Analysis of Nucleotide Insertion and Extension at 8-Oxo-7,8-dihydroguanine by Replicative T7 Polymerase exo-and Human Immunodeficiency Virus-1 Reverse Transcriptase Using Steady-State and Pre-Steady-State Kinetics†

Laura Lowe Furge; F. Peter Guengerich

doi:10.1021/bi9627267

Analysis of Nucleotide Insertion and Extension at 8-Oxo-7,8-dihydroguanine by Replicative T7 Polymerase exo-and Human Immunodeficiency Virus-1 Reverse Transcriptase Using Steady-State and Pre-Steady-State Kinetics†

Biochemistry ◽

10.1021/bi9627267 ◽

1997 ◽

Vol 36 (21) ◽

pp. 6475-6487 ◽

Cited By ~ 77

Author(s):

Laura Lowe Furge ◽

F. Peter Guengerich

Keyword(s):

Human Immunodeficiency Virus ◽

Steady State ◽

Reverse Transcriptase ◽

Steady State Kinetics ◽

Immunodeficiency Virus ◽

Nucleotide Insertion ◽

Human Immunodeficiency Virus 1 ◽

T7 Polymerase

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Misincorporation of dNTPs Opposite 1,N2-Ethenoguanine and 5,6,7,9-Tetrahydro-7-hydroxy-9-oxoimidazo[1,2-a]purine in Oligonucleotides byEscherichia coliPolymerases I exo-and II exo-, T7 Polymerase exo-, Human Immunodeficiency Virus-1 Reverse Transcriptase, and Rat Polymerase β†

Biochemistry ◽

10.1021/bi962526v ◽

1997 ◽

Vol 36 (20) ◽

pp. 6069-6079 ◽

Cited By ~ 39

Author(s):

Sophie Langouët ◽

Michael Müller ◽

F. Peter Guengerich

Keyword(s):

Human Immunodeficiency Virus ◽

Reverse Transcriptase ◽

Immunodeficiency Virus ◽

Human Immunodeficiency Virus 1 ◽

T7 Polymerase

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Human immunodeficiency virus reverse transcriptase: steady-state and pre-steady-state kinetics of nucleotide incorporation

Biochemistry ◽

10.1021/bi00133a013 ◽

1992 ◽

Vol 31 (18) ◽

pp. 4473-4479 ◽

Cited By ~ 109

Author(s):

John E. Reardon

Keyword(s):

Human Immunodeficiency Virus ◽

Steady State ◽

Reverse Transcriptase ◽

Steady State Kinetics ◽

Nucleotide Incorporation ◽

Immunodeficiency Virus ◽

Kinetics Of

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Studies on the mechanism of human immunodeficiency virus reverse transcriptase. Steady-state kinetics, processivity, and polynucleotide inhibition.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(19)37638-0 ◽

1988 ◽

Vol 263 (30) ◽

pp. 15657-15665 ◽

Cited By ~ 6

Author(s):

C Majumdar ◽

J Abbotts ◽

S Broder ◽

S H Wilson

Keyword(s):

Human Immunodeficiency Virus ◽

Steady State ◽

Reverse Transcriptase ◽

Steady State Kinetics ◽

Immunodeficiency Virus

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Psychotrine and its O-methyl ether are selective inhibitors of human immunodeficiency virus-1 reverse transcriptase.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(18)54314-3 ◽

1991 ◽

Vol 266 (35) ◽

pp. 23529-23536

Author(s):

G.T. Tan ◽

A.D. Kinghorn ◽

S.H. Hughes ◽

J.M. Pezzuto

Keyword(s):

Human Immunodeficiency Virus ◽

Reverse Transcriptase ◽

Methyl Ether ◽

Selective Inhibitors ◽

Immunodeficiency Virus ◽

Human Immunodeficiency Virus 1

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Human immunodeficiency virus 1 (HIV-1) reverse transcriptase (RT)

