Synthesis and Characterization of Collagen Grafted Poly(hydroxybutyrate–valerate) (PHBV) Scaffold for Loading of Bovine Serum Albumin Capped Silver (Ag/BSA) Nanoparticles in the Potential Use of Tissue Engineering Application

2013 ◽  
Vol 15 (1) ◽  
pp. 423-435 ◽  
Author(s):  
Rotimi A. Bakare ◽  
Chandra Bhan ◽  
Dharmaraj Raghavan
Keyword(s):  
Tissue Engineering ◽  
Bovine Serum Albumin ◽  
Serum Albumin ◽  
Bovine Serum ◽  
Engineering Application ◽  
Synthesis And Characterization ◽  
Tissue Engineering Application ◽  
Potential Use

Fabrication of BSA Loaded Poly (Caprolactone) (PCL)/Hydroxyapatite (HA) Composite Microsphere for Tissue Engineering Application

2014 ◽  
Vol 1030-1032 ◽  
pp. 82-85
Author(s):  
Mad Jin Rashid ◽  
Naznin Sultana ◽  
Hamdan Salehhuddin
Keyword(s):  
Tissue Engineering ◽  
Bovine Serum Albumin ◽  
Serum Albumin ◽  
Bovine Serum ◽  
Engineering Application ◽  
Double Emulsion ◽  
Average Diameter ◽  
Tissue Engineering Application ◽  
Poly Caprolactone

In this study, PCL microsphere has been synthesised using the double emulsion technique and a freeze dry technique. Bovine Serum Albumin (BSA) was added as a model protein and Hydroxyapatite (HA) to enhance osteoconductivity properties of the microsphere. Poly (caprolactone) (PCL)-based microspheres were synthesized and characterized. Microspheres were produced with 5%, 10%, and 15% (w/v) PCL solution (30mL) by dissolving different amounts of PCL in dichloromethane (DCM). Microspheres produced from 5% (w/v) PCL concentration had an average diameter of 100 – 120 μm. Bovine serum albumin (BSA) (0.04% w/v) and 10% w/w of HA powder were added into the microspheres produced from 5% (w/v) PCL concentration. The microsphere was then characterized using different techniques and in vitro release study of BSA was conducted. Prepared microsphere showed good potential for bone tissue engineering.

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