Controlling Dengue Virus Transmission in the Field with Genetically Modified Mosquitoes

2009 ◽  
pp. 123-141 ◽  
Author(s):  
Ken E. Olson ◽  
Alexander W. E. Franz
Keyword(s):  
Dengue Virus ◽  
Genetically Modified ◽  
Virus Transmission ◽  
Genetically Modified Mosquitoes

scholarly journals Dengue Virus Transmission from Donor to Recipient during Haploidentical Stem Cell Transplantation

IDCases ◽  
2021 ◽  
pp. e01220
Author(s):  
Anjali Yadav ◽  
Neha Rastogi ◽  
K. Upasana ◽  
Sunisha Arora ◽  
Dhwanee Thakkar ◽  
...  
Keyword(s):  
Stem Cell ◽  
Stem Cell Transplantation ◽  
Dengue Virus ◽  
Cell Transplantation ◽  
Virus Transmission ◽  
Haploidentical Stem Cell Transplantation

scholarly journals TRANSMISI TRANSOVARIAL VIRUS DENGUE PADA NYAMUKAEDES SPP.

2013 ◽  
Vol 5 (1) ◽  
Author(s):  
Angle M. H. Sorisi
Keyword(s):  
Dengue Virus ◽  
Vertical Transmission ◽  
Dengue Hemorrhagic Fever ◽  
Virus Transmission ◽  
Hemorrhagic Fever ◽  
Health Problems ◽  
Transovarial Transmission ◽  
Blood Sucking ◽  
Endemic Areas ◽  
And Control

Abstract: Dengue Hemorrhagic Fever (DHF) is one of the most serious health problems in Indonesia which often causes outbreaks with numerous deaths. The disease is transmitted byAedes sp.females. Generally, dengue virus transmission occurs horizontally from human carriers, and the dengue viruses are passed on bytheir vectors through blood sucking activity. After propagation in the mosquito, the viruses are transmitted to human recipients. In addition, there is a vertical transmission (transovarial) of dengue virusesin the ova of Aedes sp.females. The viruses propagate in the ova that undergo  metamorphosis to become larvae, pupae, and imagoes. The transovarial transmission of dengue virusesin its vectors in endemic areas could be a causative key which is responsible for the phenomenon of increasing cases of DHF. Any effort to prevent and control DHF requires a thorough understanding about virDen transmission, including this transovarial transmission in Aedes spfemales. Keywords: DHF, transovarial transmission, Aedes sp.     Abstrak: Penyakit Demam Berdarah Dengue (DBD) merupakan salah satu masalah kesehatan yang semakin serius di Indonesia dan sering menimbulkan suatu Kejadian Luar Biasa (KLB) dengan jumlah kematian tinggi. Penyakit ditularkan melalui Aedes sp.betina. Transmisi virus dengue umumnya terjadi secara horizontal, yaitu dari manusia pembawa virus dengue ke nyamuk vektor Aedes sp. melalui aktivitasnya mengisap darahSetelah mengalami propagasi  dalam  tubuh nyamuk, virus dengue ditularkan ke  manusia penerima. Selain itu, transmisi virus dapat terjadi secara vertikal (transovarial) yaitu virus dengue dalam tubuh nyamuk vektorAedes sp. betinake ovum, kemudian berpropagasi dalam ovum, larva, pupa, dan imago. Transmisi transovarial virus dengueke vektornya di daerah endemik bisa menjadi kunci penyebab yang bertanggung jawab terhadap fenomena peningkatan kasus deman berdarah dengue. Upaya pencegahan dan penanggulangan DBD memerlukan pengetahuan yang matang tentang adanya infeksi transovarial virDen pada nyamuk Aedes sp. Kata kunci : DBD, transmisi transovarial,  Aedes sp.

scholarly journals Knowledge About Dengue Fever Prevention Among People Visiting Benazir Bhutto Hospital

