A Conserved Motif in the Tail Domain of Vinculin Mediates Association with and Insertion into Acidic Phospholipid Bilayers†

Biochemistry ◽  
1998 ◽  
Vol 37 (28) ◽  
pp. 10211-10222 ◽  
Author(s):  
Robert P. Johnson ◽  
Verena Niggli ◽  
Peter Durrer ◽  
Susan W. Craig
Keyword(s):  
Phospholipid Bilayers ◽  
Tail Domain ◽  
Conserved Motif ◽  
Acidic Phospholipid

scholarly journals Selective destabilization of acidic phospholipid bilayers performed by the hepatitis B virus fusion peptide

2000 ◽  
Vol 1463 (2) ◽  
pp. 419-428 ◽  
Author(s):  
Ignacio Rodrı́guez-Crespo ◽  
Belén Yélamos ◽  
Juan P. Albar ◽  
Darrell L. Peterson ◽  
Francisco Gavilanes
Keyword(s):  
Hepatitis B Virus ◽  
Hepatitis B ◽  
Fusion Peptide ◽  
Phospholipid Bilayers ◽  
Acidic Phospholipid ◽  
Virus Fusion ◽  
B Virus

First Nano-Infrared Spectroscopy and Imaging Measurements of Single Phospholipid Bilayers

2018 ◽  
Author(s):  
Adrian Cernescu ◽  
Michał Szuwarzyński ◽  
Urszula Kwolek ◽  
Karol Wolski ◽  
Paweł Wydro ◽  
...  
Keyword(s):  
Infrared Spectroscopy ◽  
Ir Spectroscopy ◽  
Absorption Band ◽  
Spectral Region ◽  
Near Field ◽  
Phospholipid Bilayers ◽  
Model Systems ◽  
Absorption Bands ◽  
Protein Complement ◽  
20 Nm

<div><div>Scattering-mode Scanning Near-Field Optical Microscopy (sSNOM) allows one to obtain absorption spectra in the mid-IR region for samples as small as 20 nm in size. This configuration has made it possible to measure FTIR spectra of the protein complement of membranes. (Amenabar 2013) We now show that mid-IR sSNOM has the sensitivity required to measure spectra of phospholipids in individual bilayers in the spectral range 800 cm<sup>-1</sup>–1400 cm<sup>-1</sup>. We have observed the main absorption bands of the dipalmitoylphosphatidylcholine headgroups in this spectral region above noise level. We have also mapped the phosphate absorption band at 1070 cm<sup>-1</sup> simultaneously with the AFM topography. We have shown that we could achieve sufficient contrast to discriminate between single and multiple phospholipid bilayers and other structures, such as liposomes. This work opens the way to further research that uses nano-IR spectroscopy to describe the biochemistry of cell membranes and model systems.</div></div><div></div>

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