofitting:  Application to Downstream Process for Biochemical Production of Organics

2006 ◽  
Vol 45 (12) ◽  
pp. 4200-4207 ◽  
Author(s):  
Jiahong Liu ◽  
L. T. Fan ◽  
Paul Seib ◽  
Ferenc Friedler ◽  
Botond Bertok
Keyword(s):  
Holistic Approach ◽  
Downstream Process ◽  
Biochemical Production

Distribution of R- and S-Process Elements in the Galactic Halo

1988 ◽  
Vol 132 ◽  
pp. 501-506
Author(s):  
C. Sneden ◽  
C. A. Pilachowski ◽  
K. K. Gilroy ◽  
J. J. Cowan
Keyword(s):  
Heavy Element ◽  
Galactic Halo ◽  
Low Noise ◽  
Heavy Elements ◽  
Process Synthesis ◽  
Element Abundances ◽  
Halo Stars ◽  
Abundance Patterns ◽  
R Process ◽  
Process Elements

Current observational results for the abundances of the very heavy elements (Z>30) in Population II halo stars are reviewed. New high resolution, low noise spectra of many of these extremely metal-poor stars reveal general consistency in their overall abundance patterns. Below Galactic metallicities of [Fe/H] Ã −2, all of the very heavy elements were manufactured almost exclusively in r-process synthesis events. However, there is considerable star-to-star scatter in the overall level of very heavy element abundances, indicating the influence of local supernovas on element production in the very early, unmixed Galactic halo. The s-process appears to contribute substantially to stellar abundances only in stars more metal-rich than [Fe/H] Ã −2.

Nonlinear and Mixed-Integer Optimization

1995 ◽  
Author(s):  
Christodoulos A. Floudas
Keyword(s):  
Nonlinear Optimization ◽  
Systems Engineering ◽  
Chemical Engineering ◽  
Applied Mathematics ◽  
Linear Optimization ◽  
Mixed Integer ◽  
Process Synthesis ◽  
Synthesis Process ◽  
Integer Optimization ◽  
Mixed Integer Optimization

Filling a void in chemical engineering and optimization literature, this book presents the theory and methods for nonlinear and mixed-integer optimization, and their applications in the important area of process synthesis. Other topics include modeling issues in process synthesis, and optimization-based approaches in the synthesis of heat recovery systems, distillation-based systems, and reactor-based systems. The basics of convex analysis and nonlinear optimization are also covered and the elementary concepts of mixed-integer linear optimization are introduced. All chapters have several illustrations and geometrical interpretations of the material as well as suggested problems. Nonlinear and Mixed-Integer Optimization will prove to be an invaluable source--either as a textbook or a reference--for researchers and graduate students interested in continuous and discrete nonlinear optimization issues in engineering design, process synthesis, process operations, applied mathematics, operations research, industrial management, and systems engineering.

R-phycoerythrin extraction and purification from fresh Gracilaria sp. using thermo-responsive systems

2019 ◽  
Vol 21 (14) ◽  
pp. 3816-3826 ◽  
Author(s):  
Filipa A. Vicente ◽  
Inês S. Cardoso ◽  
Margarida Martins ◽  
Cátia V. M. Gonçalves ◽  
Ana C. R. V. Dias ◽  
...  
Keyword(s):  
Environmental Impact ◽  
Downstream Process ◽  
Responsive Systems ◽  
Extraction And Purification

Besides the good performance, the downstream process based in thermo-responsive systems was shown to be efficient and of lower environmental impact.

scholarly journals Protein L—More Than Just an Affinity Ligand

Processes ◽  
2021 ◽  
Vol 9 (5) ◽  
pp. 874
Author(s):  
Stefan Kittler ◽  
Mihail Besleaga ◽  
Julian Ebner ◽  
Oliver Spadiut
Keyword(s):  
Antibody Fragments ◽  
Downstream Process ◽  
Affinity Ligands ◽  
The Past ◽  
Affinity Ligand ◽  
Recombinant Production ◽  
Production Processes ◽  
Monitoring Tools ◽  
Platform Technology ◽  
Analytical Tools

In the past 30 years, highly specific drugs, known as antibodies, have conquered the biopharmaceutical market. In addition to monoclonal antibodies (mAbs), antibody fragments are successfully applied. However, recombinant production faces challenges. Process analytical tools for monitoring and controlling production processes are scarce and time-intensive. In the downstream process (DSP), affinity ligands are established as the primary and most important step, while the application of other methods is challenging. The use of these affinity ligands as monitoring tools would enable a platform technology to monitor process steps in the USP and DSP. In this review, we highlight the current applications of affinity ligands (proteins A, G, and L) and discuss further applications as process analytical tools.

Bacillus subtilis as a robust host for biochemical production utilizing biomass

2021 ◽  
pp. 1-34
Author(s):  
Seo A. Park ◽  
Shashi Kant Bhatia ◽  
Hyun A. Park ◽  
Seo Yeong Kim ◽  
Pamidimarri D. V. N. Sudheer ◽  
...  
Keyword(s):  
Bacillus Subtilis ◽  
Biochemical Production

SPICE_MARS: A Process Synthesis Framework for Membrane-Assisted Reactive Separations

2021 ◽  
Author(s):  
Mohammed Sadaf Monjur ◽  
Salih Emre Demirel ◽  
Jianping Li ◽  
M. M. Faruque Hasan
Keyword(s):  
Process Synthesis
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