Hawthorn (Crataegus): Biological Activity and New Strategies for Quality Control

1998 ◽  
pp. 241-262 ◽  
Author(s):  
O. Sticher ◽  
B. Meier
Keyword(s):  
Quality Control ◽  
Biological Activity ◽  
New Strategies

scholarly journals Quality-control method for the determination of biological activity of engineered calcineurin subunit B

2016 ◽  
Vol 59 (6) ◽  
pp. 584-588
Author(s):  
Xinchang Shi ◽  
Huan Yang ◽  
Li Xu ◽  
Xiang Li ◽  
Zongwen Huang ◽  
...  
Keyword(s):  
Quality Control ◽  
Biological Activity ◽  
Control Method ◽  
Quality Control Method ◽  
Subunit B

Research progress on chemical composition, biological activity, and quality control of Radix Platycodi

2014 ◽  
Vol 6 (6) ◽  
pp. 726
Author(s):  
Ye Yunyun ◽  
Han Lu ◽  
Zhang Yan ◽  
Sun Jiayou ◽  
Zhou Li ◽  
...  
Keyword(s):  
Quality Control ◽  
Biological Activity ◽  
Chemical Composition ◽  
Research Progress

scholarly journals Quantitative In Vitro Bioassay for Recombinant Human Interleukin-11

2000 ◽  
Vol 83 (5) ◽  
pp. 1053-1058 ◽  
Author(s):  
Hiroyuki Yokota ◽  
Mika Kishimoto ◽  
Hiroshi Saito ◽  
Tomoyuki Sakai ◽  
Shoji Yokota ◽  
...  
Keyword(s):  
Cell Culture ◽  
Quality Control ◽  
Biological Activity ◽  
Coefficient Of Variation ◽  
In Vitro Bioassay ◽  
A Cell ◽  
Interleukin 11

Abstract A cell culture-based in vitro bioassay was developed to measure the biological activity of recombinant human interleukin-11 (rhIL-11). The bioassay measures induced proliferation of T10 cells, derived from the T1165 murine plasmacytoma line. A colorimetrically detectable formazan product, obtained by cellular reduction of the tetrazolium compound, 4-[3-(4-iodophenyl)-2-(4-nitrophenyl)-2H-5-tetrazolio]-1, 3-benzene disulfonate (WST-1), was used as an endpoint for response of clone T10 to added rhIL-11. Positions of the samples and the standards in 96-well microplates affected the precision of this bioassay, which was improved by using 2 microplates where serially diluted sample and standard lines were interleaved and their positions were alternated. The coefficient of variation for this bioassay was less than 8%. This method is suitable for quality control of rhIL-11 because of its simplicity, reproducibility, and accuracy.

Quality markers based on biological activity: A new strategy for the quality control of traditional Chinese medicine

Phytomedicine ◽  
2018 ◽  
Vol 44 ◽  
pp. 103-108 ◽  
Author(s):  
Xin Wu ◽  
Hongbing Zhang ◽  
Shanshan Fan ◽  
Yidan Zhang ◽  
Zhen Yang ◽  
...  
Keyword(s):  
Quality Control ◽  
Biological Activity ◽  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
New Strategy ◽  
Quality Markers

scholarly journals Fingerprint Analysis of Cnidium monnieri (L.) Cusson by High-Speed Counter-Current Chromatography

Molecules ◽  
2019 ◽  
Vol 24 (24) ◽  
pp. 4496 ◽  
Author(s):  
Xiaoxue Wu ◽  
Xuemin Gao ◽  
Xuan Zhu ◽  
Shuyi Zhang ◽  
Xinmei Liu ◽  
...  
Keyword(s):  
Quality Control ◽  
Biological Activity ◽  
High Speed ◽  
Solvent System ◽  
Fingerprint Analysis ◽  
Two Phase ◽  
High Biological Activity ◽  
Coumarin Compounds ◽  
Counter Current

