The Nature of Protein Interactions Governing Globular Protein–Polymer Block Copolymer Self-Assembly

2014 ◽  
Vol 15 (4) ◽  
pp. 1248-1258 ◽  
Author(s):  
Christopher N. Lam ◽  
Minkyu Kim ◽  
Carla S. Thomas ◽  
Dongsook Chang ◽  
Gabriel E. Sanoja ◽  
...  
Keyword(s):  
Block Copolymer ◽  
Protein Interactions ◽  
Self Assembly ◽  
Globular Protein ◽  
Protein Polymer ◽  
Polymer Block

scholarly journals Effect of polymer chemistry on globular protein–polymer block copolymer self-assembly

2014 ◽  
Vol 5 (17) ◽  
pp. 4884-4895 ◽  
Author(s):  
Dongsook Chang ◽  
Christopher N. Lam ◽  
Shengchang Tang ◽  
Bradley D. Olsen
Keyword(s):  
Phase Transitions ◽  
Block Copolymer ◽  
Self Assembly ◽  
Polymer Chemistry ◽  
Protein Polymer ◽  
Polymer Conjugate ◽  
Cubic Phases ◽  
Polymer Interactions ◽  
Nanostructure Control ◽  
Polymer Block

Changing polymer chemistry in protein–polymer conjugate block copolymers results in the formation of previously unobserved cubic phases and changes in protein–polymer interactions that create large shifts in phase transitions, providing a powerful tool for nanostructure control.

scholarly journals Topology effects on protein–polymer block copolymer self-assembly

2019 ◽  
Vol 10 (14) ◽  
pp. 1751-1761 ◽  
Author(s):  
Takuya Suguri ◽  
Bradley D. Olsen
Keyword(s):  
Block Copolymer ◽  
Self Assembly ◽  
Fluorescent Protein ◽  
Microphase Separation ◽  
Chain Structure ◽  
Synthetic Polymer ◽  
Red Fluorescent Protein ◽  
Protein Polymer ◽  
Ordering Transitions ◽  
Polymer Block

Bioconjugates made of the model red fluorescent protein mCherry and synthetic polymer blocks show that topology, i.e. the BA, BA2, ABA and ABC chain structure of the block copolymers, where B represents the protein and A and C represent polymers, has a significant effect on ordering transitions and the type and size of nanostructures formed during microphase separation.

scholarly journals Predicting Protein–Polymer Block Copolymer Self-Assembly from Protein Properties

2019 ◽  
Vol 20 (10) ◽  
pp. 3713-3723 ◽  
Author(s):  
Aaron Huang ◽  
Justin M. Paloni ◽  
Amy Wang ◽  
Allie C. Obermeyer ◽  
Hursh V. Sureka ◽  
...  
Keyword(s):  
Block Copolymer ◽  
Self Assembly ◽  
Protein Polymer ◽  
Protein Properties ◽  
Polymer Block

Amphiphilic block copolymer poly(lactic acid)-block -(glycidylazide polymer)-block -polystyrene: synthesis and self-assembly

2017 ◽  
Vol 66 (7) ◽  
pp. 1037-1043 ◽  
Author(s):  
Guoping Li ◽  
Haoxue Dong ◽  
Menghui Liu ◽  
Min Xia ◽  
Chunpeng Chai ◽  
...  
Keyword(s):  
Lactic Acid ◽  
Block Copolymer ◽  
Self Assembly ◽  
Amphiphilic Block Copolymer ◽  
Poly Lactic Acid ◽  
Copolymer Poly ◽  
Polymer Block

Secondary structure drives self-assembly in weakly segregated globular protein–rod block copolymers

2020 ◽  
Vol 11 (17) ◽  
pp. 3032-3045
Author(s):  
Helen Yao ◽  
Kai Sheng ◽  
Jialing Sun ◽  
Shupeng Yan ◽  
Yingqin Hou ◽  
...  
Keyword(s):  
Secondary Structure ◽  
Block Copolymers ◽  
Self Assembly ◽  
Globular Protein ◽  
Effective Segregation ◽  
Polymer Block

Imparting secondary structure to the polymer block can drive self-assembly in globular protein–helix block copolymers, increasing the effective segregation strength between blocks with weak or no repulsion.

Topological Effects on Globular Protein-ELP Fusion Block Copolymer Self-Assembly

2014 ◽  
Vol 25 (5) ◽  
pp. 729-738 ◽  
Author(s):  
Guokui Qin ◽  
Matthew J. Glassman ◽  
Christopher N. Lam ◽  
Dongsook Chang ◽  
Eric Schaible ◽  
...  
Keyword(s):  
Block Copolymer ◽  
Self Assembly ◽  
Globular Protein
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