Process Research Leading to an Enantioselective Synthesis of a 5-Lipoxygenase Inhibitor for Asthma

2003 ◽  
pp. 141-159
Author(s):  
David B. Damon ◽  
Michael Butters ◽  
Robert W. Dugger ◽  
Peter Dunn ◽  
Sally Gut ◽  
...  
Keyword(s):  
Process Research ◽  
Enantioselective Synthesis ◽  
Lipoxygenase Inhibitor

Catalytic enantioselective synthesis of indolizino[8,7-b]indole alkaloid derivatives based on the tandem reaction of tertiary enamides

2021 ◽  
Author(s):  
Xin-Ming Xu ◽  
Ming Xie ◽  
Jiazhu Li ◽  
Mei-Xiang Wang
Keyword(s):  
Indole Alkaloid ◽  
Enantioselective Synthesis ◽  
High Yield ◽  
Tandem Reaction ◽  
Indole Derivatives

An exquisite Pybox/Cu(OTf)2-catalyzed asymmetric tandem reaction of tertiary enamides was developed, which enabled the expeditious synthesis of indolizino[8,7-b]indole derivatives in high yield, excellent enantioselectivity and diastereoselectivity.

New Life for Process Research

1988 ◽  
Vol 33 (9) ◽  
pp. 802-803
Author(s):  
Edward S. Bordin
Keyword(s):  
Process Research
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