Search for New Plant Constituents with Antiasthmatic and Antihypertonic Activity

1998 ◽  
pp. 46-61 ◽  
Author(s):  
H. Wagner
Keyword(s):  
Plant Constituents

scholarly journals Sublimation for Enrichment and Identification of Marker Compounds in Fruits

2021 ◽  
Author(s):  
Manuel Gronbach ◽  
Laura Kraußer ◽  
Timo Broese ◽  
Christina Oppermann ◽  
Udo Kragl
Keyword(s):  
Sea Buckthorn ◽  
Food Chemistry ◽  
Food Fraud ◽  
The Past ◽  
Marker Substances ◽  
Plant Powders ◽  
Plant Constituents ◽  
Marker Compounds ◽  
Fruit Powder ◽  
Berry Extracts

AbstractIn this article, we describe the benefits of sublimation for natural product and food chemistry. The direct sublimation of substances from dried plant powders has not received much attention in research in the past, just like the sublimation of substances from dried plant extracts. We used sublimation to study dried sea buckthorn berry powders and dried sea buckthorn berry extracts. The results of the powder sublimations were compared to that of dried chokeberry, wolfberry, and European cornel powder. 52 marker substances of which 27 are specific for sea buckthorn were found in the sea buckthorn powder sublimates using LC/MS. The majority of them are not described in the literature and were obtained by direct sublimation. Accordingly, sublimation can help to identify new plant constituents. Our identification method was validated by the analysis of four commercially available fruit powders. The sea buckthorn powder showed an almost 80% correlation with the determined marker substances, whereas the other fruit powders did not achieve more than 38% correlation. The sublimates of sea buckthorn extracts show additional marker substances compared to the fruit powder sublimate, and we think that both techniques can be used to fight food fraud.

scholarly journals Camphor and Eucalyptol—Anticandidal Spectrum, Antivirulence Effect, Efflux Pumps Interference and Cytotoxicity

2021 ◽  
Vol 22 (2) ◽  
pp. 483
Author(s):  
Marija Ivanov ◽  
Abhilash Kannan ◽  
Dejan S. Stojković ◽  
Jasmina Glamočlija ◽  
Ricardo C. Calhelha ◽  
...  
Keyword(s):  
Fungal Pathogens ◽  
Efflux Pump ◽  
Efflux Pumps ◽  
Liver Cells ◽  
Ergosterol Biosynthesis ◽  
Antifungal Compound ◽  
Porcine Liver ◽  
Fungal Virulence ◽  
Genes Encoding ◽  
Plant Constituents

Candidaalbicans represents one of the most common fungal pathogens. Due to its increasing incidence and the poor efficacy of available antifungals, finding novel antifungal molecules is of great importance. Camphor and eucalyptol are bioactive terpenoid plant constituents and their antifungal properties have been explored previously. In this study, we examined their ability to inhibit the growth of different Candida species in suspension and biofilm, to block hyphal transition along with their impact on genes encoding for efflux pumps (CDR1 and CDR2), ergosterol biosynthesis (ERG11), and cytotoxicity to primary liver cells. Camphor showed excellent antifungal activity with a minimal inhibitory concentration of 0.125–0.35 mg/mL while eucalyptol was active in the range of 2–23 mg/mL. The results showed camphor’s potential to reduce fungal virulence traits, that is, biofilm establishment and hyphae formation. On the other hand, camphor and eucalyptol treatments upregulated CDR1;CDR2 was positively regulated after eucalyptol application while camphor downregulated it. Neither had an impact on ERG11 expression. The beneficial antifungal activities of camphor were achieved with an amount that was non-toxic to porcine liver cells, making it a promising antifungal compound for future development. The antifungal concentration of eucalyptol caused cytotoxic effects and increased expression of efflux pump genes, which suggests that it is an unsuitable antifungal candidate.

