Chemical Modification of Wheat-Protein-Based Natural Polymers:  Formation of Polymer Networks with Alkoxysilanes To Modify Molecular Motions and Enhance the Material Performance

2007 ◽  
Vol 8 (6) ◽  
pp. 1881-1889 ◽  
Author(s):  
Xiaoqing Zhang ◽  
My Dieu Do ◽  
Alex Bilyk
2014 ◽  
Vol 2014 ◽  
pp. 1-11 ◽  
Author(s):  
Alka Lohani ◽  
Garima Singh ◽  
Shiv Sankar Bhattacharya ◽  
Anurag Verma

Polymers have always been valuable excipients in conventional dosage forms, also have shown excellent performance into the parenteral arena, and are now capable of offering advanced and sophisticated functions such as controlled drug release and drug targeting. Advances in polymer science have led to the development of several novel drug delivery systems. Interpenetrating polymer networks (IPNs) have shown superior performances over the conventional individual polymers and, consequently, the ranges of applications have grown rapidly for such class of materials. The advanced properties of IPNs like swelling capacity, stability, biocompatibility, nontoxicity and biodegradability have attracted considerable attention in pharmaceutical field especially in delivering bioactive molecules to the target site. In the past few years various research reports on the IPN based delivery systems showed that these carriers have emerged as a novel carrier in controlled drug delivery. The present review encompasses IPNs, their types, method of synthesis, factors which affects the morphology of IPNs, extensively studied IPN based drug delivery systems, and some natural polymers widely used for IPNs.


1996 ◽  
Vol 33 (10) ◽  
pp. 1459-1477 ◽  
Author(s):  
Xiao-yin Hong ◽  
Han-bao Feng

2010 ◽  
Vol 29 (2) ◽  
pp. 169 ◽  
Author(s):  
Ružica Jovanović-Malinovska ◽  
Maja Cvetkovska ◽  
Slobodanka Kuzmanova ◽  
Christo Tsvetanov ◽  
Eleonora Winkelhausen

Hydrogel matrices were designed as hybrid networks of poly(ethylene oxide) (PEO) with natural polymers,alginate or chitosan by UV irradiation. The networks were formulated in the single-stage procedure inwhich the alginate or chitosan were added to the crosslinking reaction solution of PEO, and two-stage procedure,with additional chemical crosslinking of alginate or chitosan. Double-layer hydrogels composed of PEOhydrogel core with entrapped cells and outer natural hydrogel layer were also synthesized. The hydrogels werecharacterized by gel fraction yield and degree of equilibrium swelling as well as by rheological measurements.The production of ethanol by immobilized Saccharomyces cerevisiae was used to test the suitability of the synthesizedhybrid hydrogels to serve as carriers for cell immobilization. The presence of cells affected the mechanicalproperties and the structure of the polymer networks. The best system for immobilization was found to bethe PEO/alginate/Ca, which exhibited high mechanical strength (G′, 830; GF, 93; ESH2O, 15) without affectingthe metabolic functions of the cells. The maximum ethanol yield was 0.42 g/g corresponding to 82 % of thetheoretical yield.


2020 ◽  
Vol 2020 ◽  
pp. 1-12
Author(s):  
Seblewongel Petros ◽  
Tamrat Tesfaye ◽  
Million Ayele

Hydrogels are hydrophilic polymer networks that absorb any kind of liquid including biological fluids. Natural polymers and their derivatives along with synthetic polymers are used to form the hydrogels. Networks that constitute the hydrogels are created by the crosslinking of either synthesized polymers starting from monomers or already developed polymers. Crosslinking can be developed either physically if secondary intermolecular forces are involved or chemically in which a covalent bond between polymeric chains is created. Gelatins are natural driven protein polymers. One of the main biopolymers used for producing hydrogels is gelatin. Gelatin has a very wide application other than hydrogels. In this review, hydrogels and their property and synthesis mechanism, as well as their application in biomedical along with gelatin chemistry and application, are reviewed. Due to its nonimmunogenicity, nontoxicity, low cost, and high availability gelatin-based hydrogels could find applications in drug delivery carrier, bioink, transdermal therapy, wound healing, and tissue repair. The beneficiation of gelatin can result in their sustainable conversion into high-value biomaterials on the proviso of the existence or development of cost-effective, sustainable technologies for converting this biopolymer into useful bioproducts.


2019 ◽  
Vol 15 (4) ◽  
pp. 371-381 ◽  
Author(s):  
Amalnath John ◽  
Wen Zhong

Hydrogels are three-dimensional polymer networks capable of absorbing and holding a large amount of water. They have a wide range of biomedical applications including drug carriers, biosensors, tissue scaffolds and wound dressings owning to their innate resemblance to the living tissue. Recently biodegradable and renewable natural polymers, especially nanocellulose, have gained immense attention in the development of hydrogels for biomedical applications. This review provides a brief analysis of the various nanocellulosic materials used in the fabrication of hydrogels for various biomedical applications. Recent developments in high performance hydrogels based on nanocellulose, including self-healing, highly tough and/or stretchable and 3D printable hydrogels will also be covered in this review.


Molecules ◽  
2021 ◽  
Vol 26 (9) ◽  
pp. 2608
Author(s):  
Nishith A. Chudasama ◽  
Rosy Alphons Sequeira ◽  
Kinjal Moradiya ◽  
Kamalesh Prasad

Among the various natural polymers, polysaccharides are one of the oldest biopolymers present on the Earth. They play a very crucial role in the survival of both animals and plants. Due to the presence of hydroxyl functional groups in most of the polysaccharides, it is easy to prepare their chemical derivatives. Several polysaccharide derivatives are widely used in a number of industrial applications. The polysaccharides such as cellulose, starch, chitosan, etc., have several applications but due to some distinguished characteristic properties, seaweed polysaccharides are preferred in a number of applications. This review covers published literature on the seaweed polysaccharides, their origin, and extraction from seaweeds, application, and chemical modification. Derivatization of the polysaccharides to impart new functionalities by chemical modification such as esterification, amidation, amination, C-N bond formation, sulphation, acetylation, phosphorylation, and graft copolymerization is discussed. The suitability of extraction of seaweed polysaccharides such as agar, carrageenan, and alginate using ionic solvent systems from a sustainability point of view and future prospects for efficient extraction and functionalization of seaweed polysaccharides is also included in this review article.


Polimery ◽  
2021 ◽  
Vol 66 (1) ◽  
pp. 11-20
Author(s):  
Grażyna K Korbecka-Glinka ◽  
Maria Wiśniewska-Wrona ◽  
Ewa Kopania

Biopolymers from a group of polysaccharides are used in treatments enhancing sowing material of crops due to their physical and chemical properties, susceptibility to chemical modification, biodegradability and high bioactivity. Natural polymers, such as: chitosan, alginian, celulose, galaktoglucomannans, lignin and gellan gum, can be used as binders in seed coating or carriers of active substances and microorganisms. Moreover, biopolymers contained in the seed coatings and seed dressings can protect germinating seeds from unfavorable influence of environment and pathogens.


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