Swelling and Mechanical Properties of Biopolymer Hydrogels Containing Chitosan and Bovine Serum Albumin

2006 ◽  
Vol 7 (11) ◽  
pp. 2961-2970 ◽  
Author(s):  
Michael F. Butler ◽  
Allan H. Clark ◽  
Sarah Adams
Keyword(s):  
Mechanical Properties ◽  
Bovine Serum Albumin ◽  
Serum Albumin ◽  
Bovine Serum

scholarly journals An injectable glass polyalkenoate cement engineered for fracture fixation and stabilization

2021 ◽  
Author(s):  
Basel A. Khader ◽  
Sean A. F. Peel ◽  
Mark R. Towler
Keyword(s):  
Mechanical Properties ◽  
Bovine Serum Albumin ◽  
Serum Albumin ◽  
Fracture Fixation ◽  
Bovine Serum ◽  
Germanium Oxide ◽  
Setting Times ◽  
Ability To Act ◽  
Keywords Fracture ◽  
Glass Polyalkenoate Cement

Glass polyalkenoate cements (GPCs) have potential as bio-adhesives due to their ease of application, appropriate mechanical properties, radiopacity and chemical adhesion to bone. Aluminium (Al)-free GPCs have been discussed in the literature, but have proven difficult to balance injectability with mechanical integrity. For example, zinc-based, Al-free GPCs reported compressive strengths of 63 MPa, but set in under 2 min. Here, the authors design injectable GPCs (IGPCs) based on zinc-containing, Al-free silicate compositions containing GeO2, substituted for ZnO at 3% increments through the series. The setting reactions, injectability and mechanical properties of these GPCs were evaluated using both a hand-mix (h) technique, using a spatula for sample preparation and application and an injection (i) technique, using a 16-gauge needle, post mixing, for application. GPCs ability to act as a carrier for bovine serum albumin (BSA) was also evaluated. Germanium (Ge) and BSA containing IGPCs were produced and reported to have working times between 26 and 44 min and setting times between 37 and 55 min; the extended handling properties being as a result of less Ge. The incorporation of BSA into the cement had no effect on the handling and mechanical properties, but the latter were found to have increased compression strength with the addition of Ge from between 27 and 37 MPa after 30 days maturation. Keywords: fracture fixation; distal radius fracture; germanium oxide; polyacrylic acid; injectable glass polyalkenoate cements; bovine serum albumin

scholarly journals An injectable glass polyalkenoate cement engineered for fracture fixation and stabilization

2021 ◽  
Author(s):  
Basel A. Khader ◽  
Sean A. F. Peel ◽  
Mark R. Towler
Keyword(s):  
Mechanical Properties ◽  
Bovine Serum Albumin ◽  
Serum Albumin ◽  
Fracture Fixation ◽  
Bovine Serum ◽  
Germanium Oxide ◽  
Setting Times ◽  
Ability To Act ◽  
Keywords Fracture ◽  
Glass Polyalkenoate Cement

Glass polyalkenoate cements (GPCs) have potential as bio-adhesives due to their ease of application, appropriate mechanical properties, radiopacity and chemical adhesion to bone. Aluminium (Al)-free GPCs have been discussed in the literature, but have proven difficult to balance injectability with mechanical integrity. For example, zinc-based, Al-free GPCs reported compressive strengths of 63 MPa, but set in under 2 min. Here, the authors design injectable GPCs (IGPCs) based on zinc-containing, Al-free silicate compositions containing GeO2, substituted for ZnO at 3% increments through the series. The setting reactions, injectability and mechanical properties of these GPCs were evaluated using both a hand-mix (h) technique, using a spatula for sample preparation and application and an injection (i) technique, using a 16-gauge needle, post mixing, for application. GPCs ability to act as a carrier for bovine serum albumin (BSA) was also evaluated. Germanium (Ge) and BSA containing IGPCs were produced and reported to have working times between 26 and 44 min and setting times between 37 and 55 min; the extended handling properties being as a result of less Ge. The incorporation of BSA into the cement had no effect on the handling and mechanical properties, but the latter were found to have increased compression strength with the addition of Ge from between 27 and 37 MPa after 30 days maturation. Keywords: fracture fixation; distal radius fracture; germanium oxide; polyacrylic acid; injectable glass polyalkenoate cements; bovine serum albumin

