α-Secondary Tritium Kinetic Isotope Effects Indicate Hydrogen Tunneling and Coupled Motion Occur in the Oxidation ofl-Malate by NAD-Malic Enzyme†

William E. Karsten; Chi-Ching Hwang; Paul F. Cook

doi:10.1021/bi982439y

α-Secondary Tritium Kinetic Isotope Effects Indicate Hydrogen Tunneling and Coupled Motion Occur in the Oxidation ofl-Malate by NAD-Malic Enzyme†

Biochemistry ◽

10.1021/bi982439y ◽

1999 ◽

Vol 38 (14) ◽

pp. 4398-4402 ◽

Cited By ~ 17

Author(s):

William E. Karsten ◽

Chi-Ching Hwang ◽

Paul F. Cook

Keyword(s):

Malic Enzyme ◽

Isotope Effects ◽

Kinetic Isotope Effects ◽

Hydrogen Tunneling ◽

Coupled Motion ◽

Kinetic Isotope

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Kinetic Isotope Effects as Probes for Hydrogen Tunneling, Coupled Motion and Dynamics Contributions to Enzyme Catalysis

Progress in Reaction Kinetics and Mechanism ◽

10.3184/007967403103165486 ◽

2003 ◽

Vol 28 (2) ◽

pp. 119-156 ◽

Cited By ~ 57

Author(s):

Amnon Kohen

Keyword(s):

Enzyme Catalysis ◽

Isotope Effects ◽

Kinetic Isotope Effects ◽

Hydrogen Tunneling ◽

Coupled Motion ◽

Kinetic Isotope

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Hydrogen Tunneling in Adenosylcobalamin-Dependent Glutamate Mutase: Evidence from Intrinsic Kinetic Isotope Effects Measured by Intramolecular Competition

Biochemistry ◽

10.1021/bi1001695 ◽

2010 ◽

Vol 49 (14) ◽

pp. 3168-3173 ◽

Cited By ~ 14

Author(s):

Miri Yoon ◽

Hangtian Song ◽

Kristina Håkansson ◽

E. Neil G. Marsh

Keyword(s):

Isotope Effects ◽

Kinetic Isotope Effects ◽

Hydrogen Tunneling ◽

Glutamate Mutase ◽

Kinetic Isotope ◽

Intrinsic Kinetic

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Solution and Computational Studies of Kinetic Isotope Effects in Flavoprotein and Quinoprotein Catalyzed Substrate Oxidations as Probes of Enzymic Hydrogen Tunneling and Mechanism

Isotope Effects In Chemistry and Biology ◽

10.1201/9781420028027.ch25 ◽

2005 ◽

pp. 671-690

Author(s):

Jaswir Basran ◽

Nigel Scrutton ◽

Laura Masgrau ◽

Michael Sutcliffe

Keyword(s):

Isotope Effects ◽

Kinetic Isotope Effects ◽

Computational Studies ◽

Hydrogen Tunneling ◽

Kinetic Isotope

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Kinetic Isotope Effects as Probes for Hydrogen Tunneling in Enzyme Catalysis

Isotope Effects In Chemistry and Biology ◽

10.1201/9781420028027.ch28 ◽

2005 ◽

pp. 743-764 ◽

Cited By ~ 9

Author(s):

Amnon Kohen

Keyword(s):

Enzyme Catalysis ◽

Isotope Effects ◽

Kinetic Isotope Effects ◽

Hydrogen Tunneling ◽

Kinetic Isotope

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The benzidine and diphenyline rearrangements revisited. 1-14C and 1,1'-13C2 kinetic isotope effects, transition state differences, and coupled motion in a 10-atom sigmatropic rearrangement

Journal of the American Chemical Society ◽

10.1021/ja00065a018 ◽

1993 ◽

Vol 115 (12) ◽

pp. 5073-5076 ◽

Cited By ~ 14

Author(s):

Witold Subotkowski ◽

Lidia Kupczyk-Subotkowska ◽

Henry J. Shine

Keyword(s):

Transition State ◽

Isotope Effects ◽

Kinetic Isotope Effects ◽

Sigmatropic Rearrangement ◽

Coupled Motion ◽

Kinetic Isotope

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ChemInform Abstract: The Benzidine and Diphenyline Rearrangements Revisited. 1-14C and 1,1′- 13C2 Kinetic Isotope Effects, Transition State Differences, and Coupled Motion in a 10-Atom Sigmatropic Rearrrangement

ChemInform ◽

10.1002/chin.199342073 ◽

2010 ◽

Vol 24 (42) ◽

pp. no-no

Author(s):

W. SUBOTKOWSKI ◽

L. KUPCZYK-SUBOTKOWSKA ◽

H. J. SHINE

Keyword(s):

Transition State ◽

Isotope Effects ◽

Kinetic Isotope Effects ◽

Coupled Motion ◽

Kinetic Isotope

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Secondary Kinetic Isotope Effects as Probes of Environmentally-Coupled Enzymatic Hydrogen Tunneling Reactions

ChemPhysChem ◽

10.1002/cphc.200800291 ◽

2008 ◽

Vol 9 (11) ◽

pp. 1536-1539 ◽

Cited By ~ 13

Author(s):

Sam Hay ◽

Jiayun Pang ◽

Phillip J. Monaghan ◽

Xi Wang ◽

Rhiannon M. Evans ◽

...

Keyword(s):

Isotope Effects ◽

Kinetic Isotope Effects ◽

Hydrogen Tunneling ◽

Kinetic Isotope

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Sizeable Increase of Kinetic Isotope Effects and Tunnelling in Coupled Electron–Proton Transfers in Presence of the Quaternary Ions. PCET Processes and Hydrogen Tunnelling as a “Probe” for Structuring and Dynamical Phenomena in Water Solution

Zeitschrift für Physikalische Chemie ◽

10.1524/zpch.2012.0150 ◽

2011 ◽

pp. 110923034559006

Author(s):

Cvijeta Jakobušić Brala ◽

Ana Karković ◽

Ivana Sajenko ◽

Viktor Pilepić ◽

Stanko Uršić

Keyword(s):

Water Solution ◽

Isotope Effects ◽

Kinetic Isotope Effects ◽

Kinetic Isotope ◽

Proton Transfers ◽

Sizeable Increase

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Primary and secondary kinetic isotope effects in proton (H+/D+) and chloronium ion (35Cl+/37Cl+) affinities

Journal of Mass Spectrometry ◽

10.1002/jms.219 ◽

2001 ◽

Vol 36 (10) ◽

pp. 1140-1148 ◽

Cited By ~ 20

Author(s):

F�bio Cesar Gozzo ◽

Marcos N. Eberlin

Keyword(s):

Isotope Effects ◽

Kinetic Isotope Effects ◽

Kinetic Isotope

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Theoretical Simulations of Heavy-Atom Kinetic Isotope Effects in Aliphatic Claisen Rearrangement

The Journal of Physical Chemistry A ◽

10.1021/acs.jpca.0c07784 ◽

2020 ◽

Vol 124 (51) ◽

pp. 10678-10686

Author(s):

Yuqing Xu ◽

Kin-Yiu Wong ◽

Meishan Wang ◽

Desheng Liu ◽

Wenkai Zhao ◽

...

Keyword(s):

Claisen Rearrangement ◽

Isotope Effects ◽

Heavy Atom ◽

Kinetic Isotope Effects ◽

Kinetic Isotope ◽

Theoretical Simulations

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