Maqui Berry (Aristotelia chilensis) Juices Fermented with Yeasts: Effects on Phenolic Composition, Antioxidant Capacity, and iNOS and COX-2 Protein Expression

Author(s):  
Jin Zhi Wang ◽  
Gad G. Yousef ◽  
Randy B. Rogers ◽  
Elvira Gonzalez de Mejia ◽  
Ilya Raskin ◽  
...  
LWT ◽  
2012 ◽  
Vol 47 (2) ◽  
pp. 279-286 ◽  
Author(s):  
Amadeo Gironés-Vilaplana ◽  
Pedro Mena ◽  
Cristina García-Viguera ◽  
Diego A. Moreno

2016 ◽  
Vol 54 (2) ◽  
Author(s):  
Ana Ljevar ◽  
◽  
Natka Ćurko ◽  
Marina Tomašević ◽  
Kristina Radošević ◽  
...  

1970 ◽  
Vol 7 (3) ◽  
pp. 14-19 ◽  
Author(s):  
Hekdin Marsius Sipayung ◽  
Jansen Silalahi ◽  
Yuandani Y

Objectives: The objective of this study was to investigate the activity of combination of hydrolyzed VCO (HVCO) and chitosan on NIH 3T3 cell proliferation activity, NIH 3T3 cell migration, COX-2 and VEGF protein expression. Design: In vitro cytotoxic assay was determined by MTT (MicrocultureTetrazoliumTehnique) assay, cell proliferation activity was measured by calculating cell viability incubated 24 hours, 48 hours and 72 hours, wound closure percentage was tested by scratch wound healing method, expression of COX-2 protein and VEGF protein were measured by immunocytochemical method. Interventions: The variable that was intervened in this study was the concentration of HVCO and chitosan. Main Outcome Measures: The main measurements carried out in this study were the absorbance value of HVCO and chitosan which was converted into viability cell, proliferation activity, percentage of wound closure, and percentage of COX-2 and VEGF protein expression. Results: Cytotoxic activity of HVCO and chitosan resulted the best concentration at 31.25 μg/ml, scratch wound healing assay from a combination HVCO and chitosan resulted the best migration of fibroblast cells at a ratio of 1:1 with HVCO 62.5 μg/ml and chitosan 62.5 μg/ml, combination of HVCO 62.5 μg/ml and chitosan 62.5 μg/ml (1:1) increased expression of COX-2 and VEGF. Conclusion: Combination of HVCO and chitosan could increase NIH 3T3 cell migration, COX-2 and VEGF protein expression. Combination of HVCO and chitosan had better wound healing activity in vitro than single use. Keywords: Rhizomucor miehei, viability, proliferation, migration, expression


2020 ◽  
pp. 273-283
Author(s):  
Iis Wahyuningsih ◽  
Kurnia Ambarwati ◽  
Erninda Ayu Hapsari ◽  
Afifah Fauziyyah ◽  
Azis Ikhsanudin ◽  
...  

The aim of this study was to determine the protection effect of SNEDDS piroxicam ulcerogenic agent against malondialdehyde (MDA) level and protein expression of caspase-3, COX-1, COX-2. The research was conducted using the test animals as much as 30 male white Sprague dawley (SD) rats aged 1-2 months with a weight of 100-200 grams divided into 5 groups. Treatment was given for 28 days orally. On the 29th day blood samples were also taken for the determination of MDA (Malondialdehid) levels by Thiobarbituric Acid Reactive Substance (TBARs) method using a visible spectrophotometer. Rats were sacrificed, then gastric organs were taken for immunohistochemical testing of caspase-3 and COX-1 expression, COX-2. The statistical analysis showed that the piroxicam SNEDDS group and the piroxicam suspension group decreased expression of the caspase-3 protein, increased COX-1 expression, decreased COX-2 and significantly decreased MDA levels. The piroxicam-containing SNEDDS (Self-Nanoemulsifying Drug Delivery System) form has protection against ulcogenic piroxicam.


2010 ◽  
Vol 120 (4) ◽  
pp. 1201-1209 ◽  
Author(s):  
Şeyda Karaman ◽  
Esma Tütem ◽  
Kevser Sözgen Başkan ◽  
Reşat Apak

LWT ◽  
2018 ◽  
Vol 96 ◽  
pp. 322-328 ◽  
Author(s):  
M. Cano-Lamadrid ◽  
F. Hernández ◽  
P. Nowicka ◽  
A.A. Carbonell-Barrachina ◽  
A. Wojdyło

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