A Novel Peroral Peptide Drug Delivery System Based on Superporous Hydrogel Polymers

2004 ◽  
pp. 296-316
Author(s):  
G. Borchard ◽  
F. A. Dorkoosh ◽  
J. C. Verhoef ◽  
M. Rafiee-Tehrani ◽  
H. E. Junginger
Keyword(s):  
Drug Delivery ◽  
Drug Delivery System ◽  
Delivery System ◽  
Peptide Drug ◽  
Hydrogel Polymers ◽  
Peroral Peptide Drug Delivery ◽  
Superporous Hydrogel

Development and characterization of a novel peroral peptide drug delivery system

2001 ◽  
Vol 71 (3) ◽  
pp. 307-318 ◽  
Author(s):  
Farid A Dorkoosh ◽  
J.C Verhoef ◽  
G Borchard ◽  
M Rafiee-Tehrani ◽  
Hans E Junginger
Keyword(s):  
Drug Delivery ◽  
Drug Delivery System ◽  
Delivery System ◽  
Peptide Drug ◽  
Peroral Peptide Drug Delivery

A biotin-guided fluorescent-peptide drug delivery system for cancer treatment

2014 ◽  
Vol 50 (57) ◽  
pp. 7690 ◽  
Author(s):  
Taeyoung Kim ◽  
Hyun Mi Jeon ◽  
Hoa Thi Le ◽  
Tae Woo Kim ◽  
Chulhun Kang ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Cancer Treatment ◽  
Drug Delivery System ◽  
Delivery System ◽  
Peptide Drug ◽  
Fluorescent Peptide

scholarly journals Development of Bioadhesive Chitosan Superporous Hydrogel Composite Particles Based Intestinal Drug Delivery System

2013 ◽  
Vol 2013 ◽  
pp. 1-10 ◽  
Author(s):  
Hitesh Chavda ◽  
Ishan Modhia ◽  
Anant Mehta ◽  
Rupal Patel ◽  
Chhagan Patel
Keyword(s):  
Drug Delivery ◽  
Drug Release ◽  
Drug Delivery System ◽  
Delivery System ◽  
Drug Transport ◽  
Release Kinetics ◽  
Hydrogel Composite ◽  
Intestinal Delivery ◽  
Superporous Hydrogel

Bioadhesive superporous hydrogel composite (SPHC) particles were developed for an intestinal delivery of metoprolol succinate and characterized for density, porosity, swelling, morphology, and bioadhesion studies. Chitosan and HPMC were used as bioadhesive and release retardant polymers, respectively. A 32full factorial design was applied to optimize the concentration of chitosan and HPMC. The drug loaded bioadhesive SPHC particles were filled in capsule, and the capsule was coated with cellulose acetate phthalate and evaluated for drug content,in vitrodrug release, and stability studies. To ascertain the drug release kinetics, the drug release profiles were fitted for mathematical models. The prepared system remains bioadhesive up to eight hours in intestine and showed Hixson-Crowell release with anomalous nonfickian type of drug transport. The application of SPHC polymer particles as a biomaterial carrier opens a new insight into bioadhesive drug delivery system and could be a future platform for other molecules for intestinal delivery.

Routes and barriers associated with protein and peptide drug delivery system

2021 ◽  
Vol 71 (8) ◽  
pp. 2032-2039
Author(s):  
Saba Saeed ◽  
Mavra Irfan ◽  
Saima Naz ◽  
Momil Liaquat ◽  
Shafaq Jahan ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Drug Delivery System ◽  
Delivery System ◽  
Peptide Drug

Published in August 2021

Multifunctional Tumor-Targeted Polymer-Peptide-Drug Delivery System for Treatment of Primary and Metastatic Cancers

2010 ◽  
Vol 27 (11) ◽  
pp. 2296-2306 ◽  
Author(s):  
Pooja Chandna ◽  
Jayant J. Khandare ◽  
Elizabeth Ber ◽  
Lorna Rodriguez-Rodriguez ◽  
Tamara Minko
Keyword(s):  
Drug Delivery ◽  
Drug Delivery System ◽  
Delivery System ◽  
Peptide Drug
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