Physicochemical Characterizations of Self-Assembled Nanoparticles of Glycol Chitosan−Deoxycholic Acid Conjugates

2005 ◽  
Vol 6 (2) ◽  
pp. 1154-1158 ◽  
Author(s):  
Kwangmeyung Kim ◽  
Seunglee Kwon ◽  
Jae Hyung Park ◽  
Hesson Chung ◽  
Seo Young Jeong ◽  
...  
2005 ◽  
Vol 103 (1) ◽  
pp. 235-243 ◽  
Author(s):  
Hyuk Sang Yoo ◽  
Jung Eun Lee ◽  
Hesson Chung ◽  
Ick Chan Kwon ◽  
Seo Young Jeong

Biomaterials ◽  
2012 ◽  
Vol 33 (7) ◽  
pp. 2310-2320 ◽  
Author(s):  
Jing Li ◽  
Meirong Huo ◽  
Jing Wang ◽  
Jianping Zhou ◽  
Jumah M. Mohammad ◽  
...  

2005 ◽  
Vol 109 (25) ◽  
pp. 12270-12276 ◽  
Author(s):  
Pierre Terech ◽  
Neralagatta M. Sangeetha ◽  
Bruno Demé ◽  
Uday Maitra

2010 ◽  
Vol 2010 ◽  
pp. 1-9 ◽  
Author(s):  
Xuemeng Dong ◽  
Chenguang Liu

Novel amphiphilic biopolymers were synthesized using hyaluronic acid (HA) as a hydrophilic segment and deoxycholic acid (DOCA) as a hydrophobic segment by a 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide mediated coupling reaction. The structural characteristics of the HA-DOCA conjugates were investigated usingH1NMR. Self-assembled nanoparticles were prepared based on HA-DOCA conjugates, and its characteristics were investigated using dynamic laser light scattering, transmission electron microscopy (TEM), and fluorescence spectroscopy. The mean diameter was about 293.5 nm with unimodal size distribution in distilled water. The TEM images revealed that the shape of HA-DOCA self-aggregates was spherical. The critical aggregation concentration (CAC) was in the range of 0.025–0.056 mg/mL. The partition equilibrium constant (Kv) of pyrene in self-aggregates solution was from1.45×104to3.64×104. The aggregation number of DOCA groups per hydrophobic microdomain, estimated by the fluorescence quenching method using cetylpyridinium chloride, increased with increasing degree of substitution.


RSC Advances ◽  
2014 ◽  
Vol 4 (98) ◽  
pp. 55139-55149 ◽  
Author(s):  
Jinlong Yang ◽  
Chunmei Gao ◽  
Shaoyu Lü ◽  
Xinggang Wang ◽  
Mingjia Chen ◽  
...  

2004 ◽  
Vol 95 (3) ◽  
pp. 579-588 ◽  
Author(s):  
Jae Hyung Park ◽  
Seunglee Kwon ◽  
Ju-Ock Nam ◽  
Rang-Woon Park ◽  
Hesson Chung ◽  
...  

2014 ◽  
Vol 193 ◽  
pp. 202-213 ◽  
Author(s):  
Ji Young Yhee ◽  
Sohee Son ◽  
Sun Hwa Kim ◽  
Kinam Park ◽  
Kuiwon Choi ◽  
...  

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