Report on Inorganic Plant Constituents

1920 ◽  
Vol 3 (3) ◽  
pp. 329-331
Author(s):  
Andrew J Patten
Keyword(s):  
Plant Constituents

Assessment of Calendula officinal growing in Iraq

2021 ◽  
pp. 5187-5189
Author(s):  
Noor Ali ◽  
Widad M K Al-Ani ◽  
Ibrahim S. Al-Jobouri
Keyword(s):  
Side Effects ◽  
Medicinal Plants ◽  
Medicinal Plant ◽  
Prior Knowledge ◽  
Research Evaluation ◽  
Chemical Constituents ◽  
Plant Constituents ◽  
Time Of Collection

Evaluation of Iraqi medicinal plants is very crucial to help people avoid the use of herbs without prior knowledge which results in many side effects and sometimes even leads to death. The plant constituents vary according to season, weather and type of soil, therefore it is necessary to evaluate the chemical constituents and determine the time of collection of medicinal plants. In this research evaluation of the medicinal plant Calendula officinal grown in Iraq was performed by measuring the quantity of hyperoside found in the plant together with macroscopical and microscopical evaluation of the plant.

Plant Constituents Interfering with Human Sex Hormone-Binding Globulin. Evaluation of a Test Method and Its Application to Urtica dioica Root Extracts

1995 ◽  
Vol 50 (1-2) ◽  
pp. 98-104 ◽  
Author(s):  
Dietmar Ganßer ◽  
Gerhard Spiteller
Keyword(s):  
Test System ◽  
Binding Activity ◽  
Urtica Dioica ◽  
Sex Hormone ◽  
Test Method ◽  
Sex Hormone Binding Globulin ◽  
Hormone Binding ◽  
Root Extracts ◽  
Plant Constituents ◽  
Octadecenoic Acids

Abstract A test system is described, which allows the search for compounds interfering with human sex hormone-binding globulin (SHBG) even in complex plant extracts. The method has been evaluated and applied to Urtica dioica root extracts. The lignan secoisolariciresinol (5) as well as a mixture of isomeric (11 E)-9,10,13-trihydroxy-11-octadecenoic and (10 E)-9 ,12,13-trihydroxy-10-octadecenoic acids (3 and 4, resp.) were demonstrated to reduce binding activity of human SHBG. Methylation of the mixture of 3 and 4 increased its activity about 10-fold.

scholarly journals NUTRITIVE VALUE OF FRESH AND DRIED MARROW-STEM KALE HARVESTED AT TWO DIFFERENT PERIODS

1973 ◽  
Vol 53 (2) ◽  
pp. 257-263 ◽  
Author(s):  
G. PELLETIER ◽  
E. DONEFER
Keyword(s):  
Brassica Oleracea ◽  
Dry Matter ◽  
Nutritive Value ◽  
Chemical Analyses ◽  
High Quality ◽  
Dry Matter Digestibility ◽  
Gross Energy ◽  
Plant Constituents ◽  
Ad Libitum ◽  
Voluntary Intake

Three yearling Cheviot × Suffolk ewes and three Columbia wethers were confined in metabolic cages and fed ad libitum fresh and dried marrow-stem kale (Brassica oleracea var. acephala D.C.) harvested in mid- and late October. Chemical analyses of the forages indicated no marked effects on any of the plant constituents due to drying or advancing maturity. Digestibility measurements demonstrated that marrow-stem kale (MSK) was a highly digestible material with an average dry matter digestibility of 78%. The fresh forages had higher (P < 0.05) dry matter and gross energy digestibility values than the dried form. Dry matter digestibility coefficients were higher (P < 0.05) for late October as compared with the earlier harvest. A trend toward higher (P > 0.05) voluntary intake values due to drying maturity was observed with an average relative intake of 80%. The nutritive value index averaged 65, thus indicating a digestible energy intake similar to a high-quality (legume) forage.

Bioregulation of Plant Constituents

1984 ◽  
pp. 231-250 ◽  
Author(s):  
H. Yokoyama ◽  
W. H. Hsu ◽  
E. Hayman ◽  
S. Poling
Keyword(s):  
Plant Constituents
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