Facile Co-Assembly Process to Generate Core–Shell Nanoparticles with Functional Protein Corona

2014 ◽  
Vol 15 (3) ◽  
pp. 948-956 ◽  
Author(s):  
Nisaraporn Suthiwangcharoen ◽  
Tao Li ◽  
Laying Wu ◽  
Heidi B. Reno ◽  
Preston Thompson ◽  
...  
Catalysts ◽  
2021 ◽  
Vol 11 (6) ◽  
pp. 730
Author(s):  
Erik Sarnello ◽  
Tao Li

Enzyme immobilization techniques are widely researched due to their wide range of applications. Polymer–protein core–shell nanoparticles (CSNPs) have emerged as a promising technique for enzyme/protein immobilization via a self-assembly process. Based on the desired application, different sizes and distribution of the polymer–protein CSNPs may be required. This work systematically studies the assembly process of poly(4-vinyl pyridine) and bovine serum albumin CSNPs. Average particle size was controlled by varying the concentrations of each reagent. Particle size and size distributions were monitored by dynamic light scattering, ultra-small-angle X-ray scattering, small-angle X-ray scattering and transmission electron microscopy. Results showed a wide range of CSNPs could be assembled ranging from an average radius as small as 52.3 nm, to particles above 1 µm by adjusting reagent concentrations. In situ X-ray scattering techniques monitored particle assembly as a function of time showing the initial particle growth followed by a decrease in particle size as they reach equilibrium. The results outline a general strategy that can be applied to other CSNP systems to better control particle size and distribution for various applications.


2015 ◽  
Vol 494 (1) ◽  
pp. 430-444 ◽  
Author(s):  
Behrang Shiri Varnamkhasti ◽  
Hosniyeh Hosseinzadeh ◽  
Morteza Azhdarzadeh ◽  
Seyed Yaser Vafaei ◽  
Mehdi Esfandyari-Manesh ◽  
...  

ACS Nano ◽  
2020 ◽  
Vol 14 (10) ◽  
pp. 12708-12718 ◽  
Author(s):  
Martina Schroffenegger ◽  
Nikolaus S. Leitner ◽  
Giulia Morgese ◽  
Shivaprakash N. Ramakrishna ◽  
Max Willinger ◽  
...  

2015 ◽  
Vol 3 (2) ◽  
pp. 265-278 ◽  
Author(s):  
Usawadee Sakulkhu ◽  
Morteza Mahmoudi ◽  
Lionel Maurizi ◽  
Geraldine Coullerez ◽  
Margarethe Hofmann-Amtenbrink ◽  
...  

We showed that protein corona is strongly dependent on the coating of the material.


2012 ◽  
Vol 27 (1) ◽  
pp. 95-101
Author(s):  
Shi-Bin LIU ◽  
Chun-Ying YANG ◽  
Zhong-Lin ZHANG ◽  
Dong-Hong DUAN ◽  
Xiao-Gang HAO ◽  
...  

2013 ◽  
Vol 20 (28) ◽  
pp. 3488-3499 ◽  
Author(s):  
Yon Jung ◽  
Hwanbum Lee ◽  
Jae Kim ◽  
Eun Koo ◽  
Keun Oh ◽  
...  

2021 ◽  
Vol 330 ◽  
pp. 129364
Author(s):  
Jinhua Wang ◽  
Jiamin Wu ◽  
Yuping Zhang ◽  
Xia Zhou ◽  
Ziwei Hu ◽  
...  

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