On the mechanical properties of bovine serum albumin (BSA) adhesives

2008 ◽  
Vol 19 (4) ◽  
pp. 1831-1838 ◽  
Author(s):  
N. S. Berchane ◽  
M. J. Andrews ◽  
S. Kerr ◽  
N. K. H. Slater ◽  
F. F. Jebrail
Keyword(s):  
Mechanical Properties ◽  
Bovine Serum Albumin ◽  
Serum Albumin ◽  
Bovine Serum

The Mechanical Properties of Mimic Skin

2020 ◽  
Vol 899 ◽  
pp. 73-80
Author(s):  
Nur Nabila Mohd Nazali ◽  
Nur Ani Aniqah Anirad ◽  
Nor Fazli Adull Manan
Keyword(s):  
Mechanical Properties ◽  
Bovine Serum Albumin ◽  
Serum Albumin ◽  
Bovine Serum ◽  
Numerical Approach ◽  
Skin Layer ◽  
Elastic Behavior ◽  
Uniaxial Tensile ◽  
Uniaxial Tensile Test ◽  
Hyper Elastic

This paper focuses on the characterized of the mechanical properties and hyper elastic behavior of lab made skin. Bovine Serum Albumin (BSA) combined with gelatin as a base. BSA is a plasma lead concentrations or heparin plasma which is separated from blood sample and it is not associated with significant changes in iron or hemoglobin concentrations. In general, the gelatin is widely used as the best material for skin substitution since it exhibits the characteristic of human skin. However, the lab made skin layer was made of non-halal type gelatin (Type B). The methodology process started by adding the BSA and using the type A gelatin to carry out the mechanical properties and hy-per elastic behavior of halal lab made skin layer. A uniaxial tensile test standard that being used in this study is ASTM D412. The raw data (Load-Extension) from computational was plotted on graph stress-strain. The numerical approach such as Mooney-Rivlin model and Yeoh’s model were selected to analyze a stress-stretch of composition gelatin and BSA. From the results Mooney-Rivlin model, the con-stant, C1 is in the range of (0.0187-0.0658) MPa and C2 is in the range of (0.0628-0.0737) MPa. Meanwhile the constant, CP for Yeoh model is in the range of (0.0748-0.0861) MPa. As a conclusion, the composition of gelatin and Bovine Serum Albumin is a best combina-tion as it increases the strength of the lab made skin layer. Therefore, the most suitable composition is 10 wt.% of gelatin and Bovine Serum Albumin.

Improvement of an artificial test substrate technique for evaluation of em immunocytochemical labeling

1987 ◽  
Vol 45 ◽  
pp. 762-763
Author(s):  
G. D. Gagne ◽  
M. F. Miller
Keyword(s):  
Bovine Serum Albumin ◽  
Serum Albumin ◽  
Bovine Serum ◽  
Artificial Substrate ◽  
Chemical Fixation ◽  
As If

We recently described an artificial substrate system which could be used to optimize labeling parameters in EM immunocytochemistry (ICC). The system utilizes blocks of glutaraldehyde polymerized bovine serum albumin (BSA) into which an antigen is incorporated by a soaking procedure. The resulting antigen impregnated blocks can then be fixed and embedded as if they are pieces of tissue and the effects of fixation, embedding and other parameters on the ability of incorporated antigen to be immunocyto-chemically labeled can then be assessed. In developing this system further, we discovered that the BSA substrate can also be dried and then sectioned for immunolabeling with or without prior chemical fixation and without exposing the antigen to embedding reagents. The effects of fixation and embedding protocols can thus be evaluated separately.

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