Flip-Flop Is the Rate-Limiting Step for Transport of Free Fatty Acids across Lipid Vesicle Membranes

Biochemistry ◽  
2009 ◽  
Vol 48 (43) ◽  
pp. 10437-10445 ◽  
Author(s):  
Andrew N. Carley ◽  
Alan M. Kleinfeld
Keyword(s):  
Fatty Acids ◽  
Free Fatty Acids ◽  
Lipid Vesicle ◽  
Flip Flop ◽  
Rate Limiting Step ◽  
Vesicle Membranes ◽  
Limiting Step ◽  
Rate Limiting

Anaerobic batch degradation of solid poultry slaughterhouse waste

2000 ◽  
Vol 41 (3) ◽  
pp. 33-41 ◽  
Author(s):  
E. Salminen ◽  
J. Rintala ◽  
L.Ya. Lokshina ◽  
V.A. Vavilin
Keyword(s):  
Fatty Acids ◽  
Methane Production ◽  
Long Chain Fatty Acids ◽  
Rate Limiting Step ◽  
Limiting Step ◽  
Propionate Degradation ◽  
Waste Degradation ◽  
New Generation ◽  
Rate Limiting ◽  
Long Chain

We studied anaerobic batch degradation of solid poultry slaughterhouse wastes with different initial waste and inoculum concentrations and waste-to-inoculum ratios and simulated the dynamics of the process with a new generation <METHANE> model. Our modelling results suggest that inhibited propionate degradation by long-chain fatty acids (LCFA) and inhibited hydrolysis by a high propionate concentration constituted the rate-limiting step in the waste degradation. Palmitate was the most abundant LCFA in the assays. Within 27 days of incubation, up to 0.55 to 0.67 m3 of methane (STP)/kg VS added was produced under the studied conditions. Lower waste-to-inoculum ratios exhibited a faster onset and rate of specific methane production. In all the assays, ammonification occurred within 3 to 6 days and accounted for 50 to 60% of total nitrogen.

Ornithine Decarboxylase Activity in Cultured Endothelial Cells Stimulated by Serum, Thrombin and Serotonin

1978 ◽  
Vol 39 (02) ◽  
pp. 496-503 ◽  
Author(s):  
P A D’Amore ◽  
H B Hechtman ◽  
D Shepro
Keyword(s):  
Endothelial Cells ◽  
Ornithine Decarboxylase ◽  
Decarboxylase Activity ◽  
Aortic Endothelial Cells ◽  
Ornithine Decarboxylase Activity ◽  
Rate Limiting Step ◽  
Bovine Aortic Endothelial Cells ◽  
Limiting Step ◽  
Rate Limiting ◽  
Serum Serotonin

SummaryOrnithine decarboxylase (ODC) activity, the rate-limiting step in the synthesis of polyamines, can be demonstrated in cultured, bovine, aortic endothelial cells (EC). Serum, serotonin and thrombin produce a rise in ODC activity. The serotonin-induced ODC activity is significantly blocked by imipramine (10-5 M) or Lilly 11 0140 (10-6M). Preincubation of EC with these blockers together almost completely depresses the 5-HT-stimulated ODC activity. These observations suggest a manner by which platelets may maintain EC structural and metabolic soundness.

Dynamics of hepatic and peripheral insulin effects suggest common rate-limiting step in vivo

Diabetes ◽  
1993 ◽  
Vol 42 (2) ◽  
pp. 296-306 ◽  
Author(s):  
D. C. Bradley ◽  
R. A. Poulin ◽  
R. N. Bergman
Keyword(s):  
Rate Limiting Step ◽  
Limiting Step ◽  
Rate Limiting
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