Emerging Therapeutic Targets ◽

10.1517/14728222.2.2.239 ◽

1998 ◽

Vol 2 (2) ◽

pp. 239-243

Author(s):

Elias Argyris ◽

Yvonne Paterson

Keyword(s):

Human Immunodeficiency Virus ◽

Reverse Transcriptase ◽

Immunodeficiency Virus ◽

Hiv 1 ◽

Human Immunodeficiency Virus 1

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The Proteinase Inhibitor Pepstatin A Inhibits Formation of Reverse Transcriptase in H9 Cells Infected with Human Immunodeficiency Virus 1

AIDS Research and Human Retroviruses ◽

10.1089/aid.1989.5.269 ◽

1989 ◽

Vol 5 (3) ◽

pp. 269-274 ◽

Cited By ~ 12

Author(s):

BJØRN GRINDE ◽

OLAV HUNGNES ◽

ENOK TJØTTA

Keyword(s):

Human Immunodeficiency Virus ◽

Reverse Transcriptase ◽

Proteinase Inhibitor ◽

Immunodeficiency Virus ◽

Pepstatin A ◽

Human Immunodeficiency Virus 1

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Expression of Polypeptides of Human Immunodeficiency Virus-1 Reverse Transcriptase in Escherichia coli

Protein Expression and Purification ◽

10.1006/prep.1993.1025 ◽

1993 ◽

Vol 4 (3) ◽

pp. 187-199 ◽

Cited By ~ 8

Author(s):

S.P. Becerra ◽

A. Kumar ◽

S.H. Wilson

Keyword(s):

Escherichia Coli ◽

Human Immunodeficiency Virus ◽

Reverse Transcriptase ◽

Immunodeficiency Virus ◽

Human Immunodeficiency Virus 1

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Stabilization and activation of recombinant human immunodeficiency virus-1 reverse transcriptase-P66

Biochemical and Biophysical Research Communications ◽

10.1016/0006-291x(90)92078-e ◽

1990 ◽

Vol 167 (2) ◽

pp. 673-679 ◽

Cited By ~ 14

Author(s):

Gerald L. Rowley ◽

Qi-Feng Ma ◽

Ian C. Bathurst ◽

Philip J. Barr ◽

George L. Kenyon

Keyword(s):

Human Immunodeficiency Virus ◽

Reverse Transcriptase ◽

Immunodeficiency Virus ◽

Human Immunodeficiency Virus 1

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The Y271 and I274 Amino Acids in Reverse Transcriptase of Human Immunodeficiency Virus-1 Are Critical to Protein Stability

PLoS ONE ◽

10.1371/journal.pone.0006108 ◽

2009 ◽

Vol 4 (7) ◽

pp. e6108 ◽

Cited By ~ 5

Author(s):

Hao-Jie Zhang ◽

Yong-Xiang Wang ◽

Hao Wu ◽

Dong-Yan Jin ◽

Yu-Mei Wen ◽

...

Keyword(s):

Amino Acids ◽

Human Immunodeficiency Virus ◽

Reverse Transcriptase ◽

Protein Stability ◽

Immunodeficiency Virus ◽

Human Immunodeficiency Virus 1

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An open randomised trial to evaluate the activity and tolerability of combinations of reverse transcriptase and protease inhibitors, including induction therapy, in individuals with Human Immunodeficiency Virus-1 (HIV-1) infection and CD4 cell counts greater than 25 x 10 to the power of 6 per litre

http://isrctn.org/> ◽

10.1186/isrctn58987964 ◽

2012 ◽

Author(s):

Malcolm Hooker

Keyword(s):

Human Immunodeficiency Virus ◽

Reverse Transcriptase ◽

Protease Inhibitors ◽

Randomised Trial ◽

Cell Counts ◽

Cd4 Cell Counts ◽

Immunodeficiency Virus ◽

Cd4 Cell ◽

Hiv 1 ◽

Human Immunodeficiency Virus 1

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