The Assembly and Disassembly of Biopolyelectrolyte Multilayers and Their Potential in the Encapsulation and Controlled Release of Active Ingredients from Foods

Author(s):  
J. Moffat ◽  
R. Parker ◽  
T. R. Noel ◽  
D. Duta ◽  
S. G. Ring
2019 ◽  
Vol 17 (1) ◽  
Author(s):  
Marcela Candido Camara ◽  
Estefânia Vangelie Ramos Campos ◽  
Renata Aparecida Monteiro ◽  
Anderson do Espirito Santo Pereira ◽  
Patrícia Luiza de Freitas Proença ◽  
...  

Abstract Pesticides and fertilizers are widely used to enhance agriculture yields, although the fraction of the pesticides applied in the field that reaches the targets is less than 0.1%. Such indiscriminate use of chemical pesticides is disadvantageous due to the cost implications and increasing human health and environmental concerns. In recent years, the utilization of nanotechnology to create novel formulations has shown great potential for diminishing the indiscriminate use of pesticides and providing environmentally safer alternatives. Smart nano-based pesticides are designed to efficiently delivery sufficient amounts of active ingredients in response to biotic and/or abiotic stressors that act as triggers, employing targeted and controlled release mechanisms. This review discusses the current status of stimuli-responsive release systems with potential to be used in agriculture, highlighting the challenges and drawbacks that need to be overcome in order to accelerate the global commercialization of smart nanopesticides.


2014 ◽  
Vol 12 (4) ◽  
pp. 453-469 ◽  
Author(s):  
Anamika Roy ◽  
Sunil Singh ◽  
Jaya Bajpai ◽  
Anil Bajpai

AbstractPolymers have been widely used in agriculture for applications including controlled release of pesticides and other active ingredients. The ability to predict their delivery helps avoid environmental hazards. Macromolecular matrices used as carriers in controlled release of agricultural active agents, especially pesticides, are reviewed. The review focuses on the advantages and mechanisms of controlled release. It includes biodegradable polymers in agriculture, their manufacturing methods, and their degradation mechanisms and kinetics. The article also presents a critical account of recent release studies and considers upcoming challenges.


2019 ◽  
Vol 70 (2) ◽  
pp. 425-430 ◽  
Author(s):  
Alin Laurentiu Tatu ◽  
Alina Mihaela Elisei ◽  
Violeta Bezman ◽  
Camelia Diaconu ◽  
Olimpia Dumitriu Buzia

The present study aims at obtaining an efficient local formulation able to ensure both stability and increased penetration of the active ingredients in effective optimal concentrations without side-effects. The novelty of this study is the association in an encapsulated form (liposomes) of tretinoin to benzoyl peroxide as an innovative alternative capable of minimizing side-effects, but preserving at the same time their efficiency. The pharmaceutical forms using liposomes ensure the controlled release of medicine, as a result of the encapsulation of the active substances in the amphiphile structure�liposomes, with the possibility to diminish irritating secondary reactions in various forms of acne, and to provide efficiency, tollerability, conformity and cosmetic acceptability, to be proved in a future study.


2020 ◽  
Vol 22 (1) ◽  
pp. 182-190
Author(s):  
Hao Ran ◽  
Weibin Liu ◽  
Xin Pan ◽  
Chuanbin Wu ◽  
Guilan Quan ◽  
...  

Background: The administration of many pharmaceutical active ingredients is often performed by the injection of an aqueous-based solution. Numerous active ingredients are however, insoluble in water, which complicates their administration and restricts their efficacy. Objective: The current solutions are hindered by both, a time-consuming manufacturing process and unsuitability for hydrophilic and hydrophobic materials. Method: Emulsions of oleophilic active ingredients and polyprotein microspheres are an important step to overcome insolubility issues. Results: Polyprotein microspheres offer a versatile modifiable morphology, thermal responsivity, and size variation, which allows for the protection and release of assembled biomaterials. In addition, nanospheres present promising cell phagocytosis outcomes in vivo. Conclusion: In this research, a reproducible multifunctional approach, to assemble nanospheres in one step, using a technique termed “automatic nanoscalar interfacial alternation in emulsion” (ANIAE) was developed, incorporating a thermally controlled release mechanism for the assembled target active ingredients. These results demonstrate a viable, universal, multifunctional principal for the pharmaceutical industry.


2009 ◽  
Vol 00 (00) ◽  
pp. 090805050810080-8 ◽  
Author(s):  
Handoko Adi ◽  
Paul Michael Young ◽  
Hak-Kim Chan ◽  
Rania Salama ◽  
Daniela Traini

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