Gelatin-Based Microcarriers as Embryonic Stem Cell Delivery System in Bone Tissue Engineering:  An in-Vitro Study

2007 ◽  
Vol 8 (3) ◽  
pp. 825-832 ◽  
Author(s):  
S. Tielens ◽  
H. Declercq ◽  
T. Gorski ◽  
E. Lippens ◽  
E. Schacht ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Stem Cell ◽  
Embryonic Stem Cell ◽  
Bone Tissue Engineering ◽  
Bone Tissue ◽  
Embryonic Stem ◽  
In Vitro Study ◽  
Cell Delivery ◽  
Stem Cell Delivery

Nanoapatitic composite scaffolds for stem cell delivery and bone tissue engineering

2018 ◽  
pp. 211-230
Author(s):  
Hockin H.K. Xu ◽  
Mike D. Weir ◽  
Liang Zhao ◽  
Jennifer L. Moreau ◽  
Dwayne D. Arola ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Stem Cell ◽  
Bone Tissue Engineering ◽  
Bone Tissue ◽  
Cell Delivery ◽  
Composite Scaffolds ◽  
Stem Cell Delivery

Amine-functionalized Single-walled Carbon Nanotube/Polycaprolactone Electrospun Scaffold for Bone Tissue Engineering: in vitro Study

2019 ◽  
Vol 20 (9) ◽  
pp. 1869-1882 ◽  
Author(s):  
Hadi Tohidlou ◽  
Seyedeh Sara Shafiei ◽  
Shahsanam Abbasi ◽  
Mitra Asadi-Eydivand ◽  
Mehrnoosh Fathi-Roudsari
Keyword(s):  
Tissue Engineering ◽  
Carbon Nanotube ◽  
Bone Tissue Engineering ◽  
Bone Tissue ◽  
In Vitro Study ◽  
Electrospun Scaffold ◽  
Single Walled Carbon Nanotube ◽  
Single Walled Carbon ◽  
Amine Functionalized

Three-Dimensionally Printed Polycaprolactone and β-Tricalcium Phosphate Scaffolds for Bone Tissue Engineering: An In Vitro Study

2012 ◽  
Vol 70 (3) ◽  
pp. 647-656 ◽  
Author(s):  
Basel Sharaf ◽  
Caroline B. Faris ◽  
Harutsugi Abukawa ◽  
Srinivas M. Susarla ◽  
Joseph P. Vacanti ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Bone Tissue Engineering ◽  
Bone Tissue ◽  
Tricalcium Phosphate ◽  
In Vitro Study ◽  
Vitro Study

scholarly journals Skeletal Stem Cells—A Paradigm Shift in the Field of Craniofacial Bone Tissue Engineering

2020 ◽  
Vol 1 ◽  
Author(s):  
Ruth Tevlin ◽  
Michael T. Longaker ◽  
Derrick C. Wan
Keyword(s):  
Tissue Engineering ◽  
Stem Cell ◽  
Bone Tissue Engineering ◽  
Bone Tissue ◽  
Systemic Disease ◽  
Direct Result ◽  
Craniofacial Skeleton ◽  
Craniofacial Bone

Defects of the craniofacial skeleton arise as a direct result of trauma, diseases, oncological resection, or congenital anomalies. Current treatment options are limited, highlighting the importance for developing new strategies to restore form, function, and aesthetics of missing or damaged bone in the face and the cranium. For optimal reconstruction, the goal is to replace “like with like.” With the inherent challenges of existing options, there is a clear need to develop alternative strategies to reconstruct the craniofacial skeleton. The success of mesenchymal stem cell-based approaches has been hampered by high heterogeneity of transplanted cell populations with inconsistent preclinical and clinical trial outcomes. Here, we discuss the novel characterization and isolation of mouse skeletal stem cell (SSC) populations and their response to injury, systemic disease, and how their re-activation in vivo can contribute to tissue regeneration. These studies led to the characterization of human SSCs which are able to self-renew, give rise to increasingly fate restricted progenitors, and differentiate into bone, cartilage, and bone marrow stroma, all on the clonal level in vivo without prior in vitro culture. SSCs hold great potential for implementation in craniofacial bone tissue engineering and regenerative medicine. As we begin to better understand the diversity and the nature of skeletal stem and progenitor cells, there is a tangible future whereby a subset of human adult SSCs can be readily purified from bone or activated in situ with broad potential applications in craniofacial tissue engineering.

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