Estimating Chlorinated Ethene Bioattenuation Rates from a Single Well

2002 ◽  
pp. 109-118
Author(s):  
Brian S. Aiken ◽  
Laurie LaPat-Polasko
Keyword(s):  
Chlorinated Ethene ◽  
Single Well

An Effective Approach for Automatic Rock-Typing and Calibration Using Single-Well Models

2011 ◽  
Author(s):  
Sachin Kumar Sharma ◽  
Alexis Vincent Carrillat ◽  
Torsten Friedel
Keyword(s):  
Rock Typing ◽  
Single Well ◽  
Well Models

No Wait-On-Cement (NO WOC) Successfully Applied in Pertamina Hulu Mahakam (PHM) and Creating Significant Well Rig Time Saving

2020 ◽  
Author(s):  
H., A. Sinaga
Keyword(s):  
Hard Work ◽  
Time Saving ◽  
Drilling Technique ◽  
Single Well ◽  
No Wait

As the new operator of the Mahakam Block started in 2017, Pertamina Hulu Mahakam (PHM) were challenged to ramp up operations in order to combat massive production decline. At the same time, reducing well cost was also a paramount importance to ensure that the economic targets of the wells were achieved following the reduction of well stakes. One of the remaining unsolved enigmas is how to achieve No Wait-on-Cement (NO WOC) on surface diverter section as this will create a lot of rig time saving both on single well and batch operations. The project begins with several different kinds of proposal until the best solutions were identified fulfilling safety, simplicity of operations and acceptable cost and finally were put in place with very satisfying results. The main key principle is conversion wellhead stages following well architecture while there were several modifications of casing hanger, adapter, additional materials & modified procedure. Rig time saving, additional operational gain and a promising new “breakthrough” of drilling technique become a significant impact of the successful effort. Now the method has become a standard in PHM operations and has already been integrated to SDI (Standard Drilling Instruction). The merit of this endless hard work could possibly be gained by other operators as it will create more added values both tangible and intangible.

Gas-Water Flow Behaviour During Mutual Displacement in Porous Media

2017 ◽  
Vol 10 (1) ◽  
pp. 13-22
Author(s):  
Renyi Cao ◽  
Junjie Xu ◽  
Xiaoping Yang ◽  
Renkai Jiang ◽  
Changchao Chen
Keyword(s):  
Porous Media ◽  
Relative Permeability ◽  
Gas Storage ◽  
Fluid Distribution ◽  
Water Displacement ◽  
Phase Zone ◽  
Two Phase ◽  
Flow Process ◽  
Single Well ◽  
Mutual Displacement

During oilfield development, there exist multi-cycle gas–water mutual displacement processes. This means that a cycling process such as water driving gas–gas driving water–water driving gas is used for the operation of injection and production in a single well (such as foam huff and puff in single well or water-bearing gas storage). In this paper, by using core- and micro-pore scales model, we study the distribution of gas and water and the flow process of gas-water mutual displacement. We find that gas and water are easier to disperse in the porous media and do not flow in continuous gas and water phases. The Jamin effect of the gas or bubble becomes more severe and makes the flow mechanism of multi-cycle gas–water displacement different from the conventional water driving gas or gas driving water processes. Based on experiments of gas–water mutual displacement, the changing mechanism of gas–water displacement is determined. The results indicate that (1) after gas–water mutual displacement, the residual gas saturation of a gas–water coexistence zone becomes larger and the two-phase zone becomes narrower, (2) increasing the number of injection and production cycles causes the relative permeability of gas to increase and relative permeability for water to decrease, (3) it becomes easier for gas to intrude and the invaded water becomes more difficult to drive out and (4) the microcosmic fluid distribution of each stage have a great difference, which caused the two-phase region becomes narrower and effective volume of gas storage becomes narrower.

scholarly journals SaQuant: a real-time PCR assay for quantitative assessment of Staphylococcus aureus

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Colin Wood ◽  
Jason Sahl ◽  
Sara Maltinsky ◽  
Briana Coyne ◽  
Benjamin Russakoff ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Sensitivity And Specificity ◽  
Pathogen Detection ◽  
Limit Of Detection ◽  
Future Research ◽  
Limit Of Quantification ◽  
Pathogen Prevalence ◽  
Single Well ◽  
Effective Public Health ◽  
Detection And Quantification