2020 ◽  
Vol 24 (1) ◽  
pp. 23-26
Author(s):  
Tamanna Fayyaz ◽  
Maria Yasin ◽  
Ahsan Tariq ◽  
Aashi Mughal ◽  
Mujtaba Haider Bukhari ◽  
...  
Keyword(s):  
Dengue Virus ◽  
Dengue Fever ◽  
Public Awareness ◽  
Virus Transmission ◽  
Cross Sectional Study ◽  
Ethical Review ◽  
Health Campaigns ◽  
Cross Sectional ◽  
High Knowledge ◽  
Public Health Campaigns

Background: The higher incidence of dengue fever in Pakistan demands additional efforts in order to limit the disease. Despite active public health campaigns, low public awareness is one of the factors facilitating dengue virus transmission. For effective preventive measures, the assessment of the knowledge gap and then taking appropriate steps to fill the gap is required.The objective of this study is to assess knowledge about dengue fever prevention among people visiting Benazir Bhutto Hospital, Rawalpindi.Methods: The descriptive cross-sectional study of 6 months duration was conducted with 280 participants selected via nonprobability convenience sampling. After informed consent, an interview was conducted based on a questionnaire that assessed socio-demographic parameters and knowledge about dengue virus transmission and prevention. Data were analyzed through SPSS v. 22. The study was approved by the Ethical Review Board (ERB) of Rawalpindi Medical University and Allied hospitals.Results: Out of 280 respondents, 54.6% were males and 45.4% females and the mean age was 35.0 ± 13.1 years. The respondents having high knowledge scores were 66(23.6%) while those having moderate and low scores were 159 (56.8%) and 55 (19.6%) respectively. Educated respondents (p=0.03) and urban residents (p=0.05) had higher knowledge scores.Conclusion: The majority of the participants know about dengue fever. However, only one out of every four respondents has good knowledge scores for dengue fever prevention.

scholarly journals House-to-house human movement drives dengue virus transmission

2012 ◽  
Vol 110 (3) ◽  
pp. 994-999 ◽  
Author(s):  
S. T. Stoddard ◽  
B. M. Forshey ◽  
A. C. Morrison ◽  
V. A. Paz-Soldan ◽  
G. M. Vazquez-Prokopec ◽  
...  
Keyword(s):  
Dengue Virus ◽  
Virus Transmission ◽  
Human Movement

scholarly journals Dengue Virus Transmission from Living Donor to Recipient in Liver Transplantation: A Case Report

2016 ◽  
Vol 6 (1) ◽  
pp. 59-61 ◽  
Author(s):  
Raman K. Gupta ◽  
Gaurav Gupta ◽  
Vishal K. Chorasiya ◽  
Pradyut Bag ◽  
Rajeev Shandil ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Case Report ◽  
Dengue Virus ◽  
Living Donor ◽  
Virus Transmission

scholarly journals Field- and clinically derived estimates of Wolbachia-mediated blocking of dengue virus transmission potential in Aedes aegypti mosquitoes

2017 ◽  
Vol 115 (2) ◽  
pp. 361-366 ◽  
Author(s):  
Lauren B. Carrington ◽  
Bich Chau Nguyen Tran ◽  
Nhat Thanh Hoang Le ◽  
Tai Thi Hue Luong ◽  
Truong Thanh Nguyen ◽  
...  
Keyword(s):  
Aedes Aegypti ◽  
Dengue Virus ◽  
Virus Transmission ◽  
Field Testing ◽  
Denv Infection ◽  
Ho Chi Minh City ◽  
Wild Type ◽  
Transmission Potential ◽  
Blood Meals ◽  
Increased Susceptibility

The wMel strain of Wolbachia can reduce the permissiveness of Aedes aegypti mosquitoes to disseminated arboviral infections. Here, we report that wMel-infected Ae. aegypti (Ho Chi Minh City background), when directly blood-fed on 141 viremic dengue patients, have lower dengue virus (DENV) transmission potential and have a longer extrinsic incubation period than their wild-type counterparts. The wMel-infected mosquitoes that are field-reared have even greater relative resistance to DENV infection when fed on patient-derived viremic blood meals. This is explained by an increased susceptibility of field-reared wild-type mosquitoes to infection than laboratory-reared counterparts. Collectively, these field- and clinically relevant findings support the continued careful field-testing of wMel introgression for the biocontrol of Ae. aegypti-born arboviruses.

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