Stereocomplex Formation by Enantiomeric Poly(lactic acid) Graft-Type Phospholipid Polymers for Tissue Engineering

2002 ◽  
Vol 3 (5) ◽  
pp. 1109-1114 ◽  
Author(s):  
Junji Watanabe ◽  
Takahisa Eriguchi ◽  
Kazuhiko Ishihara
Keyword(s):  
Tissue Engineering ◽  
Lactic Acid ◽  
Poly Lactic Acid ◽  
Stereocomplex Formation

Development of three-dimensional printing filaments based on poly(lactic acid)/hydroxyapatite composites with potential for tissue engineering

2021 ◽  
pp. 002199832098856
Author(s):  
Marcela Piassi Bernardo ◽  
Bruna Cristina Rodrigues da Silva ◽  
Luiz Henrique Capparelli Mattoso
Keyword(s):  
Tissue Engineering ◽  
Lactic Acid ◽  
Fused Deposition Modeling ◽  
Three Dimensional ◽  
Poly Lactic Acid ◽  
Scanning Calorimetry ◽  
Three Dimensional Printing ◽  
Fused Deposition ◽  
Deposition Modeling ◽  
3D Printed

Injured bone tissues can be healed with scaffolds, which could be manufactured using the fused deposition modeling (FDM) strategy. Poly(lactic acid) (PLA) is one of the most biocompatible polymers suitable for FDM, while hydroxyapatite (HA) could improve the bioactivity of scaffold due to its chemical composition. Therefore, the combination of PLA/HA can create composite filaments adequate for FDM and with high osteoconductive and osteointegration potentials. In this work, we proposed a different approache to improve the potential bioactivity of 3D printed scaffolds for bone tissue engineering by increasing the HA loading (20-30%) in the PLA composite filaments. Two routes were investigated regarding the use of solvents in the filament production. To assess the suitability of the FDM-3D printing process, and the influence of the HA content on the polymer matrix, thermogravimetric analysis (TGA), differential scanning calorimetry (DSC) and scanning electron microscopy (SEM) were performed. The HA phase content of the composite filaments agreed with the initial composite proportions. The wettability of the 3D printed scaffolds was also increased. It was shown a greener route for obtaining composite filaments that generate scaffolds with properties similar to those obtained by the solvent casting, with high HA content and great potential to be used as a bone graft.

3D-poly (lactic acid) scaffolds coated with gelatin and mucic acid for bone tissue engineering

2020 ◽  
Vol 162 ◽  
pp. 523-532 ◽  
Author(s):  
B. Ashwin ◽  
B. Abinaya ◽  
T.P. Prasith ◽  
S. Viji Chandran ◽  
L. Roshini Yadav ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Lactic Acid ◽  
Bone Tissue Engineering ◽  
Bone Tissue ◽  
Poly Lactic Acid ◽  
Mucic Acid

Fabrication of core-shell structured nanofibers of poly (lactic acid) and poly (vinyl alcohol) by coaxial electrospinning for tissue engineering

2018 ◽  
Vol 98 ◽  
pp. 483-491 ◽  
Author(s):  
Hamad F. Alharbi ◽  
Monis Luqman ◽  
Khalil Abdelrazek Khalil ◽  
Yasser A. Elnakady ◽  
Omar H. Abd-Elkader ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Lactic Acid ◽  
Vinyl Alcohol ◽  
Poly Lactic Acid ◽  
Poly Vinyl Alcohol ◽  
Coaxial Electrospinning ◽  
Core Shell
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