Abstract Background Molecular assays are important tools for pathogen detection but need to be periodically re-evaluated with the discovery of additional genetic diversity that may cause assays to exclude target taxa or include non-target taxa. A single well-developed assay can find broad application across research, clinical, and industrial settings. Pathogen prevalence within a population is estimated using such assays and accurate results are critical for formulating effective public health policies and guiding future research. A variety of assays for the detection of Staphylococcus aureus are currently available. The utility of commercial assays for research is limited, given proprietary signatures and lack of transparent validation. Results In silico testing of existing peer-reviewed assays show that most suffer from a lack of sensitivity and specificity. We found no assays that were specifically designed and validated for quantitative use. Here we present a qPCR assay, SaQuant, for the detection and quantification of S. aureus as might be collected on sampling swabs. Sensitivity and specificity of the assay was 95.6 and 99.9 %, respectively, with a limit of detection of between 3 and 5 genome equivalents and a limit of quantification of 8.27 genome equivalents. The presence of DNA from non-target species likely to be found in a swab sample, did not impact qualitative or quantitative abilities of the assay. Conclusions This assay has the potential to serve as a valuable tool for the accurate detection and quantification of S. aureus collected from human body sites in order to better understand the dynamics of prevalence and transmission in community settings.

waveRAPID—A Robust Assay for High-Throughput Kinetic Screens with the Creoptix WAVEsystem

2021 ◽  
pp. 247255522110138
Author(s):  
Önder Kartal ◽  
Fabio Andres ◽  
May Poh Lai ◽  
Rony Nehme ◽  
Kaspar Cottier
Keyword(s):  
Drug Discovery ◽  
Fold Increase ◽  
Microtiter Plate ◽  
Experimental Conditions ◽  
Short Pulses ◽  
Cycle Times ◽  
Fragment Screening ◽  
New Instrument ◽  
Single Well ◽  
Compound Screening

Surface-based biophysical methods for measuring binding kinetics of molecular interactions, such as surface plasmon resonance (SPR) or grating-coupled interferometry (GCI), are now well established and widely used in drug discovery. Increasing throughput is an often-cited need in the drug discovery process and this has been achieved with new instrument generations where multiple interactions are measured in parallel, shortening the total measurement times and enabling new application areas within the field. Here, we present the development of a novel technology called waveRAPID for a further—up to 10-fold—increase in throughput, consisting of an injection method using a single sample. Instead of sequentially injecting increasing analyte concentrations for constant durations, the analyte is injected at a single concentration in short pulses of increasing durations. A major advantage of the new method is its ability to determine kinetics from a single well of a microtiter plate, making it uniquely suitable for kinetic screening. We present the fundamentals of this approach using a small-molecule model system for experimental validation and comparing kinetic parameters to traditional methods. By varying experimental conditions, we furthermore assess the robustness of this new technique. Finally, we discuss its potential for improving hit quality and shortening cycle times in the areas of fragment screening, low-molecular-weight compound screening, and hit-to-lead optimization.

scholarly journals Performance of Hybrid Single Well Enhanced Geothermal System and Solar Energy for Buildings Heating

Energies ◽  
2020 ◽  
Vol 13 (10) ◽  
pp. 2473
Author(s):  
Yujiang He ◽  
Xianbiao Bu
Keyword(s):  
Solar Energy ◽  
Service Life ◽  
Heating System ◽  
Hydrothermal Systems ◽  
Geothermal System ◽  
Heat Output ◽  
Enhanced Geothermal System ◽  
Geothermal Heat ◽  
Hybrid Heating ◽  
Single Well

The energy reserves in hot dry rock and hydrothermal systems are abundant in China, however, the developed resources are far below the potential estimates due to immature technology of enhanced geothermal system (EGS) and scattered resources of hydrothermal systems. To circumvent these problems and reduce the thermal resistance of rocks, here a shallow depth enhanced geothermal system (SDEGS) is proposed, which can be implemented by fracturing the hydrothermal system. We find that, the service life for SDEGS is 14 years with heat output of 4521.1 kW. To extend service life, the hybrid SDEGS and solar energy heating system is proposed with 10,000 m2 solar collectors installed to store heat into geothermal reservoir. The service life of the hybrid heating system is 35 years with geothermal heat output of 4653.78 kW. The novelty of the present work is that the hybrid heating system can solve the unstable and discontinuous problems of solar energy without building additional back-up sources or seasonal storage equipment, and the geothermal thermal output can be adjusted easily to meet the demand of building thermal loads varying with outside temperature.

scholarly journals Methodology for the synthesis of methacrylate monomers using designed single mode microwave applicators

2019 ◽  
Vol 4 (8) ◽  
pp. 1472-1476 ◽  
Author(s):  
Adam A. Dundas ◽  
Andrew L. Hook ◽  
Morgan R. Alexander ◽  
Samuel W. Kingman ◽  
Georgios Dimitrakis ◽  
...  
Keyword(s):  
High Throughput ◽  
Single Mode ◽  
Microwave Reactor ◽  
Reactor Geometry ◽  
Single Well ◽  
Methacrylate Monomers ◽  
Microwave Applicators

A novel single-well prototype high throughput microwave reactor geometry has been produced and shown to be capable of synthesizing an array of non-commercially available methacrylate monomers.

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