Cnidium monnieri (L.) Cusson is a popular Traditional Chinese Medicine (TCM) with a variety of bioactivities. However, there are some problems that have affected the development of Cnidium monnieri (L.) Cusson. At present, many methods have been reported for the analysis of coumarins in Cnidium monnieri (L.) Cusson. However, the quality control of coumarins in Cnidium monnieri (L.) Cusson by high-speed counter-current chromatography (HSCCC) has not been reported. In this study, analytical high-speed counter-current chromatography (HSCCC) was successfully used for fingerprint of Cnidium monnieri (L.) Cusson with a two-phase solvent system composed of n-hexane-ethyl acetate-methanol-water at 4:6:6.5:3.5 (v/v). The UV wavelength was set at 254 nm. Six coumarin compounds with high biological activity were selected as indicator compounds for the quality control. The HSCCC fingerprint of the Cnidium monnieri (L.) Cusson was successfully established and there were some differences according to the results of the fingerprint analysis. The present results demonstrate that HSCCC is an established and efficient technique for the fingerprint analysis of Cnidium monnieri (L.) Cusson and can be used to control the quality of Cnidium monnieri (L.) Cusson. In brief, HSCCC is a useful technology for the fingerprint analytical method for TCM.

scholarly journals Antiviral Potential of Plants against Noroviruses

Molecules ◽  
2021 ◽  
Vol 26 (15) ◽  
pp. 4669
Author(s):  
Jolanta Sarowska ◽  
Dorota Wojnicz ◽  
Agnieszka Jama-Kmiecik ◽  
Magdalena Frej-Mądrzak ◽  
Irena Choroszy-Król
Keyword(s):  
Antimicrobial Activity ◽  
Biological Activity ◽  
Health Costs ◽  
Chemical Compositions ◽  
Plant Metabolites ◽  
Synthetic Chemicals ◽  
Fresh Food ◽  
Food Borne ◽  
Etiological Agents ◽  
New Strategies

Human noroviruses, which belong to the enterovirus family, are one of the most common etiological agents of food-borne diseases. In recent years, intensive research has been carried out regarding the antiviral activity of plant metabolites that could be used for the preservation of fresh food, because they are safer for consumption when compared to synthetic chemicals. Plant preparations with proven antimicrobial activity differ in their chemical compositions, which significantly affects their biological activity. Our review aimed to present the results of research related to the characteristics, applicability, and mechanisms of the action of various plant-based preparations and metabolites against norovirus. New strategies to combat intestinal viruses are necessary, not only to ensure food safety and reduce infections in humans but also to lower the direct health costs associated with them.

Virus-Like Particles in a Human Breast Cancer: Structural Similarity to Previously Reported Particles

1973 ◽  
Vol 31 ◽  
pp. 378-379
Author(s):  
G. Kasnic ◽  
S. E. Stewart ◽  
C. Urbanski
Keyword(s):  
Breast Cancer ◽  
Biological Activity ◽  
Human Breast Cancer ◽  
Osteogenic Sarcoma ◽  
Human Tumor ◽  
Structural Similarity ◽  
Cell Tumor ◽  
Human Breast ◽  
Human Tumor Cell ◽  
Type Particle

We have reported the maturation of an intracisternal A-type particle in murine plasma cell tumor cultures and three human tumor cell cultures (rhabdomyosarcoma, lung adenocarcinoma, and osteogenic sarcoma) after IUDR-DMSO activation. In all of these studies the A-type particle seems to develop into a form with an electron dense nucleoid, presumably mature, which is also intracisternal. A similar intracisternal A-type particle has been described in leukemic guinea pigs. Although no biological activity has yet been demonstrated for these particles, on morphologic grounds, and by the manner in which they develop within the cell, they may represent members of the same family of viruses.

Effects of Vincristine on Endothelial Microtubules in the Spinal Cord

1976 ◽  
Vol 34 ◽  
pp. 58-59
Author(s):  
John L. Beggs ◽  
John D. Waggener ◽  
Wanda Miller
Keyword(s):  
Spinal Cord ◽  
Biological Activity ◽  
Horseradish Peroxidase ◽  
Transport Mechanism ◽  
Vasogenic Edema ◽  
Vesicular Transport ◽  
Close Proximity

Microtubules (MT) are versatile organelles participating in a wide variety of biological activity. MT involvement in the movement and transport of cytoplasmic components has been well documented. In the course of our study on trauma-induced vasogenic edema in the spinal cord we have concluded that endothelial vesicles contribute to the edema process. Using horseradish peroxidase as a vascular tracer, labeled endothelial vesicles were present in all situations expected if a vesicular transport mechanism was in operation. Frequently,labeled vesicles coalesced to form channels that appeared to traverse the endothelium. The presence of MT in close proximity to labeled vesicles sugg ested that MT may play a role in vesicular activity.

CDC Pushing New Strategies for Flu Vaccination

2006 ◽  
Vol 40 (11) ◽  
pp. 12
Author(s):  
HEIDI SPLETE
Keyword(s):  
Flu Vaccination ◽  
New Strategies
Sign in / Sign up

Export Citation Format

Share Document