Optimization of Rosmarinic Acid Production by Lavandula vera MM Plant Cell Suspension in a Laboratory Bioreactor

2008 ◽  
Vol 21 (2) ◽  
pp. 394-396 ◽  
Author(s):  
Atanas I. Pavlov ◽  
Milen I. Georgiev ◽  
Ivan N. Panchev ◽  
Mladenka P. Ilieva
2006 ◽  
Vol 61 (3-4) ◽  
pp. 241-244 ◽  
Author(s):  
Milen Georgiev ◽  
Sonya Kuzeva ◽  
Atanas Pavlov ◽  
Elena Kovacheva ◽  
Mladenka Ilieva

The influence of elicitation on rosmarinic acid biosynthesis by Lavandula vera MM cell suspension culture was investigated using vanadyl sulfate as an abiotic elicitor. It was established that 12 h after treatment with 25 mg/l vanadyl sulfate the rosmarinic acid production was increased up to 3.92 g/l (2.8 times higher compared to the control cultivation). No significant amounts of rosmarinic acid were detected in the culture medium in comparison with its intracellular content. However, it was observed that the extracellular content of rosmarinic acid is 3.3 times higher compared to the control variant (4 h after treatment at elicitor concentration 25 mg/l).


PLoS Biology ◽  
2008 ◽  
Vol 6 (12) ◽  
pp. e302 ◽  
Author(s):  
Milos Tanurdzic ◽  
Matthew W Vaughn ◽  
Hongmei Jiang ◽  
Tae-Jin Lee ◽  
R. Keith Slotkin ◽  
...  

2017 ◽  
Vol 133 (1) ◽  
pp. 137-146 ◽  
Author(s):  
Tiago Fidemann ◽  
Gabriela Aparecida de Araujo Pereira ◽  
Tárik Reis Heluy ◽  
Rodrigo Boccoli Gallego ◽  
Mônica Rosa Bertão ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document