Mapping Substrate-Induced Conformational Changes in cAMP-Dependent Protein Kinase by Protein Footprinting†

Xiaodong Cheng; Shmuel Shaltiel; Susan S. Taylor

doi:10.1021/bi981057p

Mapping Substrate-Induced Conformational Changes in cAMP-Dependent Protein Kinase by Protein Footprinting†

Biochemistry ◽

10.1021/bi981057p ◽

1998 ◽

Vol 37 (40) ◽

pp. 14005-14013 ◽

Cited By ~ 23

Author(s):

Xiaodong Cheng ◽

Shmuel Shaltiel ◽

Susan S. Taylor

Keyword(s):

Protein Kinase ◽

Conformational Changes ◽

Dependent Protein Kinase ◽

Protein Footprinting ◽

Camp Dependent Protein Kinase ◽

Dependent Protein

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Differential labeling of the catalytic subunit of cAMP-dependent protein kinase with acetic anhydride: substrate-induced conformational changes

Biochemistry ◽

10.1021/bi00433a042 ◽

1989 ◽

Vol 28 (7) ◽

pp. 3018-3024 ◽

Cited By ~ 31

Author(s):

Joseph A. Buechler ◽

Thomas A. Vedvick ◽

Susan S. Taylor

Keyword(s):

Protein Kinase ◽

Acetic Anhydride ◽

Conformational Changes ◽

Catalytic Subunit ◽

Dependent Protein Kinase ◽

Camp Dependent Protein Kinase ◽

Dependent Protein

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Distinct conformational changes in the catalytic subunit of cAMP-dependent protein kinase around physiological conditions. Do these changes reflect an ability to assume different specificities?

Biochemical and Biophysical Research Communications ◽

10.1016/0006-291x(80)91183-3 ◽

1980 ◽

Vol 96 (1) ◽

pp. 77-84 ◽

Cited By ~ 16

Author(s):

Abraham Kupfer ◽

Juan S. Jiménez ◽

S. Shaltiel

Keyword(s):

Protein Kinase ◽

Conformational Changes ◽

Catalytic Subunit ◽

Dependent Protein Kinase ◽

Physiological Conditions ◽

Camp Dependent Protein Kinase ◽

Dependent Protein

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Conformational changes of type II regulatory subunit of cAMP- dependent protein kinase on cAMP binding

FEBS Letters ◽

10.1016/0014-5793(89)81395-x ◽

1989 ◽

Vol 247 (2) ◽

pp. 480-482 ◽

Cited By ~ 3

Author(s):

Dennis R. Johnson ◽

Shan S. Wong

Keyword(s):

Protein Kinase ◽

Conformational Changes ◽

Regulatory Subunit ◽

Type Ii ◽

Dependent Protein Kinase ◽

Camp Dependent Protein Kinase ◽

Dependent Protein

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Probing cAMP-Dependent Protein Kinase Holoenzyme Complexes Iα and IIβ by FT-IR and Chemical Protein Footprinting†

Biochemistry ◽

10.1021/bi0354435 ◽

2004 ◽

Vol 43 (7) ◽

pp. 1908-1920 ◽

Cited By ~ 12

Author(s):

Shaoning Yu ◽

Fang C. Mei ◽

J. Ching Lee ◽

Xiaodong Cheng

Keyword(s):

Protein Kinase ◽

Dependent Protein Kinase ◽

Protein Footprinting ◽

Camp Dependent Protein Kinase ◽

Dependent Protein ◽

Ft Ir

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Fluorescence resonance energy transfer within a heterochromatic cAMP-dependent protein kinase holoenzyme under equilibrium conditions: New insights into the conformational changes that result in cAMP-dependent activation

Biochemistry ◽

10.1021/bi00076a013 ◽

1993 ◽

Vol 32 (25) ◽

pp. 6402-6410 ◽

Cited By ~ 34

Author(s):

David A. Johnson ◽

Valerie L. Leathers ◽

Anna M. Martinez ◽

Donal A. Walsh ◽

William H. Fletcher

Keyword(s):

Energy Transfer ◽

Protein Kinase ◽

Fluorescence Resonance Energy Transfer ◽

Conformational Changes ◽

Resonance Energy Transfer ◽

Resonance Energy ◽

Dependent Protein Kinase ◽

Equilibrium Conditions ◽

Camp Dependent Protein Kinase ◽

Dependent Protein

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Staurosporine-induced conformational changes of cAMP-dependent protein kinase catalytic subunit explain inhibitory potential

Structure ◽

10.1016/s0969-2126(97)00310-9 ◽

1997 ◽

Vol 5 (12) ◽

pp. 1627-1637 ◽

Cited By ~ 115

Author(s):

Lars Prade ◽

Richard A Engh ◽

Andreas Girod ◽

Volker Kinzel ◽

Robert Huber ◽

...

Keyword(s):

Protein Kinase ◽

Conformational Changes ◽

Catalytic Subunit ◽

Dependent Protein Kinase ◽

Camp Dependent Protein Kinase ◽

Dependent Protein ◽

Inhibitory Potential

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cAMP exerts proliferative and anti-proliferative effects in pituitary cells of different types by activating both cAMP-dependent protein kinase A and exchange proteins directly activated by cAMP

Endocrine Abstracts ◽

10.1530/endoabs.32.p827 ◽

2013 ◽

Author(s):

Eleonora Vitali ◽

Erika Peverelli ◽

Giovanna Mantovani ◽

Elena Giardino ◽

Andrea G. Lania ◽

...

Keyword(s):

Protein Kinase ◽

Protein Kinase A ◽

Pituitary Cells ◽

Dependent Protein Kinase ◽

Camp Dependent Protein Kinase ◽

Different Types ◽

Dependent Protein ◽

Kinase A

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Faculty Opinions recommendation of Distal recognition sites in substrates are required for efficient phosphorylation by the cAMP-dependent protein kinase.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1165205.628140 ◽

2009 ◽

Author(s):

Jonathan Chernoff

Keyword(s):

Protein Kinase ◽

Dependent Protein Kinase ◽

Camp Dependent Protein Kinase ◽

Recognition Sites ◽

Dependent Protein

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Faculty Opinions recommendation of Differential regulation of CaV1.2 channels by cAMP-dependent protein kinase bound to A-kinase anchoring proteins 15 and 79/150.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.718291698.793492090 ◽

2014 ◽

Author(s):

Johannes Hell

Keyword(s):

Protein Kinase ◽

Differential Regulation ◽

Dependent Protein Kinase ◽

Camp Dependent Protein Kinase ◽

Anchoring Proteins ◽

Dependent Protein ◽

Cav1.2 Channels

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Rapid and reversible translocation of the catalytic subunit of cAMP-dependent protein kinase type II from the Golgi complex to the nucleus.

The EMBO Journal ◽

10.1002/j.1460-2075.1985.tb04006.x ◽

1985 ◽

Vol 4 (11) ◽

pp. 2801-2806 ◽

Cited By ~ 217

Author(s):

E.A. Nigg ◽

H. Hilz ◽

H.M. Eppenberger ◽

F. Dutly

Keyword(s):

Protein Kinase ◽

Golgi Complex ◽

Catalytic Subunit ◽

Type Ii ◽

Dependent Protein Kinase ◽

Camp Dependent Protein Kinase ◽

Dependent